(76 nodes) Inflammatory mediator regulation of TRP channels network (Leptonychotes weddellii)

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second shell of interactors

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Predicted Interactions

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Your Input:
	LOC102728321	High affinity nerve growth factor receptor-like. (109 aa)
	BDKRB2	B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (392 aa)
	PTGER2	Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	TRPA1	Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family. (1120 aa)
	F2RL1	Proteinase-activated receptor 2. (415 aa)
	MAPK12	Mitogen-activated protein kinase. (367 aa)
	ASIC1	Acid-sensing ion channel 1-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (537 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
	HTR2B	5-hydroxytryptamine receptor 2B. (526 aa)
	HRH1	Histamine H1 receptor; Belongs to the G-protein coupled receptor 1 family. (487 aa)
	SRC	Tyrosine-protein kinase. (536 aa)
	CAMK2G	Calcium/calmodulin-dependent protein kinase type II subunit gamma. (574 aa)
	PTGER4	Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (489 aa)
	AADACL2	LOW QUALITY PROTEIN: arylacetamide deacetylase-like 2. (400 aa)
	AADAC	Arylacetamide deacetylase. (399 aa)
	TRPM8	Transient receptor potential cation channel subfamily M member 8. (1104 aa)
	LOC102738071	Calmodulin-like; Belongs to the calmodulin family. (113 aa)
	MAP2K6	Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
	PLA2G4D	Phospholipase A2. (817 aa)
	IGF1	Insulin-like growth factor I isoform X1. (153 aa)
	LOC102747252	Protein kinase C eta type-like. (89 aa)
	MAPK10	Mitogen-activated protein kinase. (464 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
	PIK3R3	Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
	HTR2C	5-hydroxytryptamine receptor 2C. (458 aa)
	LOC102726446	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
	ASIC5	Acid-sensing ion channel 5; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (505 aa)
	LOC102736922	Calmodulin-like; Belongs to the calmodulin family. (223 aa)
	ASIC4	LOW QUALITY PROTEIN: acid-sensing (Proton-gated) ion channel family member 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (322 aa)
	CALML4	LOW QUALITY PROTEIN: calmodulin-like 4. (199 aa)
	ASIC3	Acid-sensing ion channel 3; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (533 aa)
	LOC102751021	Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
	LOC102736045	Cytochrome P450 4A11-like. (350 aa)
	MAPK11	Mitogen-activated protein kinase. (254 aa)
	LOC102731038	Adenylate cyclase type 9-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (564 aa)
	LOC102733954	Calmodulin-like protein 4-like. (119 aa)
	PRKACA	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
	LOC102735556	Mitogen-activated protein kinase 9-like. (134 aa)
	LOC102729925	B1 bradykinin receptor-like. (343 aa)
	ARSI	Arylsulfatase I. (575 aa)
	CAMK2A	Calcium/calmodulin-dependent protein kinase type II subunit alpha. (476 aa)
	P2RY2	P2Y purinoceptor 2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	LOC102742650	Acid-sensing ion channel 2-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (205 aa)
	LOC102730715	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2-like. (231 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
	NTRK1	Tyrosine-protein kinase