40 items (Leptonychotes weddellii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATP7A	Copper-transporting ATPase 1 isoform X1. (1498 aa)
	DEFB119	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (83 aa)
	DEFB127	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (100 aa)
	BPIFA1	BPI fold-containing family A member 1. (255 aa)
	DEFB128	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (94 aa)
	DEFB121	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (61 aa)
	DEFB132	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (109 aa)
	DEFB129	LOW QUALITY PROTEIN: beta-defensin 129. (189 aa)
	DEFB125	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (116 aa)
	LOC102731937	PDZ domain-containing protein 11-like. (142 aa)
	RNASE7	Ribonuclease 7; Belongs to the pancreatic ribonuclease family. (171 aa)
	TLR1	Toll-like receptor 1; Belongs to the Toll-like receptor family. (794 aa)
	CAMP	Cathelicidin antimicrobial peptide. (171 aa)
	LOC102734272	Uncharacterized protein C18orf8 homolog isoform X1. (596 aa)
	LEAP2	Liver-expressed antimicrobial peptide 2. (77 aa)
	ANKRD16	Ankyrin repeat domain-containing protein 16. (364 aa)
	LOC102727613	Beta-defensin 130-like. (79 aa)
	LOC102729137	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (79 aa)
	LOC102728832	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (66 aa)
	PGLYRP2	N-acetylmuramoyl-L-alanine amidase. (605 aa)
	LOC102726710	Beta-defensin 103A-like. (67 aa)
	ATOX1	Copper transport protein ATOX1. (68 aa)
	CTSG	Cathepsin G; Belongs to the peptidase S1 family. (251 aa)
	ELANE	LOW QUALITY PROTEIN: neutrophil elastase; Belongs to the peptidase S1 family. (284 aa)
	DEFB1	Beta-defensin 1 isoform X1. (69 aa)
	LOC102739415	Cationic trypsin-like; Belongs to the peptidase S1 family. (246 aa)
	LOC102738811	Anionic trypsin-like; Belongs to the peptidase S1 family. (248 aa)
	PGLYRP1	Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa)
	BPIFB3	BPI fold-containing family B member 3. (472 aa)
	BPIFB2	BPI fold-containing family B member 2. (280 aa)
	PGLYRP4	Peptidoglycan recognition protein 4. (371 aa)
	LOC102749524	LOW QUALITY PROTEIN: duodenase-1-like; Belongs to the peptidase S1 family. (251 aa)
	GZMB	Granzyme B; Belongs to the peptidase S1 family. (259 aa)
	LOC102725662	PDZ domain-containing protein 11-like isoform X2. (140 aa)
	SLC11A1	Natural resistance-associated macrophage protein 1 isoform X1. (547 aa)
	CCR6	c-C chemokine receptor type 6; Belongs to the G-protein coupled receptor 1 family. (375 aa)
	LOC102741358	Protein S100; Belongs to the S-100 family. (89 aa)
	LOC102727192	BPI fold-containing family B member 4-like. (471 aa)
	DEFB118	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. (107 aa)
	LYZ	Lysozyme C; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. (148 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATOX1	ATP7A	A0A2U3XZX1	A0A2U3X667	Copper transport protein ATOX1.	Copper-transporting ATPase 1 isoform X1.	0.997
ATP7A	ATOX1	A0A2U3X667	A0A2U3XZX1	Copper-transporting ATPase 1 isoform X1.	Copper transport protein ATOX1.	0.997
ATP7A	LOC102725662	A0A2U3X667	A0A2U3YY08	Copper-transporting ATPase 1 isoform X1.	PDZ domain-containing protein 11-like isoform X2.	0.944
ATP7A	LOC102731937	A0A2U3X667	A0A2U3XF16	Copper-transporting ATPase 1 isoform X1.	PDZ domain-containing protein 11-like.	0.928
BPIFA1	BPIFB2	A0A2U3X7X6	A0A2U3YSJ7	BPI fold-containing family A member 1.	BPI fold-containing family B member 2.	0.647
BPIFA1	BPIFB3	A0A2U3X7X6	A0A2U3YSH7	BPI fold-containing family A member 1.	BPI fold-containing family B member 3.	0.476
BPIFA1	LOC102727192	A0A2U3X7X6	A0A2U3Z7I6	BPI fold-containing family A member 1.	BPI fold-containing family B member 4-like.	0.761
BPIFB2	BPIFA1	A0A2U3YSJ7	A0A2U3X7X6	BPI fold-containing family B member 2.	BPI fold-containing family A member 1.	0.647
BPIFB2	BPIFB3	A0A2U3YSJ7	A0A2U3YSH7	BPI fold-containing family B member 2.	BPI fold-containing family B member 3.	0.488
BPIFB2	LOC102727192	A0A2U3YSJ7	A0A2U3Z7I6	BPI fold-containing family B member 2.	BPI fold-containing family B member 4-like.	0.518
BPIFB3	BPIFA1	A0A2U3YSH7	A0A2U3X7X6	BPI fold-containing family B member 3.	BPI fold-containing family A member 1.	0.476
BPIFB3	BPIFB2	A0A2U3YSH7	A0A2U3YSJ7	BPI fold-containing family B member 3.	BPI fold-containing family B member 2.	0.488
CAMP	DEFB1	A0A2U3XNL1	A0A2U3YBZ6	Cathelicidin antimicrobial peptide.	Beta-defensin 1 isoform X1.	0.526
CAMP	DEFB125	A0A2U3XNL1	A0A2U3X882	Cathelicidin antimicrobial peptide.	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.	0.471
CAMP	ELANE	A0A2U3XNL1	A0A2U3YB47	Cathelicidin antimicrobial peptide.	LOW QUALITY PROTEIN: neutrophil elastase; Belongs to the peptidase S1 family.	0.755
CAMP	LOC102741358	A0A2U3XNL1	A0A2U3Z6I1	Cathelicidin antimicrobial peptide.	Protein S100; Belongs to the S-100 family.	0.628
CAMP	PGLYRP1	A0A2U3XNL1	A0A2U3YMS9	Cathelicidin antimicrobial peptide.	Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity.	0.747
CTSG	ELANE	A0A2U3Y7G0	A0A2U3YB47	Cathepsin G; Belongs to the peptidase S1 family.	LOW QUALITY PROTEIN: neutrophil elastase; Belongs to the peptidase S1 family.	0.755
CTSG	LOC102738811	A0A2U3Y7G0	A0A2U3YIS5	Cathepsin G; Belongs to the peptidase S1 family.	Anionic trypsin-like; Belongs to the peptidase S1 family.	0.471
CTSG	LOC102739415	A0A2U3Y7G0	A0A2U3YIR8	Cathepsin G; Belongs to the peptidase S1 family.	Cationic trypsin-like; Belongs to the peptidase S1 family.	0.466