STRINGSTRING
NGFRAP1 NGFRAP1 CALML4 CALML4 LOC102751021 LOC102751021 LOC102736765 LOC102736765 MAPK11 MAPK11 LOC102733954 LOC102733954 LOC102736146 LOC102736146 LOC102735556 LOC102735556 MATK MATK ARSI ARSI CAMK2A CAMK2A NTF4 NTF4 LOC102729504 LOC102729504 CAMK4 CAMK4 ZNF274 ZNF274 ABL1 ABL1 NTRK1 NTRK1 LOC102740250 LOC102740250 TP73 TP73 NFKBIE NFKBIE LOC102738241 LOC102738241 LOC102736516 LOC102736516 PRDM4 PRDM4 LOC102732719 LOC102732719 PIK3CA PIK3CA PIK3CD PIK3CD CALM3 CALM3 KIDINS220 KIDINS220 CRKL CRKL CDC42 CDC42 LOC102735415 LOC102735415 LOC102750756 LOC102750756 IKBKB IKBKB LOC102728858 LOC102728858 MAPK1 MAPK1 ARHGDIA ARHGDIA PSEN2 PSEN2 GSK3B GSK3B RPS6KA3 RPS6KA3 MAP3K3 MAP3K3 LOC102728244 LOC102728244 CSK CSK MAP3K1 MAP3K1 RAF1 RAF1 RAP1B RAP1B AKT3 AKT3 JUN JUN NFKBIB NFKBIB LOC102741496 LOC102741496 NTRK2 NTRK2 NGF NGF TP53 TP53 MAP2K2 MAP2K2 ERAS ERAS AKT1 AKT1 MAPK8 MAPK8 FASLG FASLG ZFR ZFR CEP152 CEP152 SHC4 SHC4 LOC102728321 LOC102728321 TRAF6 TRAF6 NTF3 NTF3 PTPN11 PTPN11 IRS1 IRS1 MAPK12 MAPK12 GAB1 GAB1 LOC102745146 LOC102745146 SHC1 SHC1 SH2B1 SH2B1 MAP2K7 MAP2K7 CAMK2G CAMK2G NFKB1 NFKB1 LOC102725595 LOC102725595 LOC102738071 LOC102738071 NFKBIA NFKBIA ARHGDIG ARHGDIG MAPK7 MAPK7 LOC102740357 LOC102740357 IRAK4 IRAK4 ATF4 ATF4 MAP2K1 MAP2K1 MAPK10 MAPK10 FOXO3 FOXO3 PIK3R3 PIK3R3 CSDE1 CSDE1 NRAS NRAS LOC102726446 LOC102726446 KRAS KRAS LOC102736922 LOC102736922 RPS6KA6 RPS6KA6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NGFRAP1Protein BEX3 isoform X1. (112 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like 4. (199 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102736765Interleukin-1 receptor-associated kinase 3-like. (125 aa)
MAPK11Mitogen-activated protein kinase. (254 aa)
LOC102733954Calmodulin-like protein 4-like. (119 aa)
LOC1027361463-phosphoinositide-dependent protein kinase 1-like. (216 aa)
LOC102735556Mitogen-activated protein kinase 9-like. (134 aa)
MATKTyrosine-protein kinase. (496 aa)
ARSIArylsulfatase I. (575 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (476 aa)
NTF4Neurotrophin-4; Belongs to the NGF-beta family. (211 aa)
LOC102729504Apoptosis regulator BAX-like. (212 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV. (360 aa)
ZNF274Neurotrophin receptor-interacting factor homolog. (622 aa)
ABL1Tyrosine-protein kinase ABL1-like. (312 aa)
NTRK1Tyrosine-protein kinase receptor. (592 aa)
LOC102740250Melanoma-associated antigen D1-like isoform X2. (781 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa)
NFKBIENF-kappa-B inhibitor epsilon. (361 aa)
LOC102738241Mitogen-activated protein kinase kinase kinase 5-like. (795 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
PRDM4PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (801 aa)
LOC102732719Ribosomal protein S6 kinase alpha-1-like. (200 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
CALM3Calmodulin isoform X1; Belongs to the calmodulin family. (149 aa)
KIDINS220Kinase D-interacting substrate of 220 kDa isoform X2. (1753 aa)
CRKLCrk-like protein. (303 aa)
CDC42Cell division control protein 42 homolog. (160 aa)
LOC102735415Phosphoinositide phospholipase C. (309 aa)
LOC10275075614-3-3 protein epsilon-like; Belongs to the 14-3-3 family. (233 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
LOC102728858Fibroblast growth factor receptor substrate 2-like; Belongs to the TCP-1 chaperonin family. (251 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
ARHGDIARho GDP-dissociation inhibitor 1 isoform X1. (204 aa)
PSEN2Presenilin-2. (115 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (600 aa)
LOC102728244Interleukin-1 receptor-associated kinase 1-like. (299 aa)
CSKTyrosine-protein kinase. (450 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1345 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
NFKBIBNF-kappa-B inhibitor beta isoform X2. (354 aa)
LOC102741496BDNF/NT-3 growth factors receptor-like. (97 aa)
NTRK2BDNF/NT-3 growth factors receptor-like. (420 aa)
NGFBeta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
ERASGTPase ERas. (233 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
FASLGTumor necrosis factor ligand superfamily member 6. (130 aa)
ZFRZinc finger RNA-binding protein isoform X1. (1073 aa)
CEP152Centrosomal protein of 152 kDa isoform X1. (1723 aa)
SHC4SHC-transforming protein 4. (630 aa)
LOC102728321High affinity nerve growth factor receptor-like. (109 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (541 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (257 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
IRS1Insulin receptor substrate 1-like isoform X1. (1236 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (724 aa)
LOC102745146Tumor necrosis factor ligand superfamily member 6-like; Belongs to the tumor necrosis factor family. (173 aa)
SHC1SHC-transforming protein 1 isoform X2. (583 aa)
SH2B1SH2B adapter protein 1 isoform X3. (688 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (574 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (254 aa)
LOC102725595Fibroblast growth factor receptor substrate 2-like. (316 aa)
LOC102738071Calmodulin-like; Belongs to the calmodulin family. (113 aa)
NFKBIANF-kappa-B inhibitor alpha isoform X2. (314 aa)
ARHGDIGRho GDP-dissociation inhibitor 3. (220 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
LOC102740357Cell division control protein 42 homolog. (191 aa)
IRAK4Interleukin-1 receptor-associated kinase 4 isoform X1. (459 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
FOXO3Forkhead box protein O3. (672 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
NRASGTPase NRas. (189 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
KRASGTPase KRas isoform X2. (188 aa)
LOC102736922Calmodulin-like; Belongs to the calmodulin family. (223 aa)
RPS6KA6Ribosomal protein S6 kinase. (744 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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