STRINGSTRING
PGK1 PGK1 PGK2 PGK2 ALDOB ALDOB LOC102726446 LOC102726446 ARNT ARNT LOC102740749 LOC102740749 LDHB LDHB PIK3R3 PIK3R3 MAP2K1 MAP2K1 RBX1 RBX1 EP300 EP300 IGF1 IGF1 ALDOC ALDOC LOC102751010 LOC102751010 ANGPT1 ANGPT1 TIMP1 TIMP1 NFKB1 NFKB1 LOC102729427 LOC102729427 CDKN1B CDKN1B HK3 HK3 EIF4E1B EIF4E1B CAMK2G CAMK2G SERPINE1 SERPINE1 ZAN ZAN ENO1 ENO1 PFKFB3 PFKFB3 MTOR MTOR NPPA NPPA LTBR LTBR IFNGR2 IFNGR2 TEK TEK TCEB1 TCEB1 MKNK1 MKNK1 LOC102748068 LOC102748068 LOC102739299 LOC102739299 IGF1R IGF1R AKT1 AKT1 HIF1A HIF1A LOC102745161 LOC102745161 MAP2K2 MAP2K2 VHL VHL LOC102749673 LOC102749673 AKT3 AKT3 IFNG IFNG LOC102740002 LOC102740002 RPS6KB1 RPS6KB1 LOC102749675 LOC102749675 PDHA1 PDHA1 ANGPT2 ANGPT2 TFRC TFRC EGLN1 EGLN1 IL6 IL6 ENO3 ENO3 MAPK1 MAPK1 MKNK2 MKNK2 LOC102735415 LOC102735415 LOC102730373 LOC102730373 LOC102726827 LOC102726827 TF TF EGLN2 EGLN2 PIK3CD PIK3CD PIK3CA PIK3CA ANGPT4 ANGPT4 LOC102740821 LOC102740821 LDHA LDHA CREBBP CREBBP LOC102737030 LOC102737030 LOC102736516 LOC102736516 LOC102735329 LOC102735329 PDHB PDHB LOC102748129 LOC102748129 LOC102751087 LOC102751087 PFKL PFKL LOC102731850 LOC102731850 LOC102740057 LOC102740057 EIF4E2 EIF4E2 INS INS LOC102733049 LOC102733049 STAT3 STAT3 CAMK2A CAMK2A ARSI ARSI LOC102732970 LOC102732970 CDKN1A CDKN1A RPS6KB2 RPS6KB2 LOC102740880 LOC102740880 LOC102751021 LOC102751021 LOC102730129 LOC102730129 FCGBP FCGBP LDHAL6A LDHAL6A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PGK1Phosphoglycerate kinase. (417 aa)
PGK2Phosphoglycerate kinase. (417 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
ARNTAryl hydrocarbon receptor nuclear translocator isoform X1. (786 aa)
LOC102740749Phosphotransferase; Belongs to the hexokinase family. (82 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (286 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
RBX1E3 ubiquitin-protein ligase RBX1 isoform X3. (108 aa)
EP300Histone acetyltransferase p300. (2425 aa)
IGF1Insulin-like growth factor I isoform X1. (153 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
LOC102751010Nitric oxide synthase, inducible-like. (531 aa)
ANGPT1Angiopoietin-1 isoform X1. (402 aa)
TIMP1Metalloproteinase inhibitor 1. (207 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (254 aa)
LOC10272942740S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
HK3Hexokinase-3. (954 aa)
EIF4E1BEukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. (215 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (574 aa)
SERPINE1Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa)
ZANZonadhesin. (2627 aa)
ENO1Alpha-enolase isoform X2. (434 aa)
PFKFB36-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3. (361 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
NPPANatriuretic peptides A. (150 aa)
LTBRTumor necrosis factor receptor superfamily member 3 isoform X1. (421 aa)
IFNGR2Interferon gamma receptor 2. (115 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
TCEB1Transcription elongation factor B polypeptide 1; Belongs to the SKP1 family. (112 aa)
MKNK1MAP kinase-interacting serine/threonine-protein kinase 1; Belongs to the protein kinase superfamily. (415 aa)
LOC102748068Cytochrome b-245 heavy chain-like. (135 aa)
LOC102739299Fructose-bisphosphate aldolase A-like. (160 aa)
IGF1RInsulin-like growth factor 1 receptor-like. (291 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
LOC102745161Signal transducer and activator of transcription 3-like. (301 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
VHLVon Hippel-Lindau disease tumor suppressor. (219 aa)
LOC102749673Insulin-like growth factor 1 receptor-like. (143 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
LOC102740002Glyceraldehyde-3-phosphate dehydrogenase. (290 aa)
RPS6KB1Non-specific serine/threonine protein kinase. (445 aa)
LOC102749675Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (391 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa)
ANGPT2Angiopoietin-2 isoform X1. (495 aa)
TFRCTransferrin receptor protein 1 isoform X1. (770 aa)
EGLN1Egl nine homolog 1. (128 aa)
IL6Interleukin-6 isoform X1. (212 aa)
ENO3Beta-enolase isoform X1. (434 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
MKNK2MAP kinase-interacting serine/threonine-protein kinase 2 isoform X2; Belongs to the protein kinase superfamily. (463 aa)
LOC102735415Phosphoinositide phospholipase C. (309 aa)
LOC102730373Cytochrome b-245 heavy chain-like. (550 aa)
LOC102726827Eukaryotic translation initiation factor 4E-like; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
TFSerotransferrin; Belongs to the transferrin family. (709 aa)
EGLN2Egl nine homolog 2-like. (405 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
ANGPT4Angiopoietin-4. (498 aa)
LOC102740821Glyceraldehyde-3-phosphate dehydrogenase-like; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (332 aa)
CREBBPCREB-binding protein-like. (1411 aa)
LOC102737030Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. (627 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
LOC102735329Vascular endothelial growth factor receptor 1-like. (351 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
LOC102748129Egl nine homolog 3-like. (239 aa)
LOC102751087Nitric oxide synthase, inducible-like. (430 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (751 aa)
LOC102731850Tyrosine-protein kinase receptor. (757 aa)
LOC102740057Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (186 aa)
EIF4E2Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family. (192 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
LOC1027330496-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3-like isoform X2. (140 aa)
STAT3Signal transducer and activator of transcription 3-like. (424 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (476 aa)
ARSIArylsulfatase I. (575 aa)
LOC102732970Enolase-like protein ENO4-like. (125 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (161 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
LOC102740880Nitric oxide synthase, endothelial-like. (619 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102730129Uncharacterized protein LOC102730129. (471 aa)
FCGBPLOW QUALITY PROTEIN: Fc of IgG binding protein. (2990 aa)
LDHAL6AL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (327 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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