STRINGSTRING
LOC102748019 LOC102748019 LOC102739655 LOC102739655 LOC102750992 LOC102750992 LOC102725568 LOC102725568 LOC102730207 LOC102730207 PSMD10 PSMD10 RFC5 RFC5 CDC16 CDC16 PSMA5 PSMA5 LOC102730819 LOC102730819 LOC102745317 LOC102745317 LOC102745013 LOC102745013 LOC102726381 LOC102726381 LOC102750135 LOC102750135 ORC6 ORC6 PSMD6 PSMD6 LOC102743898 LOC102743898 ANAPC7 ANAPC7 LOC102729219 LOC102729219 LOC102732367 LOC102732367 LOC102735156 LOC102735156 LOC102746675 LOC102746675 LOC102746862 LOC102746862 LOC102730851 LOC102730851 RPA4 RPA4 LOC102746125 LOC102746125 CDK3 CDK3 PSMD4 PSMD4 PSMB4 PSMB4 CDK2 CDK2 CDC7 CDC7 DNA2 DNA2 RFC3 RFC3 POLE2 POLE2 DBF4 DBF4 CCNE2 CCNE2 RBX1 RBX1 PSMB10 PSMB10 POLA1 POLA1 CUL1 CUL1 SKP1 SKP1 ANAPC16 ANAPC16 LOC102728200 LOC102728200 PSMC2 PSMC2 PSMA6 PSMA6 LOC102731039 LOC102731039 LOC102742178 LOC102742178 LOC102750322 LOC102750322 PSMB2 PSMB2 GINS3 GINS3 MCM4 MCM4 LOC102734657 LOC102734657 LOC102729636 LOC102729636 KPNA5 KPNA5 LOC102740480 LOC102740480 CDC26 CDC26 POLE3 POLE3 UBE2C UBE2C MCM8 MCM8 PCNA PCNA PSMC6 PSMC6 LOC102742187 LOC102742187 LOC102744317 LOC102744317 LOC102739804 LOC102739804 LOC102726286 LOC102726286 PSMD14 PSMD14 LOC102746084 LOC102746084 LOC102750817 LOC102750817 LOC102728431 LOC102728431 POLE4 POLE4 POLD2 POLD2 LOC102732990 LOC102732990 RPA3 RPA3 LOC102737083 LOC102737083 LOC102738290 LOC102738290 ANAPC5 ANAPC5 RCBTB1 RCBTB1 ANAPC4 ANAPC4 CDC23 CDC23 POLA2 POLA2 FAM89B FAM89B ANAPC2 ANAPC2 PSMC5 PSMC5 LOC102738587 LOC102738587 TM7SF3 TM7SF3 PSMB8 PSMB8 LOC102733981 LOC102733981 ORC5 ORC5 PSME1 PSME1 PSME2 PSME2 PSME3 PSME3 FZR1 FZR1 LOC102726804 LOC102726804 CCNE1 CCNE1 GMNN GMNN PSMD8 PSMD8 MCM9 MCM9 MEIOB MEIOB PSMD7 PSMD7 ANAPC11 ANAPC11 PSMB6 PSMB6 LOC102746412 LOC102746412 RFC4 RFC4 KPNA1 KPNA1 POLD4 POLD4 ANAPC10 ANAPC10 PSMA3 PSMA3 PSMD11 PSMD11 PSMA7 PSMA7 KPNB1 KPNB1 PSMA8 PSMA8 MCM5 MCM5 ANAPC15 ANAPC15 POLE POLE PSMF1 PSMF1 RFC2 RFC2 CDC6 CDC6 PSMB5 PSMB5 PSMB11 PSMB11 PSMD9 PSMD9 GINS4 GINS4 LOC102732330 LOC102732330 KXD1 KXD1 FAM89A FAM89A UBA52 UBA52 LOC102747337 LOC102747337 LOC102735127 LOC102735127 MCM7 MCM7 PSMA4 PSMA4 UBE2S UBE2S LOC102730711 LOC102730711
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102748019DNA replication licensing factor MCM3-like; Belongs to the MCM family. (605 aa)
LOC102739655DNA replication licensing factor MCM3-like. (177 aa)
LOC102750992Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC102725568Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC102730207Histone H2A; Belongs to the histone H2A family. (143 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
RFC5Replication factor C subunit 5 isoform X1. (340 aa)
CDC16Cell division cycle protein 16 homolog isoform X1. (620 aa)
PSMA5Proteasome subunit alpha type. (235 aa)
LOC102730819Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102745317Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102745013Histone H3; Belongs to the histone H3 family. (136 aa)
LOC10272638126S proteasome non-ATPase regulatory subunit 1-like. (574 aa)
LOC102750135DNA helicase MCM9-like. (234 aa)
ORC6Origin recognition complex subunit 6. (252 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (389 aa)
LOC102743898Histone H2B type W-T-like; Belongs to the histone H2B family. (174 aa)
ANAPC7Anaphase-promoting complex subunit 7. (461 aa)
LOC10272921926S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (778 aa)
LOC102732367Proteasome subunit beta type-1-like. (140 aa)
LOC102735156Proteasome subunit beta type-5-like. (119 aa)
LOC102746675DNA primase small subunit-like. (156 aa)
LOC102746862ubiquitin-40S ribosomal protein S27a-like isoform X1. (156 aa)
LOC10273085126S protease regulatory subunit 6A-like. (200 aa)
RPA4LOW QUALITY PROTEIN: replication protein A4, 30kDa. (262 aa)
LOC102746125LOW QUALITY PROTEIN: cyclin-A1-like; Belongs to the cyclin family. (463 aa)
CDK3Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4. (377 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
CDC7Cell division cycle 7-related protein kinase isoform X1. (575 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2. (1061 aa)
RFC3Replication factor C subunit 3. (356 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
DBF4Protein DBF4 homolog A isoform X1. (676 aa)
CCNE2G1/S-specific cyclin-E2; Belongs to the cyclin family. (344 aa)
RBX1E3 ubiquitin-protein ligase RBX1 isoform X3. (108 aa)
PSMB10Proteasome subunit beta. (273 aa)
POLA1DNA polymerase. (1423 aa)
CUL1Cullin-1; Belongs to the cullin family. (327 aa)
SKP1S-phase kinase-associated protein 1 isoform X1; Belongs to the SKP1 family. (163 aa)
ANAPC16Anaphase-promoting complex subunit 16 isoform X1. (110 aa)
LOC102728200ubiquitin-40S ribosomal protein S27a-like. (154 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
LOC102731039Histone H3.3-like. (128 aa)
