STRINGSTRING
LOC102730129 LOC102730129 LOC102739283 LOC102739283 AP5S1 AP5S1 LOC102742177 LOC102742177 MAPK11 MAPK11 LOC102734470 LOC102734470 LOC102733359 LOC102733359 PRKACA PRKACA LOC102735556 LOC102735556 LOC102750801 LOC102750801 NFKB2 NFKB2 TIE1 TIE1 LOC102744822 LOC102744822 JUND JUND VEGFB VEGFB PPM1B PPM1B FLT3 FLT3 ANGPT4 ANGPT4 CACNG2 CACNG2 NFATC1 NFATC1 RASGRF1 RASGRF1 LOC102736718 LOC102736718 LOC102733219 LOC102733219 PGF PGF FOS FOS CSF1 CSF1 LOC102725641 LOC102725641 RASGRP2 RASGRP2 CCDC88B CCDC88B FGF18 FGF18 FGF4 FGF4 SOS1 SOS1 FGF3 FGF3 LOC102737823 LOC102737823 LOC102729273 LOC102729273 IL1A IL1A MEF2C MEF2C IL1B IL1B CASP3 CASP3 FGF17 FGF17 CRKL CRKL MST1 MST1 LOC102747801 LOC102747801 CDC42 CDC42 RRAS RRAS MKNK2 MKNK2 IKBKB IKBKB MAPK1 MAPK1 CACNB1 CACNB1 LRRC45 LRRC45 MAP3K6 MAP3K6 PAK2 PAK2 CDC25B CDC25B RASGRP1 RASGRP1 CACNA2D4 CACNA2D4 RAC2 RAC2 ATF2 ATF2 LOC102731583 LOC102731583 RPS6KA3 RPS6KA3 CSF1R CSF1R TRADD TRADD CRK CRK DUSP8 DUSP8 MOB2 MOB2 ANGPT2 ANGPT2 CHUK CHUK LOC102727336 LOC102727336 MSANTD3 MSANTD3 MAP3K3 MAP3K3 TAOK1 TAOK1 LOC102726429 LOC102726429 CACNA1G CACNA1G LOC102730470 LOC102730470 DUSP9 DUSP9 LOC102728244 LOC102728244 MAP3K1 MAP3K1 LOC102736999 LOC102736999 RAF1 RAF1 RAP1B RAP1B AKT3 AKT3 VEGFC VEGFC RAPGEF2 RAPGEF2 LOC102749673 LOC102749673 PAK1 PAK1 JUN JUN FLNA FLNA MAP4K1 MAP4K1 IKBKG IKBKG LOC102741496 LOC102741496 NTRK2 NTRK2 NGF NGF KITLG KITLG DUSP6 DUSP6 TP53 TP53 FGFR2 FGFR2 MAP2K2 MAP2K2 MPP3 MPP3 MAX MAX HSPA2 HSPA2 LOC102734190 LOC102734190 TNF TNF HSPA1L HSPA1L ERAS ERAS CACNA1F CACNA1F AKT1 AKT1 IGF1R IGF1R TGFB2 TGFB2 MAPK8 MAPK8 DUSP1 DUSP1 TNFRSF1A TNFRSF1A SUCO SUCO FASLG FASLG MAP4K4 MAP4K4 MKNK1 MKNK1 FGF5 FGF5 LOC102750346 LOC102750346 CACNG6 CACNG6 CACNG7 CACNG7 TEK TEK ELK4 ELK4 PRKACB PRKACB PTK7 PTK7 LOC102728321 LOC102728321 RIT1 RIT1 SRF SRF FGFR3 FGFR3 JMJD7 JMJD7 TRAF6 TRAF6 CACNB2 CACNB2 NTF3 NTF3 MAP3K14 MAP3K14 LOC102747671 LOC102747671 LOC102747961 LOC102747961 MAP3K8 MAP3K8 GALK2 GALK2 FGF7 FGF7 ANGPTL7 ANGPTL7 NPM1 NPM1 GADD45A GADD45A MAPK8IP2 MAPK8IP2 MAPK12 MAPK12 STK4 STK4 LAMTOR3 LAMTOR3 LOC102745453 LOC102745453 LOC102745146 LOC102745146 ADAM15 ADAM15 EFNA1 EFNA1 ADAM21 ADAM21 LOC102734779 LOC102734779 MAPT MAPT MAP3K4 MAP3K4 TGFBR2 TGFBR2 HSPB1 HSPB1 MAP2K7 MAP2K7 MAP3K13 MAP3K13 FGFR4 FGFR4 NFKB1 NFKB1 PTPRR PTPRR MAP2K6 MAP2K6 RRAD RRAD ADAM18 ADAM18 LOC102740164 LOC102740164 MAPK7 MAPK7 ADAM32 ADAM32 ADAM2 ADAM2 PLA2G4D PLA2G4D DUSP7 DUSP7 ANGPT1 ANGPT1 NLK NLK IGF1 IGF1 LOC102740357 LOC102740357 FGF8 FGF8 ECSIT ECSIT LOC102728392 LOC102728392 IRAK4 IRAK4 STK3 STK3 NFATC3 NFATC3 GNA12 GNA12 PPP3R1 PPP3R1 LOC102741253 LOC102741253 EPGN EPGN ATF4 ATF4 GEM GEM EREG EREG MAP2K1 MAP2K1 MAPK10 MAPK10 FGF10 FGF10 ADAM7 ADAM7 ADAM22 ADAM22 CACNG4 CACNG4 CACNG1 CACNG1 CACNG5 CACNG5 LOC102727364 LOC102727364 LOC102742552 LOC102742552 CACNB3 CACNB3 LOC102739252 LOC102739252 MAP3K12 MAP3K12 ERBB3 ERBB3 ATF7 ATF7 CSDE1 CSDE1 NRAS NRAS MAP4K3 MAP4K3 TGFA TGFA LOC102731213 LOC102731213 MRAS MRAS TMEFF2 TMEFF2 FGF9 FGF9 RASA1 RASA1 TMEFF1 TMEFF1 KRAS KRAS PPP3R2 PPP3R2 PDGFRL PDGFRL REM1 REM1 FGF20 FGF20 PDGFC PDGFC CACNA2D1 CACNA2D1 HGF HGF RPS6KA6 RPS6KA6 FGF16 FGF16 MAP2K3 MAP2K3 LOC102732719 LOC102732719 PTPN5 PTPN5 FGFRL1 FGFRL1 PDGFB PDGFB MAP3K2 MAP3K2 LOC102737030 LOC102737030 GADD45G GADD45G LOC102735329 LOC102735329 PDGFRA PDGFRA FGF21 FGF21 TGFB1 TGFB1 RBM4B RBM4B TGFB3 TGFB3 STMN1 STMN1 LOC102738241 LOC102738241 CATSPER4 CATSPER4 LOC102737749 LOC102737749 ADAM30 ADAM30 NTRK1 NTRK1 LOC102732653 