STRINGSTRING
LOC102750394 LOC102750394 LOC102737768 LOC102737768 ARPC1B ARPC1B BOLA1 BOLA1 LOC102750306 LOC102750306 LOC102729189 LOC102729189 LOC102736516 LOC102736516 VAV2 VAV2 PIK3CA PIK3CA INPPL1 INPPL1 PIK3CD PIK3CD SPHK2 SPHK2 CRKL CRKL CDC42 CDC42 LOC102735415 LOC102735415 ARPC5L ARPC5L GOLGA2 GOLGA2 NCF1 NCF1 MAPK1 MAPK1 PLD2 PLD2 WASF3 WASF3 RAC2 RAC2 PLD1 PLD1 RPS6KB1 RPS6KB1 RAF1 RAF1 CFL1 CFL1 AKT3 AKT3 PAK1 PAK1 CCDC125 CCDC125 FCGR2B FCGR2B LOC102737664 LOC102737664 LOC102735873 LOC102735873 VASP VASP WAS WAS AKT1 AKT1 ASAP3 ASAP3 ARPC3 ARPC3 JMJD7 JMJD7 VAV3 VAV3 GSN GSN PIP5K1B PIP5K1B MARCKSL1 MARCKSL1 LAT LAT LIMK2 LIMK2 PPAP2A PPAP2A CFL2 CFL2 PLA2G4D PLA2G4D LOC102740357 LOC102740357 ARF6 ARF6 WASF1 WASF1 ARPC5 ARPC5 PIK3R3 PIK3R3 PIP5K1A PIP5K1A LOC102726446 LOC102726446 RPS6KB2 RPS6KB2 LOC102748833 LOC102748833 LOC102748045 LOC102748045 LOC102735070 LOC102735070 PPAP2C PPAP2C LOC102751021 LOC102751021
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102750394Dedicator of cytokinesis protein 1-like. (237 aa)
LOC102737768Actin-related protein 2/3 complex subunit 1A-like. (101 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
BOLA1bolA-like protein 1 isoform X1; Belongs to the BolA/IbaG family. (137 aa)
LOC102750306Golgin subfamily A member 2-like. (84 aa)
LOC102729189Dedicator of cytokinesis protein 5-like. (273 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
VAV2Guanine nucleotide exchange factor VAV2. (357 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1249 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
SPHK2Sphingosine kinase 2 isoform X1. (656 aa)
CRKLCrk-like protein. (303 aa)
CDC42Cell division control protein 42 homolog. (160 aa)
LOC102735415Phosphoinositide phospholipase C. (309 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
GOLGA2Golgin subfamily A member 2-like. (942 aa)
NCF1Neutrophil cytosol factor 1. (380 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
PLD2Phospholipase. (933 aa)
WASF3wiskott-Aldrich syndrome protein family member 3-like. (328 aa)
RAC2Ras-related C3 botulinum toxin substrate 2. (192 aa)
PLD1Phospholipase. (1074 aa)
RPS6KB1Non-specific serine/threonine protein kinase. (445 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
CFL1Cofilin-1 isoform X2; Belongs to the actin-binding proteins ADF family. (219 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
CCDC125Coiled-coil domain-containing protein 125. (513 aa)
FCGR2BLow affinity immunoglobulin gamma Fc region receptor II-b isoform X1. (314 aa)
LOC102737664Gelsolin-like. (513 aa)
LOC102735873Low affinity immunoglobulin gamma Fc region receptor III-like. (232 aa)
VASPVasodilator-stimulated phosphoprotein isoform X1; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (382 aa)
WASwiskott-Aldrich syndrome protein. (501 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
ASAP3LOW QUALITY PROTEIN: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3. (902 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
JMJD7jmjC domain-containing protein 7. (316 aa)
VAV3Guanine nucleotide exchange factor VAV3 isoform X2. (847 aa)
GSNGelsolin. (189 aa)
PIP5K1BPhosphatidylinositol 4-phosphate 5-kinase type-1 beta. (154 aa)
MARCKSL1MARCKS-related protein. (199 aa)
LATLinker for activation of T-cells family member 1. (256 aa)
LIMK2LIM domain kinase 2 isoform X1. (638 aa)
PPAP2ALipid phosphate phosphohydrolase 1 isoform X1. (286 aa)
CFL2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
PLA2G4DPhospholipase A2. (817 aa)
LOC102740357Cell division control protein 42 homolog. (191 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
WASF1wiskott-Aldrich syndrome protein family member 1 isoform X1. (559 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (549 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
LOC102748833Tyrosine-protein kinase. (375 aa)
LOC102748045Proto-oncogene vav-like. (140 aa)
LOC102735070Dedicator of cytokinesis protein 5-like; Belongs to the DOCK family. (294 aa)
PPAP2CLipid phosphate phosphohydrolase 2-like. (288 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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