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| | LOC102744185 | tyrosyl-DNA phosphodiesterase 1-like. (361 aa) |
| | PIAS1 | E3 SUMO-protein ligase PIAS1 isoform X1. (653 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (391 aa) |
| | ENKD1 | Enkurin domain-containing protein 1. (346 aa) |
| | LOC102730207 | Histone H2A; Belongs to the histone H2A family. (143 aa) |
| | LOC102725568 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | ALKBH7 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial. (221 aa) |
| | POLH | DNA polymerase eta isoform X1. (712 aa) |
| | LOC102750992 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | ABL1 | Tyrosine-protein kinase ABL1-like. (312 aa) |
| | CETN2 | Centrin-2. (187 aa) |
| | LOC102750113 | Importin subunit alpha; Functions in nuclear protein import. (523 aa) |
| | LOC102732536 | DNA repair protein complementing XP-C cells-like. (544 aa) |
| | POLR2C | DNA-directed RNA polymerase II subunit RPB3. (98 aa) |
| | ADPRHL2 | poly(ADP-ribose) glycohydrolase ARH3. (352 aa) |
| | TRIM65 | Tripartite motif-containing protein 65. (381 aa) |
| | LOC102748814 | Poly [ADP-ribose] polymerase 1-like. (337 aa) |
| | EYA3 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (434 aa) |
| | COPS6 | COP9 signalosome complex subunit 6. (321 aa) |
| | LOC102726250 | Ubiquitin fusion degradation protein 1 homolog. (117 aa) |
| | MSH3 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1126 aa) |
| | NRDE2 | Protein NRDE2 homolog. (1168 aa) |
| | LOC102747337 | ubiquitin-40S ribosomal protein S27a-like. (154 aa) |
| | TCEANC | Transcription elongation factor A N-terminal and central domain-containing protein. (368 aa) |
| | LOC102732340 | DNA-(Apurinic or apyrimidinic site) lyase 2-like. (90 aa) |
| | POLR2F | DNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa) |
| | EXO1 | LOW QUALITY PROTEIN: exonuclease 1. (793 aa) |
| | LOC102746732 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | PHF3 | PHD finger protein 3. (2040 aa) |
| | UBA52 | ubiquitin-60S ribosomal protein L40 isoform X3. (128 aa) |
| | KXD1 | kxDL motif-containing protein 1 isoform X1. (176 aa) |
| | LOC102746625 | Lysine-specific demethylase 4A-like. (404 aa) |
| | FAM175A | BRCA1-A complex subunit Abraxas. (192 aa) |
| | PMS2 | Mismatch repair endonuclease PMS2. (859 aa) |
| | ERCC3 | TFIIH basal transcription factor complex helicase XPB subunit. (782 aa) |
| | SUMO3 | Small ubiquitin-related modifier. (111 aa) |
| | APITD1 | Centromere protein S. (141 aa) |
| | LOC102745606 | Ubiquitin carboxyl-terminal hydrolase 43-like. (411 aa) |
| | GTF2H1 | General transcription factor IIH subunit 1. (441 aa) |
| | FANCA | Fanconi anemia group A protein. (1453 aa) |
| | LOC102731205 | Ubiquitin carboxyl-terminal hydrolase 43-like; Belongs to the peptidase C19 family. (535 aa) |
| | RFC2 | Replication factor C subunit 2 isoform X1. (368 aa) |
| | LOC102749897 | A-kinase anchor protein 7 isoforms alpha and beta-like. (104 aa) |
| | LOC102726037 | UV-stimulated scaffold protein A-like. (261 aa) |
| | PWWP2A | PWWP domain-containing protein 2A. (755 aa) |
| | ZNF830 | Zinc finger protein 830. (371 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2277 aa) |
| | XRCC2 | DNA repair protein XRCC2. (280 aa) |
| | INO80C | INO80 complex subunit C. (191 aa) |
| | COPS3 | COP9 signalosome complex subunit 3. (423 aa) |
| | NEIL1 | Endonuclease 8-like 1. (383 aa) |
| | EYA2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (251 aa) |
| | RMI1 | recQ-mediated genome instability protein 1. (638 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase. (686 aa) |
| | POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) |