LOC102732653 FLT3LG FLT3LG LOC102740953 LOC102740953 PTPN7 PTPN7 GADD45B GADD45B LOC102731850 LOC102731850 LOC102740057 LOC102740057 NF1 NF1 FGF6 FGF6 FGF23 FGF23 LOC102728502 LOC102728502 MYD88 MYD88 LOC102745745 LOC102745745 FGF2 FGF2 INS INS IGF2 IGF2 NTF4 NTF4 LOC102748147 LOC102748147 DDIT3 DDIT3 FGF22 FGF22 LOC102750700 LOC102750700 SLC39A12 SLC39A12 MAPK8IP1 MAPK8IP1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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LOC102730129Uncharacterized protein LOC102730129. (471 aa)
LOC102739283Heat shock cognate 71 kDa protein-like. (196 aa)
AP5S1AP-5 complex subunit sigma-1 isoform X1. (200 aa)
LOC102742177Mast/stem cell growth factor receptor Kit-like. (217 aa)
MAPK11Mitogen-activated protein kinase. (254 aa)
LOC102734470ETS domain-containing protein Elk-3-like. (237 aa)
LOC102733359ephrin-A4-like; Belongs to the ephrin family. (166 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC102735556Mitogen-activated protein kinase 9-like. (134 aa)
LOC102750801filamin-C-like. (2247 aa)
NFKB2Nuclear factor NF-kappa-B p100 subunit. (900 aa)
TIE1Tyrosine-protein kinase receptor Tie-1. (1015 aa)
LOC102744822Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins [...] (56 aa)
JUNDTranscription factor jun-D. (298 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
PPM1BProtein phosphatase 1B isoform X2. (479 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (984 aa)
ANGPT4Angiopoietin-4. (498 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (252 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1. (221 aa)
RASGRF1Ras-specific guanine nucleotide-releasing factor 1. (1165 aa)
LOC102736718Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC102733219Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (147 aa)
PGFPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (547 aa)
LOC102725641Ubiquitin carboxyl-terminal hydrolase 12-B-like; Belongs to the peptidase C19 family. (251 aa)
RASGRP2RAS guanyl-releasing protein 2 isoform X2. (608 aa)
CCDC88BCoiled-coil domain-containing protein 88B. (1465 aa)
FGF18Fibroblast growth factor 18. (116 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (172 aa)
SOS1Son of sevenless homolog 1-like. (281 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
LOC102737823Fibroblast growth factor 19-like; Belongs to the heparin-binding growth factors family. (115 aa)
LOC102729273GTP-binding protein Rit2-like isoform X1. (217 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (265 aa)
MEF2CMyocyte-specific enhancer factor 2C-like isoform X2. (473 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (270 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (302 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
CRKLCrk-like protein. (303 aa)
MST1Hepatocyte growth factor-like protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (711 aa)
LOC102747801Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
CDC42Cell division control protein 42 homolog. (160 aa)
RRASRas-related protein R-Ras. (218 aa)
MKNK2MAP kinase-interacting serine/threonine-protein kinase 2 isoform X2; Belongs to the protein kinase superfamily. (463 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
CACNB1Voltage-dependent L-type calcium channel subunit beta-1 isoform X1. (643 aa)
LRRC45Leucine-rich repeat-containing protein 45. (670 aa)
MAP3K6Mitogen-activated protein kinase kinase kinase 6. (1204 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
CDC25BM-phase inducer phosphatase 2 isoform X1. (516 aa)
