STRINGSTRING
MYL12B MYL12B LOC102738234 LOC102738234 RAPGEF6 RAPGEF6 CLDN18 CLDN18 LOC102746429 LOC102746429 LRRC1 LRRC1 CGN CGN MYH11 MYH11 MYL6 MYL6 ESYT1 ESYT1 CFTR CFTR GATA4 GATA4 MAPK10 MAPK10 TJP1 TJP1 LOC102738651 LOC102738651 LOC102740357 LOC102740357 PPP2CB PPP2CB PARD6B PARD6B NEDD4 NEDD4 PRKCZ PRKCZ CGNL1 CGNL1 GATA6 GATA6 LOC102734862 LOC102734862 MSN MSN PRKAA1 PRKAA1 SRC SRC CLDN10 CLDN10 CLDN15 CLDN15 MAP2K7 MAP2K7 LOC102732471 LOC102732471 RAP2A RAP2A DLG2 DLG2 ACTB ACTB MPP5 MPP5 HSPA4 HSPA4 TUBAL3 TUBAL3 CLDN25 CLDN25 PCNA PCNA ACTN1 ACTN1 FRRS1L FRRS1L LOC102737793 LOC102737793 CLDN11 CLDN11 PRKCI PRKCI EPB41L5 EPB41L5 TJAP1 TJAP1 PPP2R2A PPP2R2A CTTN CTTN PRKACB PRKACB AMOTL2 AMOTL2 MYL2 MYL2 DLG3 DLG3 ITGB1 ITGB1 LOC102734673 LOC102734673 MAPK8 MAPK8 WAS WAS VASP VASP MARVELD2 MARVELD2 CLDN7 CLDN7 OCLN OCLN YBX2 YBX2 ACTN4 ACTN4 PRKAB1 PRKAB1 JUN JUN RAPGEF2 RAPGEF2 ROCK2 ROCK2 CDK4 CDK4 CLDN16 CLDN16 LEPREL1 LEPREL1 CLDN1 CLDN1 MAP3K1 MAP3K1 LOC102750359 LOC102750359 LOC102738307 LOC102738307 CD1C CD1C LOC102738001 LOC102738001 LOC102742806 LOC102742806 MICALL1 MICALL1 LOC102733200 LOC102733200 LOC102728451 LOC102728451 LOC102734089 LOC102734089 TUBA8 TUBA8 LOC102744863 LOC102744863 LOC102750652 LOC102750652 MYL9 MYL9 MARVELD3 MARVELD3 PRKAG2 PRKAG2 LOC102748583 LOC102748583 TUBA4A TUBA4A LOC102731290 LOC102731290 PPP2R2C PPP2R2C RAB13 RAB13 JTB JTB TIAM1 TIAM1 LOC102729874 LOC102729874 CLDN2 CLDN2 LOC102729978 LOC102729978 F11R F11R CDC42 CDC42 LOC102739419 LOC102739419 CCND1 CCND1 CLDN14 CLDN14 ACTR3B ACTR3B MYH9 MYH9 LOC102738827 LOC102738827 LOC102737030 LOC102737030 LOC102732031 LOC102732031 ACTL8 ACTL8 LOC102738241 LOC102738241 TMEM237 TMEM237 LOC102736228 LOC102736228 PARD6A PARD6A CRB3 CRB3 LOC102745732 LOC102745732 CLDN19 CLDN19 LOC102743250 LOC102743250 CLDN24 CLDN24 LOC102730930 LOC102730930 LOC102733936 LOC102733936 RDX RDX CLDN4 CLDN4 LOC102730931 LOC102730931 LOC102730629 LOC102730629 LOC102738369 LOC102738369 LOC102742564 LOC102742564 LOC102731549 LOC102731549 LOC102735556 LOC102735556 LOC102744202 LOC102744202 PRKACA PRKACA LOC102738667 LOC102738667 LOC102727190 LOC102727190 LOC102730737 LOC102730737 LOC102730434 LOC102730434 LLGL2 LLGL2 LOC102743809 LOC102743809 LOC102731957 LOC102731957 PRKAG1 PRKAG1 CLDN5 CLDN5 CLDN22 CLDN22 ACTG1 ACTG1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MYL12BMyosin regulatory light chain 12B isoform X1. (172 aa)
LOC102738234Myosin regulatory light polypeptide 9-like isoform X2. (172 aa)
RAPGEF6Rap guanine nucleotide exchange factor 6 isoform X1. (1614 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
LOC102746429Na(+)/H(+) exchange regulatory cofactor NHE-RF1-like. (222 aa)
LRRC1Leucine-rich repeat-containing protein 1. (242 aa)
CGNCingulin. (1197 aa)
MYH11Myosin-11 isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1979 aa)
MYL6Myosin light polypeptide 6 isoform X2. (151 aa)
ESYT1Extended synaptotagmin-1. (1100 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1483 aa)
GATA4Transcription factor GATA-4 isoform X1. (443 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
TJP1Tight junction protein ZO-1 isoform X1; Belongs to the MAGUK family. (1770 aa)
LOC102738651Afadin-like. (267 aa)
LOC102740357Cell division control protein 42 homolog. (191 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
PARD6BPartitioning defective 6 homolog beta. (370 aa)
NEDD4E3 ubiquitin-protein ligase NEDD4 isoform X1. (1323 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (557 aa)
CGNL1Cingulin-like protein 1. (1189 aa)
GATA6Transcription factor GATA-6. (287 aa)
LOC102734862Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
MSNLOW QUALITY PROTEIN: moesin. (546 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
SRCTyrosine-protein kinase. (536 aa)
CLDN10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (232 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
LOC102732471Tubulin alpha-1B chain-like. (134 aa)
RAP2ARas-related protein Rap-2a. (117 aa)
DLG2Disks large homolog 2 isoform X1. (905 aa)
ACTBActin, cytoplasmic 1. (375 aa)
MPP5MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (675 aa)
HSPA4Heat shock 70 kDa protein 4 isoform X1. (839 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (398 aa)
CLDN25Putative claudin-25. (228 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
ACTN1Alpha-actinin-1. (406 aa)
FRRS1LDOMON domain-containing protein FRRS1L. (167 aa)
LOC102737793Ras-related protein Rab-8A-like. (207 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (543 aa)
EPB41L5Band 4.1-like protein 5 isoform X1. (732 aa)
TJAP1Tight junction-associated protein 1 isoform X2. (561 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
CTTNSrc substrate cortactin. (545 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
AMOTL2Angiomotin-like protein 2 isoform X1. (776 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform isoform X1. (166 aa)
DLG3Disks large homolog 3 isoform X1; Belongs to the MAGUK family. (512 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