LOC102742178Proteasome subunit alpha type. (234 aa)
LOC102750322polyubiquitin-B-like. (153 aa)
PSMB2Proteasome subunit beta. (201 aa)
GINS3DNA replication complex GINS protein PSF3 isoform X1. (216 aa)
MCM4DNA helicase; Belongs to the MCM family. (863 aa)
LOC10273465726S proteasome non-ATPase regulatory subunit 1-like. (279 aa)
LOC102729636polyubiquitin-B-like. (77 aa)
KPNA5Importin subunit alpha; Functions in nuclear protein import. (539 aa)
LOC102740480DNA replication complex GINS protein PSF2-like. (114 aa)
CDC26Anaphase-promoting complex subunit CDC26. (85 aa)
POLE3DNA polymerase epsilon subunit 3. (147 aa)
UBE2CUbiquitin-conjugating enzyme E2 C isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
MCM8DNA helicase MCM8 isoform X1; Belongs to the MCM family. (833 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
PSMC626S protease regulatory subunit 10B. (291 aa)
LOC102742187Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102744317Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102739804Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102726286Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (78 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
LOC102746084Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC102750817Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102728431Histone H2B; Belongs to the histone H2B family. (119 aa)
POLE4DNA polymerase epsilon subunit 4. (116 aa)
POLD2DNA polymerase delta subunit 2. (469 aa)
LOC102732990Histone H2A; Belongs to the histone H2A family. (140 aa)
RPA3Replication protein A 14 kDa subunit. (121 aa)
LOC102737083Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102738290Histone H2B; Belongs to the histone H2B family. (126 aa)
ANAPC5Anaphase-promoting complex subunit 5 isoform X1. (755 aa)
RCBTB1RCC1 and BTB domain-containing protein 1. (531 aa)
ANAPC4Anaphase-promoting complex subunit 4-like. (280 aa)
CDC23Cell division cycle protein 23 homolog. (597 aa)
POLA2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (595 aa)
FAM89BProtein FAM89B isoform X1. (192 aa)
ANAPC2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (818 aa)
PSMC526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
LOC102738587Histone H2B subacrosomal variant-like; Belongs to the histone H2B family. (122 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
PSMB8Proteasome subunit beta. (276 aa)
LOC10273398126S proteasome non-ATPase regulatory subunit 2-like. (125 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
PSME1Proteasome activator complex subunit 1 isoform X1. (249 aa)
PSME2Proteasome activator complex subunit 2 isoform X1. (239 aa)
PSME3Proteasome activator complex subunit 3 isoform X3. (254 aa)
FZR1Fizzy-related protein homolog isoform X1. (496 aa)
LOC102726804Histone H2B; Belongs to the histone H2B family. (126 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa)
GMNNGeminin. (210 aa)
PSMD8LOW QUALITY PROTEIN: 26S proteasome non-ATPase regulatory subunit 8. (351 aa)
MCM9DNA helicase MCM9; Belongs to the MCM family. (898 aa)
MEIOBMeiosis-specific with OB domain-containing protein. (300 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7-like. (324 aa)
ANAPC11Anaphase-promoting complex subunit 11 isoform X1. (84 aa)
PSMB6Proteasome subunit beta. (239 aa)
LOC102746412Replication protein A 32 kDa subunit-like. (124 aa)
RFC4Replication factor C subunit 4. (363 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
POLD4DNA polymerase delta subunit 4. (107 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
KPNB1Importin subunit beta-1 isoform X3. (876 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
ANAPC15Anaphase-promoting complex subunit 15 isoform X1. (155 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2277 aa)
PSMF1Proteasome inhibitor PI31 subunit. (128 aa)
RFC2Replication factor C subunit 2 isoform X1. (368 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (559 aa)
PSMB5Proteasome subunit beta type-5. (160 aa)
PSMB11Proteasome subunit beta. (285 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
GINS4DNA replication complex GINS protein SLD5. (162 aa)
LOC102732330Histone H3; Belongs to the histone H3 family. (136 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (176 aa)
FAM89AProtein FAM89A. (170 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X3. (128 aa)
LOC102747337ubiquitin-40S ribosomal protein S27a-like. (154 aa)
LOC10273512726S protease regulatory subunit 4-like isoform X1; Belongs to the AAA ATPase family. (440 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (155 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
UBE2SUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (220 aa)
LOC102730711DNA replication licensing factor MCM2-like. (149 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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