STRINGSTRING
ORAI1 ORAI1 LOC102750303 LOC102750303 ARHGEF12 ARHGEF12 ACTL8 ACTL8 LRRC15 LRRC15 CPN2 CPN2 LOC102736516 LOC102736516 STIM1 STIM1 PLCB3 PLCB3 ARHGAP35 ARHGAP35 PIK3CA PIK3CA PIK3CD PIK3CD LOC102746012 LOC102746012 RASGRP2 RASGRP2 LOC102733909 LOC102733909 LOC102738224 LOC102738224 PTGIR PTGIR ACTG1 ACTG1 LOC102751021 LOC102751021 LOC102740880 LOC102740880 MAPK11 MAPK11 LOC102731038 LOC102731038 LOC102751019 LOC102751019 PRKACA PRKACA LOC102748833 LOC102748833 DGCR6 DGCR6 LOC102742564 LOC102742564 P2RY12 P2RY12 MYLK3 MYLK3 LOC102740654 LOC102740654 LOC102745316 LOC102745316 LOC102730715 LOC102730715 PPP1CA PPP1CA LOC102729496 LOC102729496 ADCY9 ADCY9 FCER1G FCER1G LOC102729978 LOC102729978 LOC102735415 LOC102735415 DHRSX DHRSX TLN1 TLN1 ITPR3 ITPR3 MAPK1 MAPK1 LOC102742813 LOC102742813 RASGRP1 RASGRP1 RDH13 RDH13 TLN2 TLN2 ITPR1 ITPR1 FGB FGB GUCY1B3 GUCY1B3 FGG FGG GUCY1A3 GUCY1A3 LOC102726446 LOC102726446 PIK3R3 PIK3R3 ADCY6 ADCY6 ZNF408 ZNF408 COL1A2 COL1A2 PLA2G4D PLA2G4D SNAP23 SNAP23 ARHGEF1 ARHGEF1 PRKCZ PRKCZ LOC102726697 LOC102726697 LOC102734862 LOC102734862 RDH14 RDH14 SRC SRC ACTB ACTB LOC102735079 LOC102735079 ITGB3 ITGB3 LOC102734178 LOC102734178 MAPK12 MAPK12 F2R F2R LCP2 LCP2 VWF VWF PRKCI PRKCI JMJD7 JMJD7 PRKACB PRKACB PPP1CC PPP1CC GNAI2 GNAI2 PRKG2 PRKG2 ITGB1 ITGB1 BTK BTK ITPR2 ITPR2 AKT1 AKT1 VASP VASP TBXA2R TBXA2R LOC102749767 LOC102749767 LOC102740198 LOC102740198 ROCK2 ROCK2 AKT3 AKT3 RAP1B RAP1B LOC102742903 LOC102742903 PRKG1 PRKG1 PTRHD1 PTRHD1 MESDC1 MESDC1 PPP1CB PPP1CB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ORAI1Calcium release-activated calcium channel protein 1. (302 aa)
LOC102750303Collagen alpha-1(I) chain-like. (395 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12-like. (932 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (366 aa)
LRRC15Leucine-rich repeat-containing protein 15. (580 aa)
CPN2Carboxypeptidase N subunit 2. (547 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
STIM1Stromal interaction molecule 1. (215 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1100 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
LOC102746012Adenylate cyclase type 3-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (311 aa)
RASGRP2RAS guanyl-releasing protein 2 isoform X2. (608 aa)
LOC102733909Fermitin family homolog 3-like. (275 aa)
LOC102738224LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like. (612 aa)
PTGIRProstacyclin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
ACTG1LOW QUALITY PROTEIN: actin, gamma 1. (411 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102740880Nitric oxide synthase, endothelial-like. (619 aa)
MAPK11Mitogen-activated protein kinase. (254 aa)
LOC102731038Adenylate cyclase type 9-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (564 aa)
LOC102751019Talin-1-like. (2016 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC102748833Tyrosine-protein kinase. (375 aa)
DGCR6Protein DGCR6. (105 aa)
LOC102742564Rho-associated protein kinase 2-like. (530 aa)
P2RY12P2Y purinoceptor 12. (339 aa)
MYLK3Myosin light chain kinase 3. (99 aa)
LOC102740654Phosphoinositide 3-kinase regulatory subunit 5-like. (111 aa)
LOC102745316Von Willebrand factor-like. (532 aa)
LOC1027307151-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2-like. (231 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
LOC102729496P2Y purinoceptor 1-like; Belongs to the G-protein coupled receptor 1 family. (374 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (790 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (94 aa)
LOC102729978Beta-actin-like protein 2-like isoform X1. (376 aa)
LOC102735415Phosphoinositide phospholipase C. (309 aa)
DHRSXDehydrogenase/reductase SDR family member on chromosome X. (253 aa)
TLN1Talin-1. (549 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (557 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
LOC102742813Neuroendocrine secretory protein 55-like. (246 aa)
RASGRP1RAS guanyl-releasing protein 1-like isoform X1. (366 aa)
RDH13Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
TLN2Talin-2-like isoform X1. (2542 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (1244 aa)
FGBFibrinogen beta chain isoform X1. (484 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
FGGFibrinogen gamma chain isoform X1. (445 aa)
GUCY1A3Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
ZNF408Zinc finger protein 408. (716 aa)
COL1A2Collagen alpha-2(I) chain. (1365 aa)
PLA2G4DPhospholipase A2. (817 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (912 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (557 aa)
LOC102726697Guanine nucleotide-binding protein G(I) subunit alpha-1-like isoform X1. (354 aa)
LOC102734862Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
RDH14Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa)
SRCTyrosine-protein kinase. (536 aa)
ACTBActin, cytoplasmic 1. (375 aa)
LOC102735079Rho guanine nucleotide exchange factor 12-like. (163 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (852 aa)
LOC102734178Retinol dehydrogenase 12-like. (172 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (427 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
VWFVon Willebrand factor. (2285 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (543 aa)
JMJD7jmjC domain-containing protein 7. (316 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
PRKG2cGMP-dependent protein kinase 2. (553 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
BTKTyrosine-protein kinase. (659 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2-like. (2701 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
VASPVasodilator-stimulated phosphoprotein isoform X1; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (382 aa)
TBXA2RThromboxane A2 receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (343 aa)
LOC102749767Integrin alpha-IIb-like. (534 aa)
LOC102740198Prostaglandin G/H synthase 1-like isoform X1. (340 aa)
ROCK2Rho-associated protein kinase 2. (850 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
LOC102742903Collagen alpha-1(I) chain-like. (1116 aa)
PRKG1cGMP-dependent protein kinase 1. (193 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
MESDC1Mesoderm development candidate 1. (362 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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