STRINGSTRING
FGF16 FGF16 LPAR4 LPAR4 IBSP IBSP SPP1 SPP1 HGF HGF PDGFC PDGFC FGF20 FGF20 IL7 IL7 BCL2L1 BCL2L1 KRAS KRAS FGF9 FGF9 PPP2R3A PPP2R3A LOC102726446 LOC102726446 TGFA TGFA MCL1 MCL1 NRAS NRAS CSDE1 CSDE1 ITGA5 ITGA5 ITGA7 ITGA7 CDK2 CDK2 ERBB3 ERBB3 PIK3R3 PIK3R3 LAMC1 LAMC1 CCND3 CCND3 RHEBL1 RHEBL1 COL2A1 COL2A1 LOC102742552 LOC102742552 COL9A1 COL9A1 FOXO3 FOXO3 FGF10 FGF10 MAP2K1 MAP2K1 CCNE2 CCNE2 EREG EREG ATF4 ATF4 EPGN EPGN LOC102741253 LOC102741253 ITGA10 ITGA10 LOC102727373 LOC102727373 GNG3 GNG3 CHRM1 CHRM1 LOC102728392 LOC102728392 COL1A2 COL1A2 LOC102739066 LOC102739066 FGF8 FGF8 DDIT4 DDIT4 IGF1 IGF1 PPP2CB PPP2CB ANGPT1 ANGPT1 VTN VTN NFKB1 NFKB1 COL4A1 COL4A1 LOC102737670 LOC102737670 PTEN PTEN LOC102729427 LOC102729427 GNGT1 GNGT1 GNG11 GNG11 LOC102747757 LOC102747757 LOC102747471 LOC102747471 IFNB1 IFNB1 CDKN1B CDKN1B FGFR4 FGFR4 EIF4E1B EIF4E1B GNB5 GNB5 PRKAA1 PRKAA1 CREB1 CREB1 LPAR1 LPAR1 GNG10 GNG10 GNB2 GNB2 ZAN ZAN CD19 CD19 ITGB3 ITGB3 SGK3 SGK3 SGK2 SGK2 LOC102731565 LOC102731565 IL4 IL4 THBS3 THBS3 EFNA1 EFNA1 ADAM15 ADAM15 LOC102745146 LOC102745146 FN1 FN1 YWHAB YWHAB F2R F2R MTOR MTOR PRLR PRLR FGF7 FGF7 GALK2 GALK2 IRS1 IRS1 NTF3 NTF3 VWF VWF CSF3R CSF3R FGFR3 FGFR3 PPP2R5D PPP2R5D LOC102728321 LOC102728321 PPP2R2A PPP2R2A GNG5 GNG5 MTCP1 MTCP1 TEK TEK JAK2 JAK2 FGF5 FGF5 COL9A2 COL9A2 FASLG FASLG ITGB1 ITGB1 LOC102740189 LOC102740189 GNB3 GNB3 COL9A3 COL9A3 PKN1 PKN1 IL2 IL2 MYB MYB IGF1R IGF1R AKT1 AKT1 ERAS ERAS ATF6B ATF6B PKN2 PKN2 G6PC G6PC PCK2 PCK2 CREB3L3 CREB3L3 LOC102749767 LOC102749767 MAP2K2 MAP2K2 FGFR2 FGFR2 TP53 TP53 KITLG KITLG GNG13 GNG13 CCNE1 CCNE1 NGF NGF LOC102730047 LOC102730047 NTRK2 NTRK2 LOC102741496 LOC102741496 IKBKG IKBKG LOC102749673 LOC102749673 VEGFC VEGFC LOC102745475 LOC102745475 AKT3 AKT3 CDK4 CDK4 PPP2R5C PPP2R5C MDM2 MDM2 LOC102743308 LOC102743308 HSP90B1 HSP90B1 RAF1 RAF1 RPS6KB1 RPS6KB1 LOC102744445 LOC102744445 LPAR6 LPAR6 LOC102742903 LOC102742903 CHAD CHAD LOC102743414 LOC102743414 ITGA4 ITGA4 LOC102739404 LOC102739404 ITGA9 ITGA9 CHUK CHUK ANGPT2 ANGPT2 GNGT2 GNGT2 ITGB7 ITGB7 CSF1R CSF1R MFF MFF COL4A4 COL4A4 THBS1 THBS1 LOC102734089 LOC102734089 ATF2 ATF2 GSK3B GSK3B LOC102729555 LOC102729555 IL2RB IL2RB IL6 IL6 LOC102747503 LOC102747503 LOC102746004 LOC102746004 PPP2R2C PPP2R2C VWA2 VWA2 CRTC2 CRTC2 MAPK1 MAPK1 IKBKB IKBKB LOC102750756 LOC102750756 PPP2R5A PPP2R5A EPOR EPOR LOC102747801 LOC102747801 LPAR2 LPAR2 CCND1 CCND1 FGF17 FGF17 LOC102741220 LOC102741220 LOC102726827 LOC102726827 GNG8 GNG8 PPP2R5E PPP2R5E LOC102737823 LOC102737823 FGF3 FGF3 CHRM2 CHRM2 FGF4 FGF4 FGF18 FGF18 PIK3CD PIK3CD LOC102725545 LOC102725545 CSF1 CSF1 IL3RA IL3RA PGF PGF LOC102733219 LOC102733219 LOC102736718 LOC102736718 COL6A2 COL6A2 LOC102742022 LOC102742022 PIK3CA PIK3CA COL6A1 COL6A1 ANGPT4 ANGPT4 GNG4 GNG4 FLT3 FLT3 VEGFB VEGFB GNG2 GNG2 PDGFB PDGFB LOC102737030 LOC102737030 SGK1 SGK1 LOC102736516 LOC102736516 LOC102735329 LOC102735329 LOC102732031 LOC102732031 PDGFRA PDGFRA GYS1 GYS1 FGF21 FGF21 LOC102728378 LOC102728378 YWHAH YWHAH CREB3L1 CREB3L1 HSP90AB1 HSP90AB1 RXRA RXRA COMP COMP NTRK1 NTRK1 LOC102726367 LOC102726367 CASP9 CASP9 PPP2R3B PPP2R3B LOC102750303 LOC102750303 IL4R IL4R LOC102732653 LOC102732653 IFNAR1 IFNAR1 FLT3LG FLT3LG LOC102729200 LOC102729200 LOC102729499 LOC102729499 JAK3 JAK3 PKN3 PKN3 CSF3 CSF3 G6PC2 G6PC2 LOC102731850 LOC102731850 LOC102740057 LOC102740057 EIF4E2 EIF4E2 FGF6 FGF6 FGF23 FGF23 LOC102745316 LOC102745316 TCL1B TCL1B LAMB2 LAMB2 GNB4 GNB4 LOC102740654 LOC102740654 FGF2 FGF2 INS INS LAMA5 LAMA5 LOC102736544 LOC102736544 IGF2 IGF2 LOC102739775 LOC102739775 NTF4 NTF4 LOC102748147 LOC102748147 LOC102730629 LOC102730629 LOC102744498 LOC102744498 IL3 IL3 FGF22 FGF22 LOC102744822 LOC102744822 CDKN1A CDKN1A RPS6KB2 RPS6KB2 LOC102736146 LOC102736146 LOC102738667 LOC102738667 PCK1 PCK1 LOC102733359 LOC102733359 LOC102749847 LOC102749847 LOC102727190 LOC102727190 LOC102742177 LOC102742177 LOC102740880 LOC102740880 LOC102751021 LOC102751021 LOC102747171 LOC102747171 LOC102730129 LOC102730129 FCGBP FCGBP IFNA14 IFNA14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LPAR4Lysophosphatidic acid receptor 4; Belongs to the G-protein coupled receptor 1 family. (370 aa)
IBSPBone sialoprotein 2. (318 aa)
