STRINGSTRING
LOC102740574 LOC102740574 LOC102751021 LOC102751021 LOC102734169 LOC102734169 LOC102741364 LOC102741364 LOC102737780 LOC102737780 LOC102727190 LOC102727190 LOC102736146 LOC102736146 LOC102744509 LOC102744509 LOC102737775 LOC102737775 LOC102743057 LOC102743057 LOC102735948 LOC102735948 LOC102731352 LOC102731352 PRKACA PRKACA RPS6KB2 RPS6KB2 LOC102735556 LOC102735556 CTSD CTSD AKT1S1 AKT1S1 KCNK1 KCNK1 MTMR4 MTMR4 INS INS LOC102731850 LOC102731850 SMCR8 SMCR8 ATG4A ATG4A LOC102728885 LOC102728885 PDIK1L PDIK1L AMBRA1 AMBRA1 LOC102736516 LOC102736516 NPAS1 NPAS1 PIK3CA PIK3CA PIK3CD PIK3CD DEPTOR DEPTOR LOC102729273 LOC102729273 LOC102740321 LOC102740321 LOC102740618 LOC102740618 TSSK2 TSSK2 HIF3A HIF3A PIK3R4 PIK3R4 TSSK6 TSSK6 RRAS RRAS RAB39A RAB39A MAPK1 MAPK1 UVRAG UVRAG ULK2 ULK2 RRAGC RRAGC RAB7A RAB7A RAB43 RAB43 EIF2AK4 EIF2AK4 ITPR1 ITPR1 WIPI1 WIPI1 RRAGA RRAGA IFITM3 IFITM3 LOC102739213 LOC102739213 ATG4D ATG4D EIF2AK3 EIF2AK3 STX17 STX17 RPS6KB1 RPS6KB1 VMP1 VMP1 RAF1 RAF1 AKT3 AKT3 LOC102749673 LOC102749673 ATG9A ATG9A ATG5 ATG5 LOC102730047 LOC102730047 SH3GLB1 SH3GLB1 GABARAP GABARAP MTMR14 MTMR14 MAP2K2 MAP2K2 LOC102727326 LOC102727326 DAPK3 DAPK3 TSSK4 TSSK4 HIF1A HIF1A ERAS ERAS AKT1 AKT1 IGF1R IGF1R MAPK8 MAPK8 PRKX PRKX HMGB2 HMGB2 CAMKK2 CAMKK2 LOC102739096 LOC102739096 PRKACB PRKACB RAB39B RAB39B ATG12 ATG12 RIT1 RIT1 TRAF6 TRAF6 ATG14 ATG14 TANK TANK ATG2B ATG2B IRS1 IRS1 MTOR MTOR LOC102733761 LOC102733761 DDIT4L DDIT4L RAB19 RAB19 NOL4 NOL4 PRKCQ PRKCQ RB1CC1 RB1CC1 RASL11B RASL11B TSSK3 TSSK3 SUPT20H SUPT20H RRAGD RRAGD RRAGB RRAGB PRKAA1 PRKAA1 KIAA1671 KIAA1671 ATG4C ATG4C PTEN PTEN STK35 STK35 GABARAPL1 GABARAPL1 LOC102726691 LOC102726691 RRAD RRAD PPP2CB PPP2CB TTC14 TTC14 DDIT4 DDIT4 LOC102739066 LOC102739066 ERN2 ERN2 LOC102726169 LOC102726169 RASEF RASEF DUS2 DUS2 PIK3C3 PIK3C3 GEM GEM MAP2K1 MAP2K1 TP53INP1 TP53INP1 MAPK10 MAPK10 CTSB CTSB RHEBL1 RHEBL1 PIK3R3 PIK3R3 CSDE1 CSDE1 NRAS NRAS LOC102726446 LOC102726446 MRAS MRAS KRAS KRAS LOC102743442 LOC102743442 BCL2L1 BCL2L1 REM1 REM1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LOC102740574Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (400 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102734169Gamma-aminobutyric acid receptor-associated protein-like 2-like. (117 aa)
LOC102741364Nuclear receptor-binding factor 2-like. (236 aa)
LOC102737780Uncharacterized protein KIAA0226-like. (230 aa)
LOC102727190Serine/threonine-protein kinase STK11-like. (545 aa)
LOC1027361463-phosphoinositide-dependent protein kinase 1-like. (216 aa)
LOC102744509Autophagy protein 5-like. (78 aa)
LOC102737775Uncharacterized protein C20orf112 homolog. (438 aa)
LOC102743057Autophagy-related protein 101. (218 aa)
LOC102735948Autophagy-related protein 13-like. (287 aa)
LOC102731352Serine/threonine-protein kinase/endoribonuclease IRE1-like. (414 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
LOC102735556Mitogen-activated protein kinase 9-like. (134 aa)
CTSDCathepsin D; Belongs to the peptidase A1 family. (410 aa)
AKT1S1Proline-rich AKT1 substrate 1. (276 aa)
KCNK1Potassium channel subfamily K member. (336 aa)
MTMR4Myotubularin-related protein 4-like. (585 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
LOC102731850Tyrosine-protein kinase receptor. (757 aa)
SMCR8smith-Magenis syndrome chromosomal region candidate gene 8 protein. (937 aa)
ATG4ACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (398 aa)
LOC102728885High mobility group protein B3-like isoform X1. (201 aa)
PDIK1LSerine/threonine-protein kinase PDIK1L. (251 aa)
AMBRA1Activating molecule in BECN1-regulated autophagy protein 1-like. (299 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
NPAS1Neuronal PAS domain-containing protein 1 isoform X1. (593 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
DEPTORDEP domain-containing mTOR-interacting protein. (305 aa)
LOC102729273GTP-binding protein Rit2-like isoform X1. (217 aa)
LOC102740321High mobility group protein B4-like. (194 aa)
LOC102740618Testis-specific serine/threonine-protein kinase 1-like; Belongs to the protein kinase superfamily. (367 aa)
TSSK2Testis-specific serine/threonine-protein kinase 2; Belongs to the protein kinase superfamily. (361 aa)
HIF3AHypoxia-inducible factor 3-alpha isoform X1. (669 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
TSSK6Testis-specific serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (273 aa)
RRASRas-related protein R-Ras. (218 aa)
RAB39ARas-related protein Rab-39A. (217 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
UVRAGUV radiation resistance-associated gene protein. (697 aa)
ULK2Serine/threonine-protein kinase ULK2. (1036 aa)
