STRINGSTRING
ATP6V1B2 ATP6V1B2 SOS1 SOS1 LOC102740618 LOC102740618 TSSK2 TSSK2 LOC102726827 LOC102726827 LOC102737920 LOC102737920 PRR5 PRR5 LOC102731813 LOC102731813 ATP6V1C1 ATP6V1C1 FLCN FLCN TSSK6 TSSK6 WNT4 WNT4 MAPKAP1 MAPKAP1 TBCA TBCA FZD9 FZD9 IKBKB IKBKB WNT3 WNT3 WNT9B WNT9B MAPK1 MAPK1 WNT3A WNT3A LOC102732238 LOC102732238 WNT2B WNT2B TTI1 TTI1 LOC102731850 LOC102731850 EIF4E2 EIF4E2 INS INS NPRL2 NPRL2 WNT8B WNT8B AKT1S1 AKT1S1 WDR24 WDR24 RPS6KB2 RPS6KB2 LOC102734846 LOC102734846 LOC102730118 LOC102730118 LOC102736146 LOC102736146 LOC102726484 LOC102726484 LOC102727190 LOC102727190 LOC102740078 LOC102740078 LOC102727084 LOC102727084 WNT10B WNT10B LOC102751021 LOC102751021 WNT11 WNT11 LOC102748485 LOC102748485 LOC102745799 LOC102745799 WNT6 WNT6 WNT10A WNT10A RICTOR RICTOR ULK2 ULK2 RRAGC RRAGC LOC102735500 LOC102735500 CLIP1 CLIP1 WNT5B WNT5B DVL1 DVL1 GSK3B GSK3B LOC102734199 LOC102734199 TELO2 TELO2 RRAGA RRAGA RPS6 RPS6 RPS6KA3 RPS6KA3 CHUK CHUK WNT5A WNT5A LOC102749586 LOC102749586 RPS6KB1 RPS6KB1 RAF1 RAF1 FZD10 FZD10 AKT3 AKT3 LOC102750211 LOC102750211 EIF4E3 EIF4E3 SESN2 SESN2 LIM2 LIM2 LOC102749673 LOC102749673 GATSL3 GATSL3 LOC102730047 LOC102730047 ATP6V1A ATP6V1A DVL2 DVL2 MAP2K2 MAP2K2 TSSK4 TSSK4 TNF TNF ERAS ERAS AKT1 AKT1 IGF1R IGF1R DVL3 DVL3 TNFRSF1A TNFRSF1A STRADA STRADA WNT8A WNT8A CAB39L CAB39L LAMTOR2 LAMTOR2 MIOS MIOS FAM76B FAM76B GRB10 GRB10 FZD2 FZD2 IRS1 IRS1 MTOR MTOR LAMTOR3 LAMTOR3 DDIT4L DDIT4L FZD3 FZD3 ATP6V1D ATP6V1D FZD7 FZD7 LOC102732272 LOC102732272 RASL11B RASL11B TSSK3 TSSK3 LAMTOR4 LAMTOR4 RPS6KA6 RPS6KA6 REM1 REM1 KRAS KRAS LPIN2 LPIN2 LOC102726446 LOC102726446 WNT16 WNT16 ATP6V1B1 ATP6V1B1 RASGEF1A RASGEF1A NRAS NRAS CSDE1 CSDE1 PIK3R3 PIK3R3 WNT1 WNT1 RHEBL1 RHEBL1 ATP6V1G3 ATP6V1G3 MAP2K1 MAP2K1 GEM GEM LOC102727975 LOC102727975 LOC102739066 LOC102739066 DDIT4 DDIT4 IGF1 IGF1 GRAP GRAP RRAD RRAD STK35 STK35 RRAGD RRAGD RRAGB RRAGB LOC102743180 LOC102743180 FZD5 FZD5 PRKAA1 PRKAA1 KIAA1671 KIAA1671 TBC1D7 TBC1D7 EIF4E1B EIF4E1B LRP6 LRP6 LOC102729427 LOC102729427 LAMTOR5 LAMTOR5 PTEN PTEN LOC102739552 LOC102739552 PDIK1L PDIK1L LOC102735530 LOC102735530 STRADB STRADB LOC102736317 LOC102736317 DEPDC5 DEPDC5 LOC102730084 LOC102730084 LOC102736516 LOC102736516 SGK1 SGK1 FZD4 FZD4 GRB7 GRB7 LOC102732719 LOC102732719 LOC102727255 LOC102727255 PIK3CA PIK3CA LOC102726140 LOC102726140 ATP6V1H ATP6V1H PIK3CD PIK3CD DEPTOR DEPTOR
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
SOS1Son of sevenless homolog 1-like. (281 aa)
LOC102740618Testis-specific serine/threonine-protein kinase 1-like; Belongs to the protein kinase superfamily. (367 aa)
TSSK2Testis-specific serine/threonine-protein kinase 2; Belongs to the protein kinase superfamily. (361 aa)
LOC102726827Eukaryotic translation initiation factor 4E-like; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
LOC102737920GRB2-related adapter protein-like. (100 aa)
PRR5Proline-rich protein 5. (293 aa)
LOC102731813Frizzled-6-like; Belongs to the G-protein coupled receptor Fz/Smo family. (400 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
FLCNFolliculin. (579 aa)
TSSK6Testis-specific serine/threonine-protein kinase 6; Belongs to the protein kinase superfamily. (273 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
MAPKAP1Target of rapamycin complex 2 subunit MAPKAP1. (122 aa)
TBCATubulin-specific chaperone A; Belongs to the TBCA family. (103 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (407 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (218 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
LOC102732238Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (265 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
TTI1TELO2-interacting protein 1 homolog. (1092 aa)
LOC102731850Tyrosine-protein kinase receptor. (757 aa)
EIF4E2Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family. (192 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
NPRL2Nitrogen permease regulator 2-like protein. (380 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (322 aa)
AKT1S1Proline-rich AKT1 substrate 1. (276 aa)
WDR24WD repeat-containing protein 24. (790 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
LOC102734846V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
LOC102730118V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
LOC1027361463-phosphoinositide-dependent protein kinase 1-like. (216 aa)
LOC102726484Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (207 aa)
LOC102727190Serine/threonine-protein kinase STK11-like. (545 aa)
LOC102740078Ragulator complex protein LAMTOR1-like. (98 aa)
LOC102727084Microtubule-associated tumor suppressor candidate 2-like. (199 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
LOC102748485WD repeat-containing protein 59-like. (135 aa)
LOC102745799Protein FAM76A-like. (171 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (261 aa)
RICTORRapamycin-insensitive companion of mTOR isoform X1. (1732 aa)
ULK2Serine/threonine-protein kinase ULK2. (1036 aa)
RRAGCRas-related GTP-binding protein C isoform X1. (399 aa)
LOC102735500Cyclic nucleotide-binding domain-containing protein 2-like. (147 aa)
