STRINGSTRING
MTOR MTOR IRS1 IRS1 PRKACB PRKACB TIMM8A TIMM8A IGF1R IGF1R AKT1 AKT1 ERAS ERAS HSPA1L HSPA1L LOC102734190 LOC102734190 HSPA2 HSPA2 CRYAB CRYAB ATG5 ATG5 PRKAB1 PRKAB1 LOC102749673 LOC102749673 AKT3 AKT3 RPS6KB1 RPS6KB1 FOXA2 FOXA2 PTRHD1 PTRHD1 KRAS KRAS PRKAG2 PRKAG2 LOC102748583 LOC102748583 HDAC2 HDAC2 ADCY9 ADCY9 LOC102746012 LOC102746012 PIK3CD PIK3CD CLPB CLPB PIK3CA PIK3CA LOC102736516 LOC102736516 LOC102741553 LOC102741553 LOC102731850 LOC102731850 INS INS FOXO1 FOXO1 KCNK1 KCNK1 AKT1S1 AKT1S1 RPS6KB2 RPS6KB2 PRKACA PRKACA LOC102731038 LOC102731038 LOC102751021 LOC102751021 LOC102739283 LOC102739283 PRKAG1 PRKAG1 LOC102731213 LOC102731213 LOC102726446 LOC102726446 NRAS NRAS CSDE1 CSDE1 PIK3R3 PIK3R3 LOC102739252 LOC102739252 ADCY6 ADCY6 FOXO3 FOXO3 FOXA1 FOXA1 LOC102729608 LOC102729608 IGF1 IGF1 TIMM8B TIMM8B SOD2 SOD2 PRKAA1 PRKAA1 HDAC1 HDAC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
IRS1Insulin receptor substrate 1-like isoform X1. (1236 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
TIMM8AMitochondrial import inner membrane translocase subunit Tim8 A isoform X2; Belongs to the small Tim family. (97 aa)
IGF1RInsulin-like growth factor 1 receptor-like. (291 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
ERASGTPase ERas. (233 aa)
HSPA1LHeat shock 70 kDa protein 1-like; Belongs to the heat shock protein 70 family. (641 aa)
LOC102734190Heat shock 70 kDa protein 1-like; Belongs to the heat shock protein 70 family. (641 aa)
HSPA2Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (636 aa)
CRYABAlpha-crystallin B chain isoform X1; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (255 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1. (270 aa)
LOC102749673Insulin-like growth factor 1 receptor-like. (143 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
RPS6KB1Non-specific serine/threonine protein kinase. (445 aa)
FOXA2Hepatocyte nuclear factor 3-beta-like. (465 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
KRASGTPase KRas isoform X2. (188 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2-like isoform X2. (327 aa)
LOC1027485835'-AMP-activated protein kinase subunit gamma-2-like. (129 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (790 aa)
LOC102746012Adenylate cyclase type 3-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (311 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
CLPBCaseinolytic peptidase B protein homolog. (319 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
LOC102741553Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (247 aa)
LOC102731850Tyrosine-protein kinase receptor. (757 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
FOXO1Forkhead box protein O1-like. (418 aa)
KCNK1Potassium channel subfamily K member. (336 aa)
AKT1S1Proline-rich AKT1 substrate 1. (276 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC102731038Adenylate cyclase type 9-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (564 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102739283Heat shock cognate 71 kDa protein-like. (196 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (298 aa)
LOC102731213Heat shock cognate 71 kDa protein-like isoform X1; Belongs to the heat shock protein 70 family. (646 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
NRASGTPase NRas. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
LOC102739252Heat shock cognate 71 kDa protein-like. (395 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
FOXO3Forkhead box protein O3. (672 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (473 aa)
LOC102729608Caseinolytic peptidase B protein homolog. (182 aa)
IGF1Insulin-like growth factor I isoform X1. (153 aa)
TIMM8BMitochondrial import inner membrane translocase subunit Tim8 B; Belongs to the small Tim family. (83 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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