STRINGSTRING
GSK3B GSK3B CRK CRK MSANTD3 MSANTD3 RPS6KB1 RPS6KB1 REM1 REM1 KRAS KRAS TMEFF1 TMEFF1 TMEFF2 TMEFF2 NCK1 NCK1 LOC102726446 LOC102726446 TGFA TGFA CBLB CBLB NRAS NRAS CSDE1 CSDE1 ERBB3 ERBB3 PIK3R3 PIK3R3 MAPK10 MAPK10 MAP2K1 MAP2K1 EREG EREG LOC102734470 LOC102734470 LOC102731864 LOC102731864 LOC102751021 LOC102751021 GEM GEM EPGN EPGN LOC102741253 LOC102741253 LOC102749335 LOC102749335 HBEGF HBEGF LOC102740565 LOC102740565 RRAD RRAD PAK7 PAK7 CDKN1B CDKN1B CAMK2G CAMK2G SRC SRC MAP2K7 MAP2K7 ALKBH4 ALKBH4 LOC102745868 LOC102745868 NRG1 NRG1 SHC1 SHC1 GAB1 GAB1 MTOR MTOR RAF1 RAF1 SHC4 SHC4 CEP152 CEP152 MAPK8 MAPK8 AKT1 AKT1 ERAS ERAS STAT5B STAT5B MAP2K2 MAP2K2 PAK4 PAK4 JUN JUN PAK1 PAK1 CBL CBL AKT3 AKT3 RPS6KB2 RPS6KB2 LOC102735556 LOC102735556 CDKN1A CDKN1A ARSI ARSI CAMK2A CAMK2A LOC102728297 LOC102728297 STAT5A STAT5A LOC102741259 LOC102741259 PAK6 PAK6 ABL1 ABL1 NCK2 NCK2 LOC102736516 LOC102736516 LOC102737030 LOC102737030 PIK3CA PIK3CA PIK3CD PIK3CD SOS1 SOS1 CRKL CRKL LOC102735415 LOC102735415 MAPK1 MAPK1 PAK2 PAK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
CRKAdapter molecule crk. (92 aa)
MSANTD3myb/SANT-like DNA-binding domain-containing protein 3. (275 aa)
RPS6KB1Non-specific serine/threonine protein kinase. (445 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
KRASGTPase KRas isoform X2. (188 aa)
TMEFF1Tomoregulin-1. (230 aa)
TMEFF2Tomoregulin-2-like isoform X1. (374 aa)
NCK1Cytoplasmic protein. (377 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
TGFAProtransforming growth factor alpha. (160 aa)
CBLBE3 ubiquitin-protein ligase CBL-B-like. (832 aa)
NRASGTPase NRas. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
EREGProepiregulin. (292 aa)
LOC102734470ETS domain-containing protein Elk-3-like. (237 aa)
LOC102731864Signal transducer and activator of transcription 5B-like. (353 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
EPGNEpigen isoform X1. (153 aa)
LOC102741253Amphiregulin-like. (253 aa)
LOC102749335E3 ubiquitin-protein ligase CBL-B-like. (139 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
LOC102740565Pro-neuregulin-2, membrane-bound isoform-like. (410 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
PAK7Serine/threonine-protein kinase PAK 7. (474 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (574 aa)
SRCTyrosine-protein kinase. (536 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
ALKBH4Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4. (302 aa)
LOC102745868Pro-neuregulin-1, membrane-bound isoform-like. (92 aa)
NRG1Pro-neuregulin-3, membrane-bound isoform-like isoform X1. (694 aa)
SHC1SHC-transforming protein 1 isoform X2. (583 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (724 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
SHC4SHC-transforming protein 4. (630 aa)
CEP152Centrosomal protein of 152 kDa isoform X1. (1723 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
ERASGTPase ERas. (233 aa)
STAT5BSignal transducer and activator of transcription 5B. (508 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
PAK4Non-specific serine/threonine protein kinase. (441 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
LOC102735556Mitogen-activated protein kinase 9-like. (134 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (161 aa)
ARSIArylsulfatase I. (575 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (476 aa)
LOC102728297Serine/threonine-protein kinase PAK 7-like. (225 aa)
STAT5ASignal transducer and activator of transcription 5A. (464 aa)
LOC102741259Serine/threonine-protein kinase PAK 3-like. (339 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
ABL1Tyrosine-protein kinase ABL1-like. (312 aa)
NCK2Cytoplasmic protein. (380 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
LOC102737030Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. (627 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
SOS1Son of sevenless homolog 1-like. (281 aa)
CRKLCrk-like protein. (303 aa)
LOC102735415Phosphoinositide phospholipase C. (309 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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