STRINGSTRING
PDIK1L PDIK1L CITED2 CITED2 NBR1 NBR1 LOC102735556 LOC102735556 TBC1D17 TBC1D17 SPEN SPEN LOC102744509 LOC102744509 LOC102740077 LOC102740077 LOC102749849 LOC102749849 LOC102740574 LOC102740574 LOC102739181 LOC102739181 LOC102746862 LOC102746862 LOC102734169 LOC102734169 REM1 REM1 BCL2L1 BCL2L1 KRAS KRAS MRAS MRAS NRAS NRAS CSDE1 CSDE1 LOC102742246 LOC102742246 TFEB TFEB LOC102735345 LOC102735345 LOC102750498 LOC102750498 FOXO3 FOXO3 MAPK10 MAPK10 GEM GEM ATF4 ATF4 USP31 USP31 TTC18 TTC18 LOC102728200 LOC102728200 METTL17 METTL17 RRAD RRAD USP11 USP11 LOC102726691 LOC102726691 GABARAPL1 GABARAPL1 STK35 STK35 LOC102750322 LOC102750322 TAX1BP1 TAX1BP1 SRC SRC FIS1 FIS1 LOC102729636 LOC102729636 RASL11B RASL11B USP32 USP32 LOC102744319 LOC102744319 RIT1 RIT1 FUNDC2 FUNDC2 MAPK8 MAPK8 PINK1 PINK1 TFE3 TFE3 ERAS ERAS LY6G5B LY6G5B CSNK2B CSNK2B HIF1A HIF1A TP53 TP53 GABARAP GABARAP LOC102745784 LOC102745784 ATG5 ATG5 JUN JUN ATG9A ATG9A USP15 USP15 EIF2AK3 EIF2AK3 USP8 USP8 CALCOCO2 CALCOCO2 SP1 SP1 AGFG1 AGFG1 RAB7A RAB7A RRAS RRAS TBC1D15 TBC1D15 HIF3A HIF3A LOC102729273 LOC102729273 PGAM5 PGAM5 LOC102731205 LOC102731205 NPAS1 NPAS1 LOC102745606 LOC102745606 LOC102745512 LOC102745512 UBA52 UBA52 AMBRA1 AMBRA1 LOC102747337 LOC102747337
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDIK1LSerine/threonine-protein kinase PDIK1L. (251 aa)
CITED2Cbp/p300-interacting transactivator 2. (271 aa)
NBR1Next to BRCA1 gene 1 protein. (948 aa)
LOC102735556Mitogen-activated protein kinase 9-like. (134 aa)
TBC1D17TBC1 domain family member 17 isoform X1. (651 aa)
SPENMsx2-interacting protein. (3050 aa)
LOC102744509Autophagy protein 5-like. (78 aa)
LOC102740077Optineurin-like. (123 aa)
LOC102749849Microphthalmia-associated transcription factor-like. (181 aa)
LOC102740574Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (400 aa)
LOC102739181Ubiquitin carboxyl-terminal hydrolase 4-like; Belongs to the peptidase C19 family. (611 aa)
LOC102746862ubiquitin-40S ribosomal protein S27a-like isoform X1. (156 aa)
LOC102734169Gamma-aminobutyric acid receptor-associated protein-like 2-like. (117 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
BCL2L1Bcl-2-like protein 1 isoform X1. (233 aa)
KRASGTPase KRas isoform X2. (188 aa)
MRASRas-related protein M-Ras. (208 aa)
NRASGTPase NRas. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
LOC102742246BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like. (149 aa)
TFEBTranscription factor EB. (329 aa)
LOC102735345Mitochondrial import receptor subunit TOM7 homolog. (55 aa)
LOC102750498Casein kinase II subunit alpha-like isoform X1; Belongs to the protein kinase superfamily. (391 aa)
FOXO3Forkhead box protein O3. (672 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
USP31Ubiquitin carboxyl-terminal hydrolase 31; Belongs to the peptidase C19 family. (1155 aa)
TTC18Tetratricopeptide repeat protein 18. (1124 aa)
LOC102728200ubiquitin-40S ribosomal protein S27a-like. (154 aa)
METTL17Methyltransferase-like protein 17, mitochondrial. (464 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (952 aa)
LOC102726691BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X2. (194 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1 isoform X1. (117 aa)
STK35Serine/threonine-protein kinase 35 isoform X1. (538 aa)
LOC102750322polyubiquitin-B-like. (153 aa)
TAX1BP1Tax1-binding protein 1 homolog isoform X1. (686 aa)
SRCTyrosine-protein kinase. (536 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
LOC102729636polyubiquitin-B-like. (77 aa)
RASL11BRas-like protein family member 11B. (248 aa)
USP32Ubiquitin carboxyl-terminal hydrolase 32; Belongs to the peptidase C19 family. (1042 aa)
LOC102744319FUN14 domain-containing protein 1-like. (155 aa)
RIT1GTP-binding protein Rit1. (219 aa)
FUNDC2FUN14 domain-containing protein 2 isoform X2. (185 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PINK1Serine/threonine-protein kinase PINK1, mitochondrial. (488 aa)
TFE3Transcription factor E3 isoform X1. (571 aa)
ERASGTPase ERas. (233 aa)
LY6G5BLymphocyte antigen 6 complex locus protein G5b. (195 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
LOC102745784Mitochondrial Rho GTPase 1-like. (495 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (255 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (743 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1114 aa)
USP8Ubiquitin carboxyl-terminal hydrolase 8 isoform X1; Belongs to the peptidase C19 family. (1116 aa)
CALCOCO2Calcium-binding and coiled-coil domain-containing protein 2 isoform X2. (449 aa)
SP1Transcription factor Sp1 isoform X1. (786 aa)
AGFG1arf-GAP domain and FG repeat-containing protein 1 isoform X2. (492 aa)
RAB7ARas-related protein Rab-7a isoform X1. (207 aa)
RRASRas-related protein R-Ras. (218 aa)
TBC1D15TBC1 domain family member 15. (860 aa)
HIF3AHypoxia-inducible factor 3-alpha isoform X1. (669 aa)
LOC102729273GTP-binding protein Rit2-like isoform X1. (217 aa)
PGAM5Serine/threonine-protein phosphatase PGAM5, mitochondrial isoform X1. (289 aa)
LOC102731205Ubiquitin carboxyl-terminal hydrolase 43-like; Belongs to the peptidase C19 family. (535 aa)
NPAS1Neuronal PAS domain-containing protein 1 isoform X1. (593 aa)
LOC102745606Ubiquitin carboxyl-terminal hydrolase 43-like. (411 aa)
LOC102745512Ubiquitin carboxyl-terminal hydrolase 32-like; Belongs to the peptidase C19 family. (521 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X3. (128 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1-like. (299 aa)
LOC102747337ubiquitin-40S ribosomal protein S27a-like. (154 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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