| | DTL | Denticleless protein homolog isoform X1. (730 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa) |
| | BAZ1B | Tyrosine-protein kinase BAZ1B. (1443 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa) |
| | POLD4 | DNA polymerase delta subunit 4. (107 aa) |
| | BRE | BRCA1-A complex subunit BRE. (363 aa) |
| | PRPF19 | pre-mRNA-processing factor 19 isoform X1. (504 aa) |
| | RFC4 | Replication factor C subunit 4. (363 aa) |
| | DCLRE1A | DNA cross-link repair 1A protein. (953 aa) |
| | LOC102746412 | Replication protein A 32 kDa subunit-like. (124 aa) |
| | GPS1 | COP9 signalosome complex subunit 1. (527 aa) |
| | SIRT7 | NAD-dependent protein deacetylase sirtuin-7. (251 aa) |
| | XPA | DNA repair protein complementing XP-A cells. (273 aa) |
| | LOC102725723 | Solute carrier family 23 member 3-like. (227 aa) |
| | ANKRD32 | Ankyrin repeat domain-containing protein 32 isoform X1. (1057 aa) |
| | ISY1 | pre-mRNA-splicing factor ISY1 homolog. (285 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (267 aa) |
| | LOC102739117 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (187 aa) |
| | TCEA1 | Transcription elongation factor A protein 1 isoform X1. (301 aa) |
| | VWA5A | Von Willebrand factor A domain-containing protein 5A-like. (784 aa) |
| | COPS4 | COP9 signalosome complex subunit 4 isoform X1. (406 aa) |
| | EME2 | Probable crossover junction endonuclease EME2. (324 aa) |
| | LOC102740606 | SUMO-conjugating enzyme UBC9-like; Belongs to the ubiquitin-conjugating enzyme family. (123 aa) |
| | MEIOB | Meiosis-specific with OB domain-containing protein. (300 aa) |
| | NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (314 aa) |
| | RHNO1 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 isoform X1. (255 aa) |
| | POLR2L | DNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa) |
| | PPP4R2 | Serine/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1. (464 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (472 aa) |
| | CHEK2 | Serine/threonine-protein kinase Chk2 isoform X1. (544 aa) |
| | POLR2D | DNA-directed RNA polymerase II subunit RPB4. (142 aa) |
| | LOC102748477 | Spermatogenesis-associated protein 5-like; Belongs to the AAA ATPase family. (137 aa) |
| | YY1 | Transcriptional repressor protein YY1. (410 aa) |
| | TIMELESS | Protein timeless homolog. (1212 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | LOC102731077 | Fanconi anemia group I protein-like. (252 aa) |
| | POLR2E | DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1. (210 aa) |
| | EME1 | Crossover junction endonuclease EME1 isoform X1. (579 aa) |
| | GTF2H3 | General transcription factor IIH subunit 3. (162 aa) |
| | RCHY1 | RING finger and CHY zinc finger domain-containing protein 1 isoform X1. (261 aa) |
| | EYA4 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (646 aa) |
| | ACTR5 | Actin-related protein 5. (110 aa) |
| | KDM4A | Lysine-specific demethylase 4A. (480 aa) |
| | POLR2K | DNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa) |
| | LOC102737595 | Small ubiquitin-related modifier. (95 aa) |
| | ASCC2 | Activating signal cointegrator 1 complex subunit 2. (750 aa) |
| | FANCB | Fanconi anemia group B protein. (867 aa) |
| | SLC23A3 | Solute carrier family 23 member 3-like. (392 aa) |
| | TINF2 | LOW QUALITY PROTEIN: TERF1-interacting nuclear factor 2. (481 aa) |
| | CNPPD1 | Protein CNPPD1. (411 aa) |
| | ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa) |
| | TDP2 | tyrosyl-DNA phosphodiesterase 2. (358 aa) |
| | FANCG | Fanconi anemia group G protein. (626 aa) |
| | GTF2H5 | General transcription factor IIH subunit 5. (71 aa) |
