STRINGSTRING
PPP2R2C PPP2R2C LOC102736922 LOC102736922 PPP2R3A PPP2R3A MAPK10 MAPK10 ATF4 ATF4 GNG3 GNG3 KCNJ5 KCNJ5 PPP2CB PPP2CB KCNJ3 KCNJ3 LOC102738071 LOC102738071 DRD1 DRD1 GRIA2 GRIA2 GNGT1 GNGT1 GNG11 GNG11 LOC102726697 LOC102726697 GNB5 GNB5 CREB1 CREB1 CAMK2G CAMK2G GNG10 GNG10 GNB2 GNB2 GRIN2A GRIN2A LOC102744630 LOC102744630 MAPK12 MAPK12 MAOB MAOB MAOA MAOA PPP2R5D PPP2R5D PPP2R2A PPP2R2A PRKACB PRKACB GNG5 GNG5 PPP1CC PPP1CC GNAI2 GNAI2 GNB3 GNB3 ITPR2 ITPR2 MAPK8 MAPK8 AKT1 AKT1 ATF6B ATF6B CREB3L3 CREB3L3 GNG13 GNG13 LOC102745475 LOC102745475 AKT3 AKT3 LOC102736905 LOC102736905 PPP2R5C PPP2R5C GNGT2 GNGT2 PPP1CB PPP1CB DRD4 DRD4 ITPR1 ITPR1 ATF2 ATF2 GSK3B GSK3B LOC102742813 LOC102742813 LOC102730586 LOC102730586 CLOCK CLOCK CALML4 CALML4 LOC102739577 LOC102739577 MAPK11 MAPK11 LOC102733954 LOC102733954 PRKACA PRKACA LOC102735556 LOC102735556 ARSI ARSI CAMK2A CAMK2A LOC102730629 LOC102730629 LOC102748147 LOC102748147 PPP1R1B PPP1R1B GSK3A GSK3A GNB4 GNB4 TH TH LOC102734642 LOC102734642 LOC102730715 LOC102730715 PPP1CA PPP1CA GNAL GNAL PPP2R3B PPP2R3B COMT COMT LOC102747249 LOC102747249 DRD3 DRD3 CREB3L1 CREB3L1 GRIA1 GRIA1 KCNJ6 KCNJ6 GNAO1 GNAO1 LOC102748609 LOC102748609 KCNJ9 KCNJ9 LOC102732031 LOC102732031 DRD5 DRD5 GNG2 GNG2 PLCB3 PLCB3 CALY CALY GNG4 GNG4 LOC102736718 LOC102736718 FOS FOS LOC102731602 LOC102731602 ARNTL ARNTL LOC102739131 LOC102739131 SLC18A1 SLC18A1 PPP2R5E PPP2R5E CALM3 CALM3 GNG8 GNG8 PPP2R5A PPP2R5A ITPR3 ITPR3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform. (231 aa)
LOC102736922Calmodulin-like; Belongs to the calmodulin family. (223 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1. (1153 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4. (430 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
LOC102738071Calmodulin-like; Belongs to the calmodulin family. (113 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
GRIA2Glutamate receptor 2 isoform X1. (940 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC102726697Guanine nucleotide-binding protein G(I) subunit alpha-1-like isoform X1. (354 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (345 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (574 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1. (340 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1308 aa)
LOC102744630D(2) dopamine receptor-like. (298 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
MAOBAmine oxidase. (504 aa)
MAOAAmine oxidase. (527 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (676 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2-like. (2701 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta. (623 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (466 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
LOC102745475Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like isoform X1. (340 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
LOC102736905Glutamate receptor 3-like. (89 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
DRD4D(4) dopamine receptor. (220 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (1244 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
LOC102742813Neuroendocrine secretory protein 55-like. (246 aa)
LOC102730586Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (624 aa)
CLOCKLOW QUALITY PROTEIN: clock circadian regulator. (846 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like 4. (199 aa)
LOC102739577Leucine-rich repeat-containing protein 51-like isoform X1. (192 aa)
MAPK11Mitogen-activated protein kinase. (254 aa)
LOC102733954Calmodulin-like protein 4-like. (119 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC102735556Mitogen-activated protein kinase 9-like. (134 aa)
ARSIArylsulfatase I. (575 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (476 aa)
LOC102730629Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (288 aa)
LOC102748147Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PPP1R1BProtein phosphatase 1 regulatory subunit 1B. (205 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (419 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
THTyrosine 3-monooxygenase. (307 aa)
LOC102734642Guanine nucleotide-binding protein G(Olf) subunit alpha-like. (209 aa)
LOC1027307151-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2-like. (231 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
GNALGuanine nucleotide-binding protein G(Olf) subunit alpha. (174 aa)
PPP2R3BSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (596 aa)
COMTCatechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (270 aa)
LOC102747249Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (271 aa)
DRD3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (474 aa)
GRIA1Glutamate receptor 1-like; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (528 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2-like. (407 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (311 aa)
LOC102748609Sodium-dependent dopamine transporter-like. (364 aa)
KCNJ9G protein-activated inward rectifier potassium channel 3. (385 aa)
LOC102732031Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like. (407 aa)
DRD5D(1B) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (432 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1100 aa)
CALYNeuron-specific vesicular protein calcyon. (221 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC102736718Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
LOC102731602Transmembrane O-methyltransferase-like. (258 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X5. (583 aa)
LOC102739131D(2) dopamine receptor-like; Belongs to the G-protein coupled receptor 1 family. (198 aa)
SLC18A1Chromaffin granule amine transporter isoform X1. (525 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
CALM3Calmodulin isoform X1; Belongs to the calmodulin family. (149 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (557 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (36%) [HD]