STRINGSTRING
PTGS2 PTGS2 LOC102742596 LOC102742596 GNAI2 GNAI2 HTR1D HTR1D GNB3 GNB3 HTR7 HTR7 ITPR2 ITPR2 HTR3C HTR3C ALOX12B ALOX12B CACNA1F CACNA1F ERAS ERAS ALOX15B ALOX15B GNG13 GNG13 LOC102740198 LOC102740198 LOC102745475 LOC102745475 RAF1 RAF1 LOC102734981 LOC102734981 GNGT2 GNGT2 ITPR1 ITPR1 LOC102747983 LOC102747983 HTR1A HTR1A LOC102742813 LOC102742813 PELP1 PELP1 ALOX12 ALOX12 MAPK1 MAPK1 ITPR3 ITPR3 APP APP TPH2 TPH2 CASP3 CASP3 GNG8 GNG8 SLC18A1 SLC18A1 LOC102736718 LOC102736718 GNG4 GNG4 PLCB3 PLCB3 GNG2 GNG2 KCNJ9 KCNJ9 HTR1E HTR1E GNAO1 GNAO1 KCNJ6 KCNJ6 LOC102748816 LOC102748816 TPH1 TPH1 LOC102730715 LOC102730715 HTR4 HTR4 GNB4 GNB4 LOC102748147 LOC102748147 LOC102749347 LOC102749347 PRKACA PRKACA GNG5 GNG5 PRKACB PRKACB JMJD7 JMJD7 MAOA MAOA MAOB MAOB HTR3A HTR3A SLC6A4 SLC6A4 HTR2B HTR2B GNB2 GNB2 GNG10 GNG10 GNB5 GNB5 LOC102726697 LOC102726697 GNG11 GNG11 GNGT1 GNGT1 HTR6 HTR6 KCNJ3 KCNJ3 TRPC1 TRPC1 PLA2G4D PLA2G4D KCNJ5 KCNJ5 GABRB2 GABRB2 GNG3 GNG3 LOC102747630 LOC102747630 HTR5A HTR5A CSDE1 CSDE1 NRAS NRAS HTR2C HTR2C GABRB3 GABRB3 ALOX5 ALOX5 KRAS KRAS LOC102743643 LOC102743643 HTR1F HTR1F
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTGS2Prostaglandin G/H synthase 2. (470 aa)
LOC102742596Cytochrome P450 2W1-like; Belongs to the cytochrome P450 family. (501 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
HTR1D5-hydroxytryptamine receptor 1D. (377 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
HTR75-hydroxytryptamine receptor 7. (435 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2-like. (2701 aa)
HTR3C5-hydroxytryptamine receptor 3C-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (430 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R-type. (699 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1983 aa)
ERASGTPase ERas. (233 aa)
ALOX15BArachidonate 15-lipoxygenase B. (502 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
LOC102740198Prostaglandin G/H synthase 1-like isoform X1. (340 aa)
LOC102745475Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like isoform X1. (340 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LOC102734981Gamma-aminobutyric acid receptor subunit beta-1-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (295 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (1244 aa)
LOC102747983Cytochrome P450 2J2-like; Belongs to the cytochrome P450 family. (445 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
LOC102742813Neuroendocrine secretory protein 55-like. (246 aa)
PELP1Proline-, glutamic acid- and leucine-rich protein 1 isoform X2. (984 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S-type. (663 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (557 aa)
APPAmyloid beta A4 protein. (753 aa)
TPH2Tryptophan 5-hydroxylase 2 isoform X1. (491 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (302 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
SLC18A1Chromaffin granule amine transporter isoform X1. (525 aa)
LOC102736718Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1100 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
KCNJ9G protein-activated inward rectifier potassium channel 3. (385 aa)
HTR1E5-hydroxytryptamine receptor 1E. (365 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (311 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2-like. (407 aa)
LOC1027488165-hydroxytryptamine receptor 2A-like; Belongs to the G-protein coupled receptor 1 family. (204 aa)
TPH1Tryptophan 5-hydroxylase 1. (444 aa)
LOC1027307151-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2-like. (231 aa)
HTR45-hydroxytryptamine receptor 4-like; Belongs to the G-protein coupled receptor 1 family. (388 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
LOC102748147Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC1027493475-hydroxytryptamine receptor 5B-like. (370 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
JMJD7jmjC domain-containing protein 7. (316 aa)
MAOAAmine oxidase. (527 aa)
MAOBAmine oxidase. (504 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
HTR2B5-hydroxytryptamine receptor 2B. (526 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1. (340 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (345 aa)
LOC102726697Guanine nucleotide-binding protein G(I) subunit alpha-1-like isoform X1. (354 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
HTR65-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (440 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
TRPC1Short transient receptor potential channel 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
PLA2G4DPhospholipase A2. (817 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4. (430 aa)
GABRB2Gamma-aminobutyric acid receptor subunit beta-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (364 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC1027476305-hydroxytryptamine receptor 1B-like. (389 aa)
HTR5A5-hydroxytryptamine receptor 5A. (358 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
NRASGTPase NRas. (189 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
GABRB3Gamma-aminobutyric acid receptor subunit beta-3-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (388 aa)
ALOX5Arachidonate 5-lipoxygenase isoform X1. (674 aa)
KRASGTPase KRas isoform X2. (188 aa)
LOC102743643Gamma-aminobutyric acid receptor subunit beta-1-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (209 aa)
HTR1F5-hydroxytryptamine receptor 1F. (366 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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