| | VCP | Transitional endoplasmic reticulum ATPase isoform X1; Belongs to the AAA ATPase family. (806 aa) |
| | POLR2A | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa) |
| | OGG1 | N-glycosylase/DNA lyase isoform X2. (334 aa) |
| | FANCD2 | Fanconi anemia group D2 protein. (511 aa) |
| | LOC102726804 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa) |
| | RAD17 | Cell cycle checkpoint protein RAD17. (634 aa) |
| | LOC102748176 | Fanconi anemia-associated protein of 24 kDa. (224 aa) |
| | GTF2H2 | General transcription factor IIH subunit. (395 aa) |
| | SIRT6 | NAD-dependent protein deacetylase sirtuin-6. (359 aa) |
| | PIAS4 | E3 SUMO-protein ligase PIAS4. (503 aa) |
| | ERCC2 | TFIIH basal transcription factor complex helicase XPD subunit. (661 aa) |
| | ERCC1 | DNA excision repair protein ERCC-1. (293 aa) |
| | POLR2H | DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1. (114 aa) |
| | VWA5B2 | Von Willebrand factor A domain-containing protein 5B2. (1251 aa) |
| | COPS7A | COP9 signalosome complex subunit 7a isoform X1. (275 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (175 aa) |
| | LOC102738587 | Histone H2B subacrosomal variant-like; Belongs to the histone H2B family. (122 aa) |
| | TCEANC2 | Transcription elongation factor A N-terminal and central domain-containing protein 2. (208 aa) |
| | TCEA3 | Transcription elongation factor A protein 3. (74 aa) |
| | RCBTB1 | RCC1 and BTB domain-containing protein 1. (531 aa) |
| | FANCE | Fanconi anemia group E protein. (468 aa) |
| | BRCC3 | Lys-63-specific deubiquitinase BRCC36 isoform X1. (316 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (951 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1362 aa) |
| | LOC102738290 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | RAD18 | E3 ubiquitin-protein ligase RAD18. (500 aa) |
| | RNF4 | E3 ubiquitin-protein ligase RNF4. (190 aa) |
| | RPA3 | Replication protein A 14 kDa subunit. (121 aa) |
| | POLM | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (488 aa) |
| | LOC102735971 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (199 aa) |
| | LOC102732990 | Histone H2A; Belongs to the histone H2A family. (140 aa) |
| | POLD2 | DNA polymerase delta subunit 2. (469 aa) |
| | RNF111 | E3 ubiquitin-protein ligase Arkadia isoform X1. (994 aa) |
| | POLE4 | DNA polymerase epsilon subunit 4. (116 aa) |
| | LOC102728431 | Histone H2B; Belongs to the histone H2B family. (119 aa) |
| | LOC102750817 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC102746084 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | LOC102726286 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (78 aa) |
| | LOC102739804 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC102744317 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | LOC102742187 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | COPS2 | COP9 signalosome complex subunit 2 isoform X1. (450 aa) |
| | RAD1 | Cell cycle checkpoint protein RAD1. (281 aa) |
| | HELLS | Lymphoid-specific helicase isoform X1. (837 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | REV3L | DNA polymerase zeta catalytic subunit. (3024 aa) |
| | UBE2N | Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | WBP1 | WW domain-binding protein 1 isoform X1. (301 aa) |
| | INO80B | INO80 complex subunit B isoform X1. (356 aa) |
| | POLE3 | DNA polymerase epsilon subunit 3. (147 aa) |
| | RAD51C | DNA repair protein RAD51 homolog 3-like. (371 aa) |
| | LOC102741980 | Ubiquitin carboxyl-terminal hydrolase 10-like. (396 aa) |
| | SMARCA5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (1052 aa) |
| | KIAA0101 | PCNA-associated factor. (111 aa) |