RASGRP1RAS guanyl-releasing protein 1-like isoform X1. (366 aa)
CACNA2D4Voltage-dependent calcium channel subunit alpha-2/delta-4. (1102 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
LOC102731583Voltage-dependent calcium channel gamma-3 subunit-like. (315 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (312 aa)
CRKAdapter molecule crk. (92 aa)
DUSP8Dual specificity protein phosphatase 8. (394 aa)
MOB2MOB kinase activator 2. (266 aa)
ANGPT2Angiopoietin-2 isoform X1. (495 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
LOC102727336Voltage-dependent calcium channel subunit alpha-2/delta-3-like. (239 aa)
MSANTD3myb/SANT-like DNA-binding domain-containing protein 3. (275 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (600 aa)
TAOK1Serine/threonine-protein kinase TAO1. (956 aa)
LOC102726429MDS1 and EVI1 complex locus protein EVI1-like. (184 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2266 aa)
LOC102730470Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (380 aa)
LOC102728244Interleukin-1 receptor-associated kinase 1-like. (299 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1345 aa)
LOC102736999Dual specificity protein phosphatase 10-like; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (177 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2 isoform X1. (1499 aa)
LOC102749673Insulin-like growth factor 1 receptor-like. (143 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
FLNAfilamin-A-like. (1685 aa)
MAP4K1Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa)
IKBKGNF-kappa-B essential modulator isoform X2. (419 aa)
LOC102741496BDNF/NT-3 growth factors receptor-like. (97 aa)
NTRK2BDNF/NT-3 growth factors receptor-like. (420 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
FGFR2Fibroblast growth factor receptor 2. (658 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
MPP3MAGUK p55 subfamily member 3; Belongs to the MAGUK family. (585 aa)
MAXProtein max isoform X1. (160 aa)
HSPA2Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (636 aa)
LOC102734190Heat shock 70 kDa protein 1-like; Belongs to the heat shock protein 70 family. (641 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
HSPA1LHeat shock 70 kDa protein 1-like; Belongs to the heat shock protein 70 family. (641 aa)
ERASGTPase ERas. (233 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1983 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
IGF1RInsulin-like growth factor 1 receptor-like. (291 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (358 aa)
SUCOSUN domain-containing ossification factor. (983 aa)
FASLGTumor necrosis factor ligand superfamily member 6. (130 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1251 aa)
MKNK1MAP kinase-interacting serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (415 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (275 aa)
LOC102750346Death domain-containing membrane protein NRADD-like. (250 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
ELK4ETS domain-containing protein Elk-4. (430 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
PTK7Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
LOC102728321High affinity nerve growth factor receptor-like. (109 aa)
RIT1GTP-binding protein Rit1. (219 aa)
SRFSerum response factor. (508 aa)
FGFR3Fibroblast growth factor receptor. (809 aa)
JMJD7jmjC domain-containing protein 7. (316 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (613 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (257 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (955 aa)