CLIP1CAP-Gly domain-containing linker protein 1 isoform X1. (1438 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (693 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
LOC102734199V-type proton ATPase subunit E 1-like. (206 aa)
TELO2Telomere length regulation protein TEL2 homolog. (822 aa)
RRAGARas-related GTP-binding protein A. (313 aa)
RPS640S ribosomal protein S6. (80 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
LOC102749586V-type proton ATPase subunit E 2-like. (226 aa)
RPS6KB1Non-specific serine/threonine protein kinase. (445 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
LOC102750211Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (154 aa)
EIF4E3Eukaryotic translation initiation factor 4E type 3; Belongs to the eukaryotic initiation factor 4E family. (118 aa)
SESN2Sestrin-2. (481 aa)
LIM2Lens fiber membrane intrinsic protein; Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis; Belongs to the PMP-22/EMP/MP20 family. (173 aa)
LOC102749673Insulin-like growth factor 1 receptor-like. (143 aa)
GATSL3GATS-like protein 3. (329 aa)
LOC102730047Tuberin-like. (353 aa)
ATP6V1AV-type proton ATPase catalytic subunit A. (394 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (734 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
TSSK4Testis-specific serine/threonine-protein kinase 4 isoform X1. (339 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
ERASGTPase ERas. (233 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
IGF1RInsulin-like growth factor 1 receptor-like. (291 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (358 aa)
STRADASTE20-related kinase adapter protein alpha isoform X1. (431 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
CAB39LCalcium-binding protein 39-like isoform X2. (337 aa)
LAMTOR2Ragulator complex protein LAMTOR2 isoform X1. (125 aa)
MIOSWD repeat-containing protein mio. (875 aa)
FAM76BProtein FAM76B. (339 aa)
GRB10Growth factor receptor-bound protein 10. (586 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
IRS1Insulin receptor substrate 1-like isoform X1. (1236 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
LAMTOR3Ragulator complex protein LAMTOR3. (111 aa)
DDIT4LDNA damage-inducible transcript 4-like protein. (193 aa)
FZD3Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
ATP6V1DV-type proton ATPase subunit D. (257 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
LOC102732272Ragulator complex protein LAMTOR1-like. (152 aa)
RASL11BRas-like protein family member 11B. (248 aa)
TSSK3Testis-specific serine/threonine-protein kinase 3 isoform X1. (268 aa)
LAMTOR4Ragulator complex protein LAMTOR4. (99 aa)
RPS6KA6Ribosomal protein S6 kinase. (744 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
KRASGTPase KRas isoform X2. (188 aa)
LPIN2Phosphatidate phosphatase LPIN2. (937 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (149 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
RASGEF1Aras-GEF domain-containing family member 1A. (480 aa)
NRASGTPase NRas. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
RHEBL1GTPase RhebL1. (183 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (295 aa)
LOC102727975V-type proton ATPase subunit E 1-like isoform X1. (226 aa)
LOC102739066GTP-binding protein Rheb-like. (142 aa)
DDIT4DNA damage-inducible transcript 4 protein. (231 aa)
IGF1Insulin-like growth factor I isoform X1. (153 aa)
GRAPGRB2-related adapter protein. (210 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
STK35Serine/threonine-protein kinase 35 isoform X1. (538 aa)
RRAGDRas-related GTP-binding protein D. (396 aa)
RRAGBRas-related GTP-binding protein B isoform X1. (374 aa)
LOC102743180DEP domain-containing protein 5-like. (1079 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
KIAA1671Uncharacterized protein KIAA1671 homolog. (308 aa)
TBC1D7TBC1 domain family member 7 isoform X1. (293 aa)
EIF4E1BEukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. (215 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
LOC10272942740S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
LAMTOR5Ragulator complex protein LAMTOR5. (91 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
LOC102739552Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
PDIK1LSerine/threonine-protein kinase PDIK1L. (251 aa)
LOC102735530ras-GEF domain-containing family member 1B-like. (472 aa)
STRADBSTE20-related kinase adapter protein beta. (415 aa)
LOC102736317DEP domain-containing protein 5-like. (134 aa)
DEPDC5DEP domain-containing protein 5-like. (370 aa)
LOC102730084Growth factor receptor-bound protein 14-like. (226 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
GRB7Growth factor receptor-bound protein 7. (403 aa)
LOC102732719Ribosomal protein S6 kinase alpha-1-like. (200 aa)
LOC102727255Nucleoporin SEH1-like; Belongs to the WD repeat SEC13 family. (468 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC102726140Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family. (647 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (470 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
DEPTORDEP domain-containing mTOR-interacting protein. (305 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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