SPP1Osteopontin isoform X1. (299 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
PDGFCPlatelet-derived growth factor C-like; Belongs to the PDGF/VEGF growth factor family. (345 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (158 aa)
BCL2L1Bcl-2-like protein 1 isoform X1. (233 aa)
KRASGTPase KRas isoform X2. (188 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1. (1153 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
TGFAProtransforming growth factor alpha. (160 aa)
MCL1Induced myeloid leukemia cell differentiation protein Mcl-1 homolog isoform X1. (350 aa)
NRASGTPase NRas. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1054 aa)
ITGA7Integrin alpha-7; Belongs to the integrin alpha chain family. (1181 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1339 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
LAMC1Laminin subunit gamma-1. (1608 aa)
CCND3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (291 aa)
RHEBL1GTPase RhebL1. (183 aa)
COL2A1Collagen alpha-1(II) chain isoform X1. (1487 aa)
LOC102742552Platelet-derived growth factor D-like isoform X1. (370 aa)
COL9A1Collagen alpha-1(IX) chain. (885 aa)
FOXO3Forkhead box protein O3. (672 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (218 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
CCNE2G1/S-specific cyclin-E2; Belongs to the cyclin family. (344 aa)
EREGProepiregulin. (292 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
EPGNEpigen isoform X1. (153 aa)
LOC102741253Amphiregulin-like. (253 aa)
ITGA10LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family. (1165 aa)
LOC102727373Integrin alpha-10-like. (374 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
LOC102728392ephrin-A5-like; Belongs to the ephrin family. (191 aa)
COL1A2Collagen alpha-2(I) chain. (1365 aa)
LOC102739066GTP-binding protein Rheb-like. (142 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (140 aa)
DDIT4DNA damage-inducible transcript 4 protein. (231 aa)
IGF1Insulin-like growth factor I isoform X1. (153 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
ANGPT1Angiopoietin-1 isoform X1. (402 aa)
VTNVitronectin. (456 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (254 aa)
COL4A1Collagen alpha-1(IV) chain. (321 aa)
LOC102737670Cyclin-dependent kinase 6-like. (322 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
LOC10272942740S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC102747757Interferon alpha-1/2-like. (187 aa)
LOC102747471Interferon alpha-1/2-like. (187 aa)
IFNB1Interferon beta. (182 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
FGFR4Fibroblast growth factor receptor. (800 aa)
EIF4E1BEukaryotic translation initiation factor 4E type 1B; Belongs to the eukaryotic initiation factor 4E family. (215 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (345 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
LPAR1Lysophosphatidic acid receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1. (340 aa)
ZANZonadhesin. (2627 aa)
CD19B-lymphocyte antigen CD19. (559 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (852 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (490 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)
LOC102731565Laminin subunit gamma-3-like. (231 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (131 aa)
THBS3Thrombospondin-3 isoform X1. (956 aa)
EFNA1ephrin-A1 isoform X1; Belongs to the ephrin family. (205 aa)
ADAM15Disintegrin and metalloproteinase domain-containing protein 15 isoform X1. (867 aa)
LOC102745146Tumor necrosis factor ligand superfamily member 6-like; Belongs to the tumor necrosis factor family. (173 aa)
FN1Fibronectin isoform X1. (2476 aa)
YWHAB14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (244 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (624 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
GALK2N-acetylgalactosamine kinase. (332 aa)
IRS1Insulin receptor substrate 1-like isoform X1. (1236 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (257 aa)
VWFVon Willebrand factor. (2285 aa)
CSF3RGranulocyte colony-stimulating factor receptor. (430 aa)
FGFR3Fibroblast growth factor receptor. (809 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (676 aa)
LOC102728321High affinity nerve growth factor receptor-like. (109 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
