STRINGSTRING
IKBKB IKBKB APP APP LOC102737114 LOC102737114 NKIRAS2 NKIRAS2 LOC102743429 LOC102743429 LRRC14 LRRC14 LOC102750659 LOC102750659 NKIRAS1 NKIRAS1 MAPK15 MAPK15 FOS FOS TONSL TONSL MAP2K3 MAP2K3 LOC102732719 LOC102732719 LOC102732031 LOC102732031 KXD1 KXD1 UBA52 UBA52 LOC102734131 LOC102734131 LOC102746732 LOC102746732 LOC102747337 LOC102747337 NLRP13 NLRP13 S100A12 S100A12 FNBP4 FNBP4 LRRC71 LRRC71 PELI3 PELI3 CASP8 CASP8 S100B S100B LOC102741653 LOC102741653 NFKB2 NFKB2 LOC102735556 LOC102735556 LOC102732364 LOC102732364 MAPK11 MAPK11 LOC102746862 LOC102746862 NLRP9 NLRP9 ATF7 ATF7 MAPK10 MAPK10 ECSIT ECSIT LOC102728200 LOC102728200 KIAA1468 KIAA1468 PPP2CB PPP2CB DUSP7 DUSP7 MAPK7 MAPK7 LOC102749246 LOC102749246 TMEM189 TMEM189 MAP2K6 MAP2K6 NFKBIA NFKBIA NFKB1 NFKB1 LOC102750322 LOC102750322 USP14 USP14 CREB1 CREB1 MAP2K7 MAP2K7 LOC102729636 LOC102729636 TAB3 TAB3 ATF1 ATF1 UBE2N UBE2N PELI2 PELI2 AGER AGER LOC102750157 LOC102750157 LOC102735971 LOC102735971 TNIP2 TNIP2 TRAF6 TRAF6 PPP2R5D PPP2R5D NOD1 NOD1 MAPK8 MAPK8 DUSP6 DUSP6 IKBKG IKBKG NFKBIB NFKBIB JUN JUN KHNYN KHNYN NLRX1 NLRX1 MAP3K1 MAP3K1 LOC102728244 LOC102728244 LOC102730470 LOC102730470 CHUK CHUK LOC102739213 LOC102739213 RPS6KA3 RPS6KA3 NLRP6 NLRP6 USP18 USP18 ATF2 ATF2 LOC102730779 LOC102730779 NOD2 NOD2 PPP4R1 PPP4R1 LRRC45 LRRC45 MAPK1 MAPK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
APPAmyloid beta A4 protein. (753 aa)
LOC102737114Leucine-rich repeat-containing protein 31-like. (211 aa)
NKIRAS2NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform X2. (191 aa)
LOC102743429Leucine-rich repeat-containing protein LOC400891-like. (392 aa)
LRRC14Leucine-rich repeat-containing protein 14. (503 aa)
LOC102750659Tonsoku-like protein-like. (490 aa)
NKIRAS1NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform X1. (192 aa)
MAPK15Mitogen-activated protein kinase. (559 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
TONSLTonsoku-like protein. (879 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
LOC102732719Ribosomal protein S6 kinase alpha-1-like. (200 aa)
LOC102732031Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like. (407 aa)
KXD1kxDL motif-containing protein 1 isoform X1. (176 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X3. (128 aa)
LOC102734131Fos-related antigen 2-like. (241 aa)
LOC102746732Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC102747337ubiquitin-40S ribosomal protein S27a-like. (154 aa)
NLRP13NACHT, LRR and PYD domains-containing protein 13. (991 aa)
S100A12Protein S100; Belongs to the S-100 family. (92 aa)
FNBP4Formin-binding protein 4 isoform X1. (1021 aa)
LRRC71Leucine-rich repeat-containing protein 71. (559 aa)
PELI3E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (468 aa)
CASP8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
LOC102741653Serine/threonine-protein phosphatase 4 regulatory subunit 1-like. (220 aa)
NFKB2Nuclear factor NF-kappa-B p100 subunit. (900 aa)
LOC102735556Mitogen-activated protein kinase 9-like. (134 aa)
LOC102732364Brorin-like. (133 aa)
MAPK11Mitogen-activated protein kinase. (254 aa)
LOC102746862ubiquitin-40S ribosomal protein S27a-like isoform X1. (156 aa)
NLRP9LOW QUALITY PROTEIN: NLR family, pyrin domain containing 9. (667 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7 isoform X2. (483 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
ECSITEvolutionarily conserved signaling intermediate in Toll pathway, mitochondrial. (409 aa)
LOC102728200ubiquitin-40S ribosomal protein S27a-like. (154 aa)
KIAA1468lisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X1. (1214 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (406 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
LOC102749246Ubiquitin-conjugating enzyme E2 variant 1-like isoform X2. (147 aa)
TMEM189Transmembrane protein 189. (221 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
NFKBIANF-kappa-B inhibitor alpha isoform X2. (314 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (254 aa)
LOC102750322polyubiquitin-B-like. (153 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (494 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
LOC102729636polyubiquitin-B-like. (77 aa)
TAB3TGF-beta-activated kinase 1 and MAP3K7-binding protein 3-like. (717 aa)
ATF1Cyclic AMP-dependent transcription factor ATF-1 isoform X2. (270 aa)
UBE2NUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
PELI2E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa)
AGERAdvanced glycosylation end product-specific receptor. (397 aa)
LOC102750157Leucine-rich repeat-containing protein 31-like. (523 aa)
LOC102735971Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
TNIP2TNFAIP3-interacting protein 2. (432 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (676 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (953 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
IKBKGNF-kappa-B essential modulator isoform X2. (419 aa)
NFKBIBNF-kappa-B inhibitor beta isoform X2. (354 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
KHNYNProtein KHNYN. (668 aa)
NLRX1NLR family member X1. (975 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1345 aa)
LOC102728244Interleukin-1 receptor-associated kinase 1-like. (299 aa)
LOC102730470Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
LOC102739213High mobility group protein B1-like. (214 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
NLRP6NACHT, LRR and PYD domains-containing protein 6. (893 aa)
USP18Ubl carboxyl-terminal hydrolase 18; Belongs to the peptidase C19 family. (370 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
LOC102730779Coiled-coil domain-containing protein 71L-like. (112 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2. (1013 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1. (367 aa)
LRRC45Leucine-rich repeat-containing protein 45. (670 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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