52 items (Leptonychotes weddellii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PSMD8	LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 8. (351 aa)
	PSMD4	26S proteasome non-ATPase regulatory subunit 4. (377 aa)
	PSMB4	Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
	PSMB10	Proteasome subunit beta. (273 aa)
	CUL1	Cullin-1; Belongs to the cullin family. (327 aa)
	SKP1	S-phase kinase-associated protein 1 isoform X1; Belongs to the SKP1 family. (163 aa)
	LOC102728200	ubiquitin-40S ribosomal protein S27a-like. (154 aa)
	PSMC2	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
	PSMA6	Proteasome subunit alpha type. (246 aa)
	LOC102742178	Proteasome subunit alpha type. (234 aa)
	LOC102750322	polyubiquitin-B-like. (153 aa)
	PSMB2	Proteasome subunit beta. (201 aa)
	LOC102734657	26S proteasome non-ATPase regulatory subunit 1-like. (279 aa)
	LOC102729636	polyubiquitin-B-like. (77 aa)
	PSMC6	26S protease regulatory subunit 10B. (291 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14. (955 aa)
	PSMD14	26S proteasome non-ATPase regulatory subunit 14. (310 aa)
	UBA3	NEDD8-activating enzyme E1 catalytic subunit isoform X1. (463 aa)
	PSMC5	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
	PSMB8	Proteasome subunit beta. (276 aa)
	LOC102733981	26S proteasome non-ATPase regulatory subunit 2-like. (125 aa)
	PSME1	Proteasome activator complex subunit 1 isoform X1. (249 aa)
	PSME2	Proteasome activator complex subunit 2 isoform X1. (239 aa)
	PSME3	Proteasome activator complex subunit 3 isoform X3. (254 aa)
	CHUK	Inhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
	PSMD7	26S proteasome non-ATPase regulatory subunit 7-like. (324 aa)
	PSMB6	Proteasome subunit beta. (239 aa)
	PSMA3	Proteasome subunit alpha type. (255 aa)
	PSMD11	26S proteasome non-ATPase regulatory subunit 11. (422 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	LOC102749983	F-box/WD repeat-containing protein 11-like. (264 aa)
	PSMA8	Proteasome subunit alpha type. (250 aa)
	PSMF1	Proteasome inhibitor PI31 subunit. (128 aa)
	PSMB5	Proteasome subunit beta type-5. (160 aa)
	PSMB11	Proteasome subunit beta. (285 aa)
	PSMD9	26S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
	KXD1	kxDL motif-containing protein 1 isoform X1. (176 aa)
	UBA52	ubiquitin-60S ribosomal protein L40 isoform X3. (128 aa)
	UBE2M	NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
	LOC102747337	ubiquitin-40S ribosomal protein S27a-like. (154 aa)
	LOC102735127	26S protease regulatory subunit 4-like isoform X1; Belongs to the AAA ATPase family. (440 aa)
	PSMA4	Proteasome subunit alpha type. (261 aa)
	LOC102737749	Transcription factor RelB-like. (167 aa)
	PSMD10	26S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
	PSMA5	Proteasome subunit alpha type. (235 aa)
	LOC102726381	26S proteasome non-ATPase regulatory subunit 1-like. (574 aa)
	PSMD6	26S proteasome non-ATPase regulatory subunit 6 isoform X1. (389 aa)
	NFKB2	Nuclear factor NF-kappa-B p100 subunit. (900 aa)
	LOC102729219	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (778 aa)
	LOC102732367	Proteasome subunit beta type-1-like. (140 aa)
	LOC102735156	Proteasome subunit beta type-5-like. (119 aa)
	LOC102746862	ubiquitin-40S ribosomal protein S27a-like isoform X1. (156 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHUK	CUL1	A0A2U3YBY3	A0A2U3XHJ1	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	Cullin-1; Belongs to the cullin family.	0.566
CHUK	LOC102728200	A0A2U3YBY3	A0A2U3XJ47	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	ubiquitin-40S ribosomal protein S27a-like.	0.535
CHUK	LOC102729636	A0A2U3YBY3	A0A2U3XSD5	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	polyubiquitin-B-like.	0.509
CHUK	LOC102737749	A0A2U3YBY3	A0A2U3YXH0	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	Transcription factor RelB-like.	0.979
CHUK	LOC102746862	A0A2U3YBY3	A0A2U3Z815	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	ubiquitin-40S ribosomal protein S27a-like isoform X1.	0.535
CHUK	LOC102747337	A0A2U3YBY3	A0A2U3YWH0	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	ubiquitin-40S ribosomal protein S27a-like.	0.535
CHUK	LOC102749983	A0A2U3YBY3	A0A2U3YNR1	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	F-box/WD repeat-containing protein 11-like.	0.621
CHUK	LOC102750322	A0A2U3YBY3	A0A2U3XMJ2	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	polyubiquitin-B-like.	0.596
CHUK	MAP3K14	A0A2U3YBY3	A0A2U3XWU0	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	Mitogen-activated protein kinase kinase kinase 14.	0.984
CHUK	NFKB2	A0A2U3YBY3	A0A2U3Z5U0	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	Nuclear factor NF-kappa-B p100 subunit.	0.942
CHUK	SKP1	A0A2U3YBY3	A0A2U3XI17	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	S-phase kinase-associated protein 1 isoform X1; Belongs to the SKP1 family.	0.562
CHUK	UBA52	A0A2U3YBY3	A0A2U3YV30	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	ubiquitin-60S ribosomal protein L40 isoform X3.	0.631
CUL1	CHUK	A0A2U3XHJ1	A0A2U3YBY3	Cullin-1; Belongs to the cullin family.	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	0.566
CUL1	LOC102726381	A0A2U3XHJ1	A0A2U3Z331	Cullin-1; Belongs to the cullin family.	26S proteasome non-ATPase regulatory subunit 1-like.	0.612
CUL1	LOC102728200	A0A2U3XHJ1	A0A2U3XJ47	Cullin-1; Belongs to the cullin family.	ubiquitin-40S ribosomal protein S27a-like.	0.771
CUL1	LOC102729219	A0A2U3XHJ1	A0A2U3Z6Q4	Cullin-1; Belongs to the cullin family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.544
CUL1	LOC102729636	A0A2U3XHJ1	A0A2U3XSD5	Cullin-1; Belongs to the cullin family.	polyubiquitin-B-like.	0.778
CUL1	LOC102732367	A0A2U3XHJ1	A0A2U3Z731	Cullin-1; Belongs to the cullin family.	Proteasome subunit beta type-1-like.	0.568
CUL1	LOC102733981	A0A2U3XHJ1	A0A2U3Y3C6	Cullin-1; Belongs to the cullin family.	26S proteasome non-ATPase regulatory subunit 2-like.	0.544
CUL1	LOC102734657	A0A2U3XHJ1	A0A2U3XS75	Cullin-1; Belongs to the cullin family.	26S proteasome non-ATPase regulatory subunit 1-like.	0.612