| | RAD50 | DNA repair protein RAD50. (973 aa) |
| | RBBP8 | DNA endonuclease RBBP8. (758 aa) |
| | SUMO1 | Small ubiquitin-related modifier. (101 aa) |
| | LOC102735468 | Mediator of DNA damage checkpoint protein 1-like. (738 aa) |
| | LOC102733373 | Non-histone chromosomal protein HMG-14-like. (100 aa) |
| | LOC102729636 | polyubiquitin-B-like. (77 aa) |
| | COPS7B | COP9 signalosome complex subunit 7b isoform X2. (177 aa) |
| | SPOCD1 | SPOC domain-containing protein 1. (453 aa) |
| | UBE2V2 | Ubiquitin-conjugating enzyme E2 variant 2. (145 aa) |
| | SLX1A | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (274 aa) |
| | PPP4C | Serine/threonine-protein phosphatase. (307 aa) |
| | LOC102726582 | DNA-directed RNA polymerase II subunit RPB11-like isoform X1. (117 aa) |
| | LOC102725801 | Uroplakin-3b-like protein-like. (252 aa) |
| | LOC102731771 | Telomeric repeat-binding factor 2-interacting protein 1-like. (122 aa) |
| | WDR48 | WD repeat-containing protein 48 isoform X1. (677 aa) |
| | TMEM182 | Transmembrane protein 182. (229 aa) |
| | LOC102743906 | Nuclear transport factor 2-like. (127 aa) |
| | GEN1 | Flap endonuclease GEN homolog 1. (907 aa) |
| | USP1 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (783 aa) |
| | APBB1 | Amyloid beta A4 precursor protein-binding family B member 1 isoform X1. (710 aa) |
| | FTO | Alpha-ketoglutarate-dependent dioxygenase FTO. (549 aa) |
| | LOC102750322 | polyubiquitin-B-like. (153 aa) |
| | ISG15 | Ubiquitin-like protein ISG15. (169 aa) |
| | CLSPN | Claspin isoform X1. (1340 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | MPG | DNA-3-methyladenine glycosylase. (267 aa) |
| | POLQ | DNA polymerase theta. (2432 aa) |
| | PARP3 | Poly [ADP-ribose] polymerase. (532 aa) |
| | BAP1 | Ubiquitin carboxyl-terminal hydrolase. (729 aa) |
| | POLR2I | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa) |
| | LOC102728200 | ubiquitin-40S ribosomal protein S27a-like. (154 aa) |
| | LOC102743157 | Meiotic recombination protein REC114-like. (266 aa) |
| | APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (317 aa) |
| | NFRKB | Nuclear factor related to kappa-B-binding protein isoform X2. (1311 aa) |
| | PALB2 | Partner and localizer of BRCA2. (1183 aa) |
| | POLR2B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa) |
| | USP31 | Ubiquitin carboxyl-terminal hydrolase 31; Belongs to the peptidase C19 family. (1155 aa) |
| | CETN3 | Centrin-3 isoform X1. (167 aa) |
| | PARP2 | Poly [ADP-ribose] polymerase. (567 aa) |
| | LOC102727888 | COP9 signalosome complex subunit 3-like. (207 aa) |
| | RAD23A | UV excision repair protein RAD23 homolog A isoform X1. (363 aa) |
| | DDB1 | DNA damage-binding protein 1. (431 aa) |
| | USP45 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (816 aa) |
| | UBXN1 | UBX domain-containing protein 1 isoform X2. (295 aa) |
| | POLR2G | DNA-directed RNA polymerase II subunit RPB7. (172 aa) |
| | AQR | RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1491 aa) |
| | PIAS3 | E3 SUMO-protein ligase PIAS3. (628 aa) |
| | DDB2 | DNA damage-binding protein 2 isoform X1. (426 aa) |
| | TERF2 | Telomeric repeat-binding factor 2. (542 aa) |
| | EP300 | Histone acetyltransferase p300. (2425 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | LOC102732047 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (540 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1 isoform X3. (108 aa) |
| | TIPIN | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (184 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | TDRD3 | Tudor domain-containing protein 3-like isoform X1. (651 aa) |
| | KPNA2 | Importin subunit alpha; Functions in nuclear protein import. (529 aa) |