MTCP1Protein p13 MTCP-1. (107 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
JAK2Tyrosine-protein kinase. (952 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (275 aa)
COL9A2Collagen alpha-2(IX) chain. (595 aa)
FASLGTumor necrosis factor ligand superfamily member 6. (130 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
LOC102740189Somatotropin-like. (216 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
COL9A3Collagen alpha-3(IX) chain. (681 aa)
PKN1Serine/threonine-protein kinase N1. (796 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
MYBTranscriptional activator Myb isoform X1. (761 aa)
IGF1RInsulin-like growth factor 1 receptor-like. (291 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
ERASGTPase ERas. (233 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta. (623 aa)
PKN2Serine/threonine-protein kinase N2 isoform X1. (984 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial isoform X2. (640 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (466 aa)
LOC102749767Integrin alpha-IIb-like. (534 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
FGFR2Fibroblast growth factor receptor 2. (658 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
LOC102730047Tuberin-like. (353 aa)
NTRK2BDNF/NT-3 growth factors receptor-like. (420 aa)
LOC102741496BDNF/NT-3 growth factors receptor-like. (97 aa)
IKBKGNF-kappa-B essential modulator isoform X2. (419 aa)
LOC102749673Insulin-like growth factor 1 receptor-like. (143 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (419 aa)
LOC102745475Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like isoform X1. (340 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
LOC102743308Prolactin-like. (229 aa)
HSP90B1Endoplasmin isoform X1. (803 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
RPS6KB1Non-specific serine/threonine protein kinase. (445 aa)
LOC102744445Integrin beta; Belongs to the integrin beta chain family. (197 aa)
LPAR6Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family. (344 aa)
LOC102742903Collagen alpha-1(I) chain-like. (1116 aa)
CHADChondroadherin isoform X1. (359 aa)
LOC102743414Thrombospondin-2-like. (463 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
LOC102739404Integrin alpha-9-like. (152 aa)
ITGA9Integrin alpha-9-like. (470 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
ANGPT2Angiopoietin-2 isoform X1. (495 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (763 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
MFFMitochondrial fission factor isoform X2. (342 aa)
COL4A4Collagen alpha-4(IV) chain-like. (1589 aa)
THBS1Thrombospondin-1 isoform X1. (1170 aa)
LOC102734089Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1-like. (154 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
LOC102729555oncostatin-M-like. (214 aa)
IL2RBInterleukin-2 receptor subunit beta. (552 aa)
IL6Interleukin-6 isoform X1. (212 aa)
LOC102747503Collagen alpha-6(VI) chain-like. (1244 aa)
LOC102746004Bcl-2-like protein 11-like isoform X2. (140 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform. (231 aa)
VWA2Von Willebrand factor A domain-containing protein 2. (804 aa)
CRTC2CREB-regulated transcription coactivator 2. (695 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
LOC10275075614-3-3 protein epsilon-like; Belongs to the 14-3-3 family. (233 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (509 aa)
LOC102747801Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (214 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC102741220Integrin alpha-9-like. (114 aa)
LOC102726827Eukaryotic translation initiation factor 4E-like; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
LOC102737823Fibroblast growth factor 19-like; Belongs to the heparin-binding growth factors family. (115 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (172 aa)
FGF18Fibroblast growth factor 18. (116 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
LOC102725545Caspase-9-like; Belongs to the peptidase C14A family. (275 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (547 aa)
IL3RAInterleukin-3 receptor subunit alpha. (376 aa)
PGFPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
LOC102733219Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (147 aa)
LOC102736718Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
