(11 nodes) (2018) C9orf72, a protein associated with amyotrophic lateral sclerosis (ALS) is a guanine nucleotide exchange factor. network (Leptonychotes weddellii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	CDC42	Cell division control protein 42 homolog. (160 aa)
	TXN	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	LOC102743896	Thioredoxin; Belongs to the thioredoxin family. (121 aa)
	SUMO1	Small ubiquitin-related modifier. (101 aa)
	LOC102737595	Small ubiquitin-related modifier. (95 aa)
	SUMO2	Small ubiquitin-related modifier. (95 aa)
	ALB	Serum albumin. (608 aa)
	RAB7A	Ras-related protein Rab-7a isoform X1. (207 aa)
	SMCR8	smith-Magenis syndrome chromosomal region candidate gene 8 protein. (937 aa)
	SUMO3	Small ubiquitin-related modifier. (111 aa)
	FLCN	Folliculin. (579 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	CDC42	A0A2U3XEF9	A0A2U3YLC1	Serum albumin.	Cell division control protein 42 homolog.	0.478
ALB	SUMO1	A0A2U3XEF9	A0A2U3XT97	Serum albumin.	Small ubiquitin-related modifier.	0.487
ALB	TXN	A0A2U3XEF9	A0A2U3YK60	Serum albumin.	Thioredoxin; Belongs to the thioredoxin family.	0.595
CDC42	ALB	A0A2U3YLC1	A0A2U3XEF9	Cell division control protein 42 homolog.	Serum albumin.	0.478
CDC42	RAB7A	A0A2U3YLC1	A0A2U3YFG6	Cell division control protein 42 homolog.	Ras-related protein Rab-7a isoform X1.	0.485
FLCN	SMCR8	A0A2U3YLS2	A0A2U3Z146	Folliculin.	smith-Magenis syndrome chromosomal region candidate gene 8 protein.	0.769
LOC102737595	SUMO1	A0A2U3Y8B4	A0A2U3XT97	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.914
LOC102737595	TXN	A0A2U3Y8B4	A0A2U3YK60	Small ubiquitin-related modifier.	Thioredoxin; Belongs to the thioredoxin family.	0.474
LOC102743896	TXN	A0A2U3XJV3	A0A2U3YK60	Thioredoxin; Belongs to the thioredoxin family.	Thioredoxin; Belongs to the thioredoxin family.	0.713
RAB7A	CDC42	A0A2U3YFG6	A0A2U3YLC1	Ras-related protein Rab-7a isoform X1.	Cell division control protein 42 homolog.	0.485
SMCR8	FLCN	A0A2U3Z146	A0A2U3YLS2	smith-Magenis syndrome chromosomal region candidate gene 8 protein.	Folliculin.	0.769
SUMO1	ALB	A0A2U3XT97	A0A2U3XEF9	Small ubiquitin-related modifier.	Serum albumin.	0.487
SUMO1	LOC102737595	A0A2U3XT97	A0A2U3Y8B4	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.914
SUMO1	SUMO2	A0A2U3XT97	A0A2U3X9G7	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.914
SUMO1	SUMO3	A0A2U3XT97	A0A2U3YTI9	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.914
SUMO1	TXN	A0A2U3XT97	A0A2U3YK60	Small ubiquitin-related modifier.	Thioredoxin; Belongs to the thioredoxin family.	0.528
SUMO2	SUMO1	A0A2U3X9G7	A0A2U3XT97	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.914
SUMO2	TXN	A0A2U3X9G7	A0A2U3YK60	Small ubiquitin-related modifier.	Thioredoxin; Belongs to the thioredoxin family.	0.474
SUMO3	SUMO1	A0A2U3YTI9	A0A2U3XT97	Small ubiquitin-related modifier.	Small ubiquitin-related modifier.	0.914
SUMO3	TXN	A0A2U3YTI9	A0A2U3YK60	Small ubiquitin-related modifier.	Thioredoxin; Belongs to the thioredoxin family.	0.474