| | NEIL2 | Endonuclease 8-like 2. (334 aa) |
| | MCRS1 | Microspherule protein 1 isoform X2. (475 aa) |
| | POT1 | Protection of telomeres protein 1-like. (516 aa) |
| | MUTYH | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (519 aa) |
| | BRCA2 | Breast cancer type 2 susceptibility protein homolog. (2818 aa) |
| | FANCL | E3 ubiquitin-protein ligase FANCL isoform X1. (375 aa) |
| | RFC3 | Replication factor C subunit 3. (356 aa) |
| | DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2. (1061 aa) |
| | CDK2 | Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | DCLRE1B | 5' exonuclease Apollo. (538 aa) |
| | ERCC4 | DNA repair endonuclease XPF. (916 aa) |
| | UBE2L6 | ubiquitin/ISG15-conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa) |
| | NEIL3 | Endonuclease 8-like 3. (651 aa) |
| | ERCC6 | DNA excision repair protein ERCC-6. (457 aa) |
| | PARG | poly(ADP-ribose) glycohydrolase isoform X1. (977 aa) |
| | KCTD2 | BTB/POZ domain-containing protein KCTD2. (221 aa) |
| | CDK3 | Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | SUMO2 | Small ubiquitin-related modifier. (95 aa) |
| | ERCC8 | DNA excision repair protein ERCC-8 isoform X1. (396 aa) |
| | CCNH | cyclin-H-like; Belongs to the cyclin family. (344 aa) |
| | LOC102734720 | COP9 signalosome complex subunit 3-like. (247 aa) |
| | ASCC3 | Activating signal cointegrator 1 complex subunit 3. (2202 aa) |
| | LOC102746125 | LOW QUALITY PROTEIN: cyclin-A1-like; Belongs to the cyclin family. (463 aa) |
| | FANCM | Fanconi anemia group M protein. (2050 aa) |
| | PMS1 | PMS1 protein homolog 1 isoform X1. (929 aa) |
| | RFC5 | Replication factor C subunit 5 isoform X1. (340 aa) |
| | BABAM1 | BRISC and BRCA1-A complex member 1. (336 aa) |
| | UBE2T | Ubiquitin-conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (197 aa) |
| | ALKBH5 | RNA demethylase ALKBH5. (394 aa) |
| | LOC102733739 | DNA-directed RNA polymerase II subunit RPB3-like. (189 aa) |
| | ALKBH2 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2. (260 aa) |
| | LOC102732741 | uracil-DNA glycosylase-like. (177 aa) |
| | LOC102745317 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | INO80E | INO80 complex subunit E. (93 aa) |
| | LOC102750126 | Exonuclease 3'-5' domain-containing protein 2-like. (306 aa) |
| | LOC102744814 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (150 aa) |
| | LOC102739775 | Breast cancer type 1 susceptibility protein homolog. (471 aa) |
| | ATRIP | ATR-interacting protein. (597 aa) |
| | INO80 | DNA helicase INO80-like. (350 aa) |
| | LOC102733263 | Double-strand break repair protein MRE11A-like. (83 aa) |
| | LOC102747941 | Von Willebrand factor A domain-containing protein 5B1-like. (642 aa) |
| | LOC102733454 | DNA-(Apurinic or apyrimidinic site) lyase 2-like. (344 aa) |
| | LOC102743898 | Histone H2B type W-T-like; Belongs to the histone H2B family. (174 aa) |
| | TRIM47 | Tripartite motif-containing protein 47-like. (401 aa) |
| | LOC102740668 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (335 aa) |
| | SPRTN | sprT-like domain-containing protein Spartan. (484 aa) |
| | LOC102740374 | COP9 signalosome complex subunit 7b-like. (87 aa) |
| | LOC102746862 | ubiquitin-40S ribosomal protein S27a-like isoform X1. (156 aa) |
| | LOC102727091 | Transcription elongation factor A protein 3-like. (103 aa) |
| | COPS5 | LOW QUALITY PROTEIN: COP9 signalosome subunit 5. (334 aa) |
| | RPA4 | LOW QUALITY PROTEIN: replication protein A4, 30kDa. (262 aa) |
| | CUL4A | LOW QUALITY PROTEIN: cullin 4A; Belongs to the cullin family. (326 aa) |
| | ACD | LOW QUALITY PROTEIN: adrenocortical dysplasia homolog (Mouse). (494 aa) |