COL6A2Collagen alpha-2(VI) chain. (1021 aa)
LOC10274202214-3-3 protein zeta/delta-like isoform X1; Belongs to the 14-3-3 family. (245 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
COL6A1Collagen alpha-1(VI) chain. (1027 aa)
ANGPT4Angiopoietin-4. (498 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (984 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
LOC102737030Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. (627 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (495 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
LOC102735329Vascular endothelial growth factor receptor 1-like. (351 aa)
LOC102732031Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like. (407 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1090 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
LOC102728378Granulocyte colony-stimulating factor receptor-like. (493 aa)
YWHAH14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (474 aa)
HSP90AB1Heat shock protein HSP 90-beta. (464 aa)
RXRARetinoic acid receptor RXR-alpha. (439 aa)
COMPCartilage oligomeric matrix protein. (728 aa)
NTRK1Tyrosine-protein kinase receptor. (592 aa)
LOC102726367Heat shock protein HSP 90-alpha-like. (262 aa)
CASP9Caspase-9. (171 aa)
PPP2R3BSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (596 aa)
LOC102750303Collagen alpha-1(I) chain-like. (395 aa)
IL4RInterleukin-4 receptor subunit alpha isoform X1. (797 aa)
LOC102732653Nuclear receptor subfamily 4 group A member 1-like. (306 aa)
IFNAR1Interferon alpha/beta receptor 1. (560 aa)
FLT3LGFms-related tyrosine kinase 3 ligand. (290 aa)
LOC102729200Collagen alpha-1(IV) chain-like. (863 aa)
LOC102729499Collagen alpha-1(IV) chain-like. (112 aa)
JAK3Tyrosine-protein kinase. (1139 aa)
PKN3Serine/threonine-protein kinase N3. (889 aa)
CSF3Granulocyte colony-stimulating factor. (195 aa)
G6PC2Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (356 aa)
LOC102731850Tyrosine-protein kinase receptor. (757 aa)
LOC102740057Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (186 aa)
EIF4E2Eukaryotic translation initiation factor 4E type 2; Belongs to the eukaryotic initiation factor 4E family. (192 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (182 aa)
FGF23Fibroblast growth factor 23. (177 aa)
LOC102745316Von Willebrand factor-like. (532 aa)
TCL1BT-cell leukemia/lymphoma protein 1B. (127 aa)
LAMB2Laminin subunit beta-2 isoform X1. (1801 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
LOC102740654Phosphoinositide 3-kinase regulatory subunit 5-like. (111 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
LAMA5Laminin subunit alpha-5-like. (1341 aa)
LOC102736544Thrombospondin-4-like. (685 aa)
IGF2Insulin-like growth factor II. (138 aa)
LOC102739775Breast cancer type 1 susceptibility protein homolog. (471 aa)
NTF4Neurotrophin-4; Belongs to the NGF-beta family. (211 aa)
LOC102748147Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC102730629Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (288 aa)
LOC10274449814-3-3 protein theta-like; Belongs to the 14-3-3 family. (98 aa)
IL3Interleukin-3. (143 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
LOC102744822Fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins [...] (56 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (161 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
LOC1027361463-phosphoinositide-dependent protein kinase 1-like. (216 aa)
LOC102738667Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1-like. (380 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP] isoform X2. (622 aa)
LOC102733359ephrin-A4-like; Belongs to the ephrin family. (166 aa)
LOC102749847Tyrosine-protein kinase JAK1-like. (444 aa)
LOC102727190Serine/threonine-protein kinase STK11-like. (545 aa)
LOC102742177Mast/stem cell growth factor receptor Kit-like. (217 aa)
LOC102740880Nitric oxide synthase, endothelial-like. (619 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102747171Hsp90 co-chaperone Cdc37-like. (341 aa)
LOC102730129Uncharacterized protein LOC102730129. (471 aa)
FCGBPLOW QUALITY PROTEIN: Fc of IgG binding protein. (2990 aa)
IFNA14LOW QUALITY PROTEIN: interferon, alpha 14. (182 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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