RRAGCRas-related GTP-binding protein C isoform X1. (399 aa)
RAB7ARas-related protein Rab-7a isoform X1. (207 aa)
RAB43Ras-related protein Rab-43. (212 aa)
EIF2AK4Eukaryotic translation initiation factor 2-alpha kinase 4. (1653 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (1244 aa)
WIPI1WD repeat domain phosphoinositide-interacting protein 1 isoform X1. (446 aa)
RRAGARas-related GTP-binding protein A. (313 aa)
IFITM3Interferon-induced transmembrane protein 3. (146 aa)
LOC102739213High mobility group protein B1-like. (214 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (330 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1114 aa)
STX17Syntaxin-17; Belongs to the syntaxin family. (302 aa)
RPS6KB1Non-specific serine/threonine protein kinase. (445 aa)
VMP1Vacuole membrane protein 1. (377 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
LOC102749673Insulin-like growth factor 1 receptor-like. (143 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (743 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (255 aa)
LOC102730047Tuberin-like. (353 aa)
SH3GLB1endophilin-B1 isoform X1. (393 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
MTMR14Myotubularin-related protein 14. (477 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC102727326Cathepsin L1-like isoform X1; Belongs to the peptidase C1 family. (334 aa)
DAPK3Death-associated protein kinase 3; Belongs to the protein kinase superfamily. (454 aa)
TSSK4Testis-specific serine/threonine-protein kinase 4 isoform X1. (339 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
ERASGTPase ERas. (233 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
IGF1RInsulin-like growth factor 1 receptor-like. (291 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
PRKXcAMP-dependent protein kinase catalytic subunit PRKX; Belongs to the protein kinase superfamily. (361 aa)
HMGB2High mobility group protein B2 isoform X1. (210 aa)
CAMKK2Calcium/calmodulin-dependent protein kinase kinase 2 isoform X1. (578 aa)
LOC102739096Protein C9orf72 homolog. (235 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
RAB39BRas-related protein Rab-39B. (213 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
RIT1GTP-binding protein Rit1. (219 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (492 aa)
TANKTRAF family member-associated NF-kappa-B activator isoform X2. (426 aa)
ATG2BAutophagy-related protein 2 homolog B. (1878 aa)
IRS1Insulin receptor substrate 1-like isoform X1. (1236 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
LOC102733761Ras-related protein Rab-33A-like. (136 aa)
DDIT4LDNA damage-inducible transcript 4-like protein. (193 aa)
RAB19Ras-related protein Rab-19 isoform X1. (217 aa)
NOL4Nucleolar protein 4. (548 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform X1. (1593 aa)
RASL11BRas-like protein family member 11B. (248 aa)
TSSK3Testis-specific serine/threonine-protein kinase 3 isoform X1. (268 aa)
SUPT20HTranscription factor SPT20 homolog isoform X1. (811 aa)
RRAGDRas-related GTP-binding protein D. (396 aa)
RRAGBRas-related GTP-binding protein B isoform X1. (374 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
KIAA1671Uncharacterized protein KIAA1671 homolog. (308 aa)
ATG4CCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (460 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
STK35Serine/threonine-protein kinase 35 isoform X1. (538 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1 isoform X1. (117 aa)
LOC102726691BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X2. (194 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
TTC14Tetratricopeptide repeat protein 14. (769 aa)
DDIT4DNA damage-inducible transcript 4 protein. (231 aa)
LOC102739066GTP-binding protein Rheb-like. (142 aa)
ERN2Serine/threonine-protein kinase/endoribonuclease IRE2. (926 aa)
LOC102726169Transcription factor SPT20 homolog. (808 aa)
RASEFRas and EF-hand domain-containing protein. (742 aa)
DUS2tRNA-dihydrouridine(20) synthase [NAD(P)+]-like isoform X1. (493 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (811 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
TP53INP1Tumor protein p53-inducible nuclear protein 1 isoform X1. (239 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (339 aa)
RHEBL1GTPase RhebL1. (183 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
NRASGTPase NRas. (189 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
MRASRas-related protein M-Ras. (208 aa)
KRASGTPase KRas isoform X2. (188 aa)
LOC102743442Autophagy-related protein 3. (314 aa)
BCL2L1Bcl-2-like protein 1 isoform X1. (233 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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