LOC102734673Myosin-10-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (120 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
WASwiskott-Aldrich syndrome protein. (501 aa)
VASPVasodilator-stimulated phosphoprotein isoform X1; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (382 aa)
MARVELD2MARVEL domain-containing protein 2. (559 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
OCLNOccludin. (271 aa)
YBX2Y-box-binding protein 2. (304 aa)
ACTN4Alpha-actinin-4 isoform X1. (933 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1. (270 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2 isoform X1. (1499 aa)
ROCK2Rho-associated protein kinase 2. (850 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
CLDN16Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa)
LEPREL1Prolyl 3-hydroxylase 2. (533 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1345 aa)
LOC102750359Myosin-9-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (163 aa)
LOC102738307T-cell surface glycoprotein CD1a-like. (340 aa)
CD1CT-cell surface glycoprotein CD1c. (337 aa)
LOC102738001T-cell surface glycoprotein CD1a-like. (339 aa)
LOC102742806T-cell surface glycoprotein CD1b-like. (349 aa)
MICALL1MICAL-like protein 1. (861 aa)
LOC102733200Claudin-9-like. (206 aa)
LOC102728451Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (293 aa)
LOC102734089Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1-like. (154 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC102744863Uncharacterized protein LOC102744863. (211 aa)
LOC102750652Actin-related protein 3-like isoform X1; Belongs to the actin family. (418 aa)
MYL9Myosin regulatory light polypeptide 9 isoform X1. (172 aa)
MARVELD3MARVEL domain-containing protein 3. (376 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2-like isoform X2. (327 aa)
LOC1027485835'-AMP-activated protein kinase subunit gamma-2-like. (129 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
LOC102731290Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform. (231 aa)
RAB13Ras-related protein Rab-13. (203 aa)
JTBProtein JTB. (84 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1 isoform X1. (1591 aa)
LOC102729874Ras-related protein Rap-2a-like. (200 aa)
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
LOC102729978Beta-actin-like protein 2-like isoform X1. (376 aa)
F11RJunctional adhesion molecule A. (298 aa)
CDC42Cell division control protein 42 homolog. (160 aa)
LOC102739419Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (214 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (237 aa)
ACTR3BActin-related protein 3B-like isoform X2; Belongs to the actin family. (286 aa)
MYH9Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1845 aa)
LOC102738827Unconventional myosin-XV-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2226 aa)
LOC102737030Receptor tyrosine-protein kinase erbB-2-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. (627 aa)
LOC102732031Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like. (407 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (366 aa)
LOC102738241Mitogen-activated protein kinase kinase kinase 5-like. (795 aa)
TMEM237Transmembrane protein 237. (403 aa)
LOC102736228Partitioning defective 3 homolog. (214 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (346 aa)
CRB3Protein crumbs homolog 3. (123 aa)
LOC102745732Leucine-rich repeat-containing protein 1-like. (92 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
LOC102743250Transcription factor GATA-5-like. (300 aa)
CLDN24Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
LOC102730930Ras-related protein Rap-2c-like. (183 aa)
LOC102733936MAGUK p55 subfamily member 4-like. (149 aa)
RDXRadixin isoform X1. (572 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
LOC102730931Prolyl 3-hydroxylase 1-like. (349 aa)
LOC102730629Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (288 aa)
LOC102738369Merlin-like. (110 aa)
LOC102742564Rho-associated protein kinase 2-like. (530 aa)
LOC102731549GA-binding protein alpha chain-like. (204 aa)
LOC102735556Mitogen-activated protein kinase 9-like. (134 aa)
LOC102744202Rho GTPase-activating protein 44-like. (155 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC102738667Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1-like. (380 aa)
LOC102727190Serine/threonine-protein kinase STK11-like. (545 aa)
LOC102730737Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
LOC102730434Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
LLGL2Lethal(2) giant larvae protein homolog 2. (1021 aa)
LOC102743809Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
LOC102731957Myosin light chain 6B-like isoform X1. (209 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (298 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (309 aa)
CLDN22Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
ACTG1LOW QUALITY PROTEIN: actin, gamma 1. (411 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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