STRINGSTRING
HTR1F HTR1F GABRA2 GABRA2 GABRA4 GABRA4 GABRA5 GABRA5 P2RX3 P2RX3 PDE1B PDE1B ADCY6 ADCY6 LOC102747630 LOC102747630 GABRA6 GABRA6 GABRA1 GABRA1 SCNN1G SCNN1G SCNN1B SCNN1B LOC102744002 LOC102744002 HTR3A HTR3A SCN2A SCN2A LOC102728737 LOC102728737 SCN9A SCN9A GRM1 GRM1 PRKACB PRKACB HTR1D HTR1D GNB3 GNB3 HTR3C HTR3C KCNK5 KCNK5 GNG13 GNG13 CALHM1 CALHM1 HTR1A HTR1A P2RX2 P2RX2 PLCB3 PLCB3 LOC102732327 LOC102732327 HTR1E HTR1E PKD1L2 PKD1L2 P2RY4 P2RY4 LOC102734033 LOC102734033 LOC102729496 LOC102729496 LOC102730715 LOC102730715 PRKACA PRKACA LOC102732556 LOC102732556 LOC102727998 LOC102727998 LOC102740473 LOC102740473
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HTR1F5-hydroxytryptamine receptor 1F. (366 aa)
GABRA2Gamma-aminobutyric acid receptor subunit alpha-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
GABRA4Gamma-aminobutyric acid receptor subunit alpha-4 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (555 aa)
GABRA5Gamma-aminobutyric acid receptor subunit alpha-5; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
P2RX3P2X purinoceptor 3. (147 aa)
PDE1BPhosphodiesterase. (535 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
LOC1027476305-hydroxytryptamine receptor 1B-like. (389 aa)
GABRA6Gamma-aminobutyric acid receptor subunit alpha-6; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
GABRA1Gamma-aminobutyric acid receptor subunit alpha-1 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (649 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (641 aa)
LOC102744002Taste receptor type 2. (318 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (483 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
LOC102728737Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1509 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
GRM1Metabotropic glutamate receptor 1. (887 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
HTR1D5-hydroxytryptamine receptor 1D. (377 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
HTR3C5-hydroxytryptamine receptor 3C-like; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (430 aa)
KCNK5Potassium channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (499 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
CALHM1Calcium homeostasis modulator protein 1. (357 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (471 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1100 aa)
LOC102732327Taste receptor type 2 member 38-like; Belongs to the G-protein coupled receptor T2R family. (383 aa)
HTR1E5-hydroxytryptamine receptor 1E. (365 aa)
PKD1L2LOW QUALITY PROTEIN: polycystic kidney disease protein 1-like 2. (2241 aa)
P2RY4P2Y purinoceptor 4; Belongs to the G-protein coupled receptor 1 family. (365 aa)
LOC102734033Guanine nucleotide-binding protein G(T) subunit alpha-3-like. (163 aa)
LOC102729496P2Y purinoceptor 1-like; Belongs to the G-protein coupled receptor 1 family. (374 aa)
LOC1027307151-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2-like. (231 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC102732556Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
LOC102727998P2X purinoceptor 3-like. (281 aa)
LOC102740473Taste receptor type 2 member 7-like; Belongs to the G-protein coupled receptor T2R family. (258 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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