LOC102747671Disintegrin and metalloproteinase domain-containing protein 1a-like. (741 aa)
LOC102747961Disintegrin and metalloproteinase domain-containing protein 1a-like. (758 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (467 aa)
GALK2N-acetylgalactosamine kinase. (332 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
ANGPTL7Angiopoietin-related protein 7. (344 aa)
NPM1Nucleophosmin isoform X1. (294 aa)
GADD45AGrowth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa)
MAPK8IP2c-Jun-amino-terminal kinase-interacting protein 2. (831 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
STK4Serine/threonine-protein kinase 4. (487 aa)
LAMTOR3Ragulator complex protein LAMTOR3. (111 aa)
LOC102745453SUN domain-containing ossification factor-like. (283 aa)
LOC102745146Tumor necrosis factor ligand superfamily member 6-like; Belongs to the tumor necrosis factor family. (173 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (867 aa)
EFNA1ephrin-A1 isoform X1; Belongs to the ephrin family. (205 aa)
ADAM21Disintegrin and metalloproteinase domain-containing protein 21. (720 aa)
LOC102734779Disintegrin and metalloproteinase domain-containing protein 20-like. (724 aa)
MAPTMicrotubule-associated protein. (796 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4 isoform X1. (1605 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (207 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
FGFR4Fibroblast growth factor receptor. (800 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (254 aa)
PTPRRReceptor-type tyrosine-protein phosphatase R isoform X1. (655 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
ADAM18Disintegrin and metalloproteinase domain-containing protein 18-like. (838 aa)
LOC102740164Disintegrin and metalloproteinase domain-containing protein 18-like. (761 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
ADAM32Disintegrin and metalloproteinase domain-containing protein 32. (721 aa)
ADAM2Disintegrin and metalloproteinase domain-containing protein 2. (731 aa)
PLA2G4DPhospholipase A2. (817 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (406 aa)
ANGPT1Angiopoietin-1 isoform X1. (402 aa)
NLKSerine/threonine-protein kinase NLK. (507 aa)
IGF1Insulin-like growth factor I isoform X1. (153 aa)
LOC102740357Cell division control protein 42 homolog. (191 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
ECSITEvolutionarily conserved signaling intermediate in Toll pathway, mitochondrial. (409 aa)
LOC102728392ephrin-A5-like; Belongs to the ephrin family. (191 aa)
IRAK4Interleukin-1 receptor-associated kinase 4 isoform X1. (459 aa)
STK3Serine/threonine-protein kinase 3 isoform X1. (491 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1075 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12 isoform X1. (305 aa)
PPP3R1Calcineurin subunit B type 1 isoform X1. (170 aa)
LOC102741253Amphiregulin-like. (253 aa)
EPGNEpigen isoform X1. (153 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
EREGProepiregulin. (292 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
ADAM7Disintegrin and metalloproteinase domain-containing protein 7. (831 aa)
ADAM22Disintegrin and metalloproteinase domain-containing protein 22. (464 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
LOC102727364Disintegrin and metalloproteinase domain-containing protein 29-like. (817 aa)
LOC102742552Platelet-derived growth factor D-like isoform X1. (370 aa)
CACNB3Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (484 aa)
