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PCGF5 PCGF5 LOC102751021 LOC102751021 LOC102734167 LOC102734167 WNT10B WNT10B LOC102744413 LOC102744413 MAPK11 MAPK11 LOC102749847 LOC102749847 LOC102726484 LOC102726484 LOC102740573 LOC102740573 LOC102743476 LOC102743476 INHBE INHBE STAT3 STAT3 INHBC INHBC FGF2 FGF2 LOC102749632 LOC102749632 LOC102730318 LOC102730318 LOC102727485 LOC102727485 LOC102731850 LOC102731850 JAK3 JAK3 WNT2B WNT2B LOC102740547 LOC102740547 LOC102732238 LOC102732238 LOC102750211 LOC102750211 LOC102739552 LOC102739552 JARID2 JARID2 PCGF3 PCGF3 INHBA INHBA LOC102736516 LOC102736516 FZD4 FZD4 TCF3 TCF3 PIK3CA PIK3CA LOC102726140 LOC102726140 NODAL NODAL PIK3CD PIK3CD POU5F2 POU5F2 ID2 ID2 LOC102731813 LOC102731813 WNT4 WNT4 HAND1 HAND1 SMAD1 SMAD1 FZD9 FZD9 WNT3 WNT3 WNT9B WNT9B MAPK1 MAPK1 WNT3A WNT3A WNT11 WNT11 PCGF2 PCGF2 WNT6 WNT6 WNT10A WNT10A LOC102745999 LOC102745999 LEFTY1 LEFTY1 WNT5B WNT5B GSK3B GSK3B LHX5 LHX5 ZIC3 ZIC3 WNT5A WNT5A DUSP9 DUSP9 BMPR1A BMPR1A RAF1 RAF1 FZD10 FZD10 AKT3 AKT3 LOC102749673 LOC102749673 PCGF6 PCGF6 HOXD1 HOXD1 ESRRB ESRRB TBX3 TBX3 LOC102728024 LOC102728024 HOXB1 HOXB1 DVL2 DVL2 FGFR2 FGFR2 MAP2K2 MAP2K2 LOC102730764 LOC102730764 LOC102745161 LOC102745161 POU5F1 POU5F1 ERAS ERAS NANOG NANOG AKT1 AKT1 IGF1R IGF1R DVL3 DVL3 ONECUT1 ONECUT1 LOC102745156 LOC102745156 HESX1 HESX1 JAK2 JAK2 WNT8A WNT8A ONECUT2 ONECUT2 LOC102728433 LOC102728433 FGFR3 FGFR3 LOC102737492 LOC102737492 INHBB INHBB LOC102747185 LOC102747185 PCGF1 PCGF1 FZD2 FZD2 LOC102732274 LOC102732274 MAPK12 MAPK12 FZD3 FZD3 MYF5 MYF5 ACVR1 ACVR1 ISL2 ISL2 ACVR1C ACVR1C SMAD4 SMAD4 BMPR2 BMPR2 FZD7 FZD7 MEIS2 MEIS2 SMAD9 SMAD9 BMPR1B BMPR1B SMARCAD1 SMARCAD1 ACVR2B ACVR2B OTX1 OTX1 FZD5 FZD5 NFIL3 NFIL3 FGFR4 FGFR4 LHX1 LHX1 DVL1 DVL1 AXIN1 AXIN1 ZIC2 ZIC2 LOC102729319 LOC102729319 HOXA1 HOXA1 IGF1 IGF1 LOC102729919 LOC102729919 BMI1 BMI1 MAP2K1 MAP2K1 WNT1 WNT1 PAX6 PAX6 PIK3R3 PIK3R3 CSDE1 CSDE1 NRAS NRAS ZIC1 ZIC1 LOC102733831 LOC102733831 SETDB1 SETDB1 WNT16 WNT16 LOC102726446 LOC102726446 KRAS KRAS ACVR2A ACVR2A ID1 ID1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCGF5Polycomb group RING finger protein 5. (255 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102734167Neurogenin-1-like. (250 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC102744413Left-right determination factor 2-like. (165 aa)
MAPK11Mitogen-activated protein kinase. (254 aa)
LOC102749847Tyrosine-protein kinase JAK1-like. (444 aa)
LOC102726484Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (207 aa)
LOC102740573Transcription factor SOX-3-like. (215 aa)
LOC102743476Leukemia inhibitory factor receptor-like. (231 aa)
INHBEInhibin beta E chain. (351 aa)
STAT3Signal transducer and activator of transcription 3-like. (424 aa)
INHBCInhibin beta C chain. (352 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
LOC102749632Krueppel-like factor 4-like. (414 aa)
LOC102730318Mothers against decapentaplegic homolog. (415 aa)
LOC102727485Homeobox protein Meis1-like. (210 aa)
LOC102731850Tyrosine-protein kinase receptor. (757 aa)
JAK3Tyrosine-protein kinase. (1139 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
LOC102740547Bone morphogenetic protein 4-like isoform X1. (409 aa)
LOC102732238Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (265 aa)
LOC102750211Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (154 aa)
LOC102739552Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
JARID2Protein Jumonji. (1075 aa)
PCGF3Polycomb group RING finger protein 3. (242 aa)
INHBAInhibin beta A chain. (424 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
TCF3Transcription factor E2-alpha isoform X1. (654 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC102726140Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family. (647 aa)
NODALNodal homolog. (348 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
POU5F2POU domain protein. (339 aa)
ID2DNA-binding protein inhibitor ID-2 isoform X2. (134 aa)
