STRINGSTRING
C5 C5 C1R C1R C8A C8A C1QB C1QB C1QC C1QC C5AR2 C5AR2 CFD CFD THBD THBD SERPINF2 SERPINF2 MASP1 MASP1 KLKB1 KLKB1 C9 C9 F9 F9 KNG1 KNG1 SERPINA5 SERPINA5 PLAT PLAT SERPIND1 SERPIND1 LOC102742613 LOC102742613 LOC102742911 LOC102742911 LOC102745401 LOC102745401 LOC102748902 LOC102748902 PROCR PROCR MROH2B MROH2B CPB2 CPB2 SERPINB2 SERPINB2 LOC102726963 LOC102726963 CD59 CD59 LOC102745316 LOC102745316 LOC102729925 LOC102729925 LOC102744722 LOC102744722 LOC102748337 LOC102748337 LOC102737563 LOC102737563 FGB FGB FGG FGG SERPING1 SERPING1 ITGAX ITGAX ITGAM ITGAM LOC102745644 LOC102745644 ZNF408 ZNF408 C4BPA C4BPA LOC102749038 LOC102749038 VTN VTN PLAUR PLAUR SERPINC1 SERPINC1 VSIG4 VSIG4 AADAC AADAC AADACL2 AADACL2 SERPINE1 SERPINE1 LOC102728215 LOC102728215 F13B F13B LOC102744421 LOC102744421 LOC102741183 LOC102741183 F2RL2 F2RL2 F2R F2R MASP2 MASP2 BDKRB2 BDKRB2 VWF VWF C2 C2 CFB CFB F10 F10 C1RL C1RL C1S C1S
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C5Complement C5. (1391 aa)
C1RComplement C1r subcomponent isoform X1; Belongs to the peptidase S1 family. (705 aa)
C8AComplement component C8 alpha chain. (589 aa)
C1QBComplement C1q subcomponent subunit B. (249 aa)
C1QCComplement C1q subcomponent subunit C. (245 aa)
C5AR2C5a anaphylatoxin chemotactic receptor 2. (337 aa)
CFDComplement factor D; Belongs to the peptidase S1 family. (259 aa)
THBDThrombomodulin. (577 aa)
SERPINF2Alpha-2-antiplasmin; Belongs to the serpin family. (415 aa)
MASP1Mannan-binding lectin serine protease 1 isoform X1; Belongs to the peptidase S1 family. (728 aa)
KLKB1Plasma kallikrein; Belongs to the peptidase S1 family. (634 aa)
C9Complement component C9. (217 aa)
F9Coagulation factor IX isoform X1. (459 aa)
KNG1Kininogen-1 isoform X1. (652 aa)
SERPINA5Plasma serine protease inhibitor; Belongs to the serpin family. (416 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (560 aa)
SERPIND1Heparin cofactor 2; Belongs to the serpin family. (116 aa)
LOC102742613Alpha-2-macroglobulin-like. (1480 aa)
LOC102742911Alpha-2-macroglobulin-like. (270 aa)
LOC102745401Venom factor-like. (218 aa)
LOC102748902Complement C3-like. (383 aa)
PROCREndothelial protein C receptor. (241 aa)
MROH2BMaestro heat-like repeat-containing protein family member 2B. (1535 aa)
CPB2Carboxypeptidase B2. (423 aa)
SERPINB2Plasminogen activator inhibitor 2; Belongs to the serpin family. (416 aa)
LOC102726963Granzyme K-like; Belongs to the peptidase S1 family. (268 aa)
CD59CD59 glycoprotein. (120 aa)
LOC102745316Von Willebrand factor-like. (532 aa)
LOC102729925B1 bradykinin receptor-like. (343 aa)
LOC102744722LOW QUALITY PROTEIN: pregnancy zone protein-like. (1064 aa)
LOC102748337Complement factor H-like. (447 aa)
LOC102737563Complement C5-like. (186 aa)
FGBFibrinogen beta chain isoform X1. (484 aa)
FGGFibrinogen gamma chain isoform X1. (445 aa)
SERPING1Plasma protease C1 inhibitor; Belongs to the serpin family. (476 aa)
ITGAXIntegrin alpha-X; Belongs to the integrin alpha chain family. (1166 aa)
ITGAMIntegrin alpha-M isoform X1; Belongs to the integrin alpha chain family. (1154 aa)
LOC102745644Heparin cofactor 2-like isoform X1; Belongs to the serpin family. (296 aa)
ZNF408Zinc finger protein 408. (716 aa)
C4BPAC4b-binding protein alpha chain-like. (598 aa)
LOC102749038Complement factor H-related protein 2-like. (269 aa)
VTNVitronectin. (456 aa)
PLAURUrokinase plasminogen activator surface receptor isoform X1. (335 aa)
SERPINC1antithrombin-III; Belongs to the serpin family. (465 aa)
VSIG4V-set and immunoglobulin domain-containing protein 4 isoform X1. (399 aa)
AADACArylacetamide deacetylase. (399 aa)
AADACL2LOW QUALITY PROTEIN: arylacetamide deacetylase-like 2. (400 aa)
SERPINE1Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa)
LOC102728215Complement C3-like. (768 aa)
F13BCoagulation factor XIII B chain. (660 aa)
LOC102744421Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (812 aa)
LOC102741183Roquin-1-like. (688 aa)
F2RL2Proteinase-activated receptor 3-like. (377 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
MASP2LOW QUALITY PROTEIN: mannan-binding lectin serine protease 2; Belongs to the peptidase S1 family. (722 aa)
BDKRB2B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (392 aa)
VWFVon Willebrand factor. (2285 aa)
C2Complement C2 isoform X1; Belongs to the peptidase S1 family. (748 aa)
CFBComplement factor B; Belongs to the peptidase S1 family. (768 aa)
F10Coagulation factor X; Belongs to the peptidase S1 family. (178 aa)
C1RLComplement C1r subcomponent-like protein; Belongs to the peptidase S1 family. (490 aa)
C1SComplement C1s subcomponent isoform X1; Belongs to the peptidase S1 family. (695 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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