LOC102739252Heat shock cognate 71 kDa protein-like. (395 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7 isoform X2. (483 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
NRASGTPase NRas. (189 aa)
MAP4K3Non-specific serine/threonine protein kinase; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (894 aa)
TGFAProtransforming growth factor alpha. (160 aa)
LOC102731213Heat shock cognate 71 kDa protein-like isoform X1; Belongs to the heat shock protein 70 family. (646 aa)
MRASRas-related protein M-Ras. (208 aa)
TMEFF2Tomoregulin-2-like isoform X1. (374 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
RASA1Ras GTPase-activating protein 1. (1039 aa)
TMEFF1Tomoregulin-1. (230 aa)
KRASGTPase KRas isoform X2. (188 aa)
PPP3R2Calcineurin subunit B type 2. (170 aa)
PDGFRLPlatelet-derived growth factor receptor-like protein. (387 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
PDGFCPlatelet-derived growth factor C-like; Belongs to the PDGF/VEGF growth factor family. (345 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1. (1091 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
RPS6KA6Ribosomal protein S6 kinase. (744 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
LOC102732719Ribosomal protein S6 kinase alpha-1-like. (200 aa)
PTPN5Tyrosine-protein phosphatase non-receptor type 5 isoform X1. (539 aa)
FGFRL1Fibroblast growth factor receptor-like 1. (508 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (540 aa)
LOC102737030Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. (627 aa)
GADD45GGrowth arrest and DNA damage-inducible protein GADD45 gamma. (159 aa)
LOC102735329Vascular endothelial growth factor receptor 1-like. (351 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1090 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
TGFB1Transforming growth factor beta-1. (261 aa)
RBM4BRNA-binding protein 4B isoform X1. (359 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
STMN1Stathmin; Belongs to the stathmin family. (149 aa)
LOC102738241Mitogen-activated protein kinase kinase kinase 5-like. (795 aa)
CATSPER4Cation channel sperm-associated protein 4. (337 aa)
LOC102737749Transcription factor RelB-like. (167 aa)
ADAM30Disintegrin and metalloproteinase domain-containing protein 30. (734 aa)
NTRK1Tyrosine-protein kinase receptor. (592 aa)
LOC102732653Nuclear receptor subfamily 4 group A member 1-like. (306 aa)
FLT3LGFms-related tyrosine kinase 3 ligand. (290 aa)
LOC102740953MDS1 and EVI1 complex locus protein EVI1-like isoform X2. (867 aa)
PTPN7Tyrosine-protein phosphatase non-receptor type 7. (301 aa)
GADD45BGrowth arrest and DNA damage-inducible protein GADD45 beta isoform X2. (160 aa)
LOC102731850Tyrosine-protein kinase receptor. (757 aa)
LOC102740057Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (186 aa)
NF1Neurofibromin-like. (1269 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (182 aa)
FGF23Fibroblast growth factor 23. (177 aa)
LOC102728502Serine/threonine-protein kinase TAO2-like. (822 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (296 aa)
LOC102745745Tyrosine-protein kinase receptor. (302 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
IGF2Insulin-like growth factor II. (138 aa)
NTF4Neurotrophin-4; Belongs to the NGF-beta family. (211 aa)
LOC102748147Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
LOC102750700Disintegrin and metalloproteinase domain-containing protein 21-like. (745 aa)
SLC39A12Zinc transporter ZIP12. (366 aa)
MAPK8IP1c-Jun-amino-terminal kinase-interacting protein 1. (669 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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