34 items (Leptonychotes weddellii) - STRING interaction network

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Your Input:
	USP8	Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family. (1116 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	UBE2L3	Ubiquitin-conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
	SIRT4	NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
	SUMO3	Small ubiquitin-related modifier. (111 aa)
	AMBRA1	Activating molecule in BECN1-regulated autophagy protein 1-like. (299 aa)
	USP35	Ubiquitin carboxyl-terminal hydrolase 35-like; Belongs to the peptidase C19 family. (571 aa)
	VPS11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	VDAC2	Voltage-dependent anion-selective channel protein 2 isoform X1. (294 aa)
	PPEF1	Serine/threonine-protein phosphatase. (519 aa)
	VPS18	Vacuolar protein sorting-associated protein 18 homolog. (895 aa)
	NBR1	Next to BRCA1 gene 1 protein. (948 aa)
	STX17	Syntaxin-17; Belongs to the syntaxin family. (302 aa)
	USP15	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
	LOC102737595	Small ubiquitin-related modifier. (95 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (255 aa)
	GABARAP	Gamma-aminobutyric acid receptor-associated protein. (117 aa)
	PINK1	Serine/threonine-protein kinase PINK1, mitochondrial. (488 aa)
	MUL1	Mitochondrial ubiquitin ligase activator of NFKB 1. (352 aa)
	BAK1	Bcl-2 homologous antagonist/killer. (211 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
	UBE2N	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	SUMO1	Small ubiquitin-related modifier. (101 aa)
	PPP4C	Serine/threonine-protein phosphatase. (307 aa)
	SRC	Tyrosine-protein kinase. (536 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	USP33	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (904 aa)
	VPS16	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (308 aa)
	FOXO3	Forkhead box protein O3. (672 aa)
	TFEB	Transcription factor EB. (329 aa)
	SUMO2	Small ubiquitin-related modifier. (95 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBRA1	ATG12	A0A2U3YWA7	A0A2U3XZP0	Activating molecule in BECN1-regulated autophagy protein 1-like.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.620
AMBRA1	ATG5	A0A2U3YWA7	A0A2U3Y6R5	Activating molecule in BECN1-regulated autophagy protein 1-like.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.499
ATG12	AMBRA1	A0A2U3XZP0	A0A2U3YWA7	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Activating molecule in BECN1-regulated autophagy protein 1-like.	0.620
ATG12	ATG5	A0A2U3XZP0	A0A2U3Y6R5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	GABARAP	A0A2U3XZP0	A0A2U3Y5T4	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Gamma-aminobutyric acid receptor-associated protein.	0.942
ATG12	NBR1	A0A2U3XZP0	A0A2U3Z4C3	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Next to BRCA1 gene 1 protein.	0.875
ATG12	PINK1	A0A2U3XZP0	A0A2U3Y3N8	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Serine/threonine-protein kinase PINK1, mitochondrial.	0.546
ATG12	STX17	A0A2U3XZP0	A0A2U3YBR1	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Syntaxin-17; Belongs to the syntaxin family.	0.552
ATG12	TFEB	A0A2U3XZP0	A0A2U3XD63	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Transcription factor EB.	0.472
ATG12	VDAC2	A0A2U3XZP0	A0A2U3Z1R3	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Voltage-dependent anion-selective channel protein 2 isoform X1.	0.564
ATG5	AMBRA1	A0A2U3Y6R5	A0A2U3YWA7	Autophagy protein 5; Involved in autophagic vesicle formation.	Activating molecule in BECN1-regulated autophagy protein 1-like.	0.499
ATG5	ATG12	A0A2U3Y6R5	A0A2U3XZP0	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG5	FOXO3	A0A2U3Y6R5	A0A2U3XDW8	Autophagy protein 5; Involved in autophagic vesicle formation.	Forkhead box protein O3.	0.460
ATG5	GABARAP	A0A2U3Y6R5	A0A2U3Y5T4	Autophagy protein 5; Involved in autophagic vesicle formation.	Gamma-aminobutyric acid receptor-associated protein.	0.917
ATG5	NBR1	A0A2U3Y6R5	A0A2U3Z4C3	Autophagy protein 5; Involved in autophagic vesicle formation.	Next to BRCA1 gene 1 protein.	0.848
ATG5	PINK1	A0A2U3Y6R5	A0A2U3Y3N8	Autophagy protein 5; Involved in autophagic vesicle formation.	Serine/threonine-protein kinase PINK1, mitochondrial.	0.589
ATG5	PTEN	A0A2U3Y6R5	A0A2U3XMX7	Autophagy protein 5; Involved in autophagic vesicle formation.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.449
ATG5	STX17	A0A2U3Y6R5	A0A2U3YBR1	Autophagy protein 5; Involved in autophagic vesicle formation.	Syntaxin-17; Belongs to the syntaxin family.	0.761
ATG5	TFEB	A0A2U3Y6R5	A0A2U3XD63	Autophagy protein 5; Involved in autophagic vesicle formation.	Transcription factor EB.	0.637
ATG5	VDAC2	A0A2U3Y6R5	A0A2U3Z1R3	Autophagy protein 5; Involved in autophagic vesicle formation.	Voltage-dependent anion-selective channel protein 2 isoform X1.	0.492