LOC102731813Frizzled-6-like; Belongs to the G-protein coupled receptor Fz/Smo family. (400 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (407 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (218 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
PCGF2Polycomb group RING finger protein 2 isoform X1. (371 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (261 aa)
LOC102745999Left-right determination factor 1-like. (203 aa)
LEFTY1Left-right determination factor. (366 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
LHX5LIM/homeobox protein Lhx5. (402 aa)
ZIC3Zinc finger protein ZIC 3. (465 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (380 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
LOC102749673Insulin-like growth factor 1 receptor-like. (143 aa)
PCGF6Polycomb group RING finger protein 6 isoform X1. (349 aa)
HOXD1Homeobox protein Hox-D1. (299 aa)
ESRRBSteroid hormone receptor ERR2. (394 aa)
TBX3T-box transcription factor TBX3. (675 aa)
LOC102728024Homeobox protein SEBOX-like. (311 aa)
HOXB1Homeobox protein Hox-B1. (304 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (734 aa)
FGFR2Fibroblast growth factor receptor 2. (658 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
LOC102730764Mothers against decapentaplegic homolog 2-like. (227 aa)
LOC102745161Signal transducer and activator of transcription 3-like. (301 aa)
POU5F1POU domain protein. (360 aa)
ERASGTPase ERas. (233 aa)
NANOGHomeobox protein NANOG. (226 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
IGF1RInsulin-like growth factor 1 receptor-like. (291 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa)
ONECUT1One cut domain family member. (465 aa)
LOC102745156Catenin beta-1-like isoform X1. (216 aa)
HESX1Homeobox expressed in ES cells 1. (185 aa)
JAK2Tyrosine-protein kinase. (952 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ONECUT2One cut domain family member. (430 aa)
LOC102728433Estrogen-related receptor gamma-like isoform X2. (458 aa)
FGFR3Fibroblast growth factor receptor. (809 aa)
LOC102737492Paired mesoderm homeobox protein 1-like. (245 aa)
INHBBInhibin beta B chain. (320 aa)
LOC102747185Homeobox protein DLX-5-like. (214 aa)
PCGF1Polycomb group RING finger protein 1-like. (259 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
LOC102732274Homeobox protein Meis1-like. (104 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
FZD3Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ISL2LOW QUALITY PROTEIN: insulin gene enhancer protein ISL-2. (363 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (443 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (974 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
MEIS2Homeobox protein Meis2-like isoform X5. (464 aa)
SMAD9Mothers against decapentaplegic homolog. (469 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SMARCAD1annotation not available (1028 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (434 aa)
OTX1Homeobox protein OTX1. (354 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
NFIL3Nuclear factor interleukin-3-regulated protein. (462 aa)
FGFR4Fibroblast growth factor receptor. (800 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (693 aa)
AXIN1Axin-1 isoform X1. (867 aa)
ZIC2Zinc finger protein ZIC 2. (477 aa)
LOC102729319Insulin gene enhancer protein ISL-1-like. (349 aa)
HOXA1Homeobox protein Hox-A1 isoform X1. (332 aa)
IGF1Insulin-like growth factor I isoform X1. (153 aa)
LOC102729919Transcription factor SOX-2-like. (322 aa)
BMI1Polycomb complex protein BMI-1 isoform X1. (326 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
PAX6Paired box protein Pax-6. (221 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
NRASGTPase NRas. (189 aa)
ZIC1Zinc finger protein ZIC 1. (447 aa)
LOC102733831Transcription factor SOX-3-like. (82 aa)
SETDB1Histone-lysine N-methyltransferase SETDB1 isoform X1. (1297 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (149 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
KRASGTPase KRas isoform X2. (188 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
ID1DNA-binding protein inhibitor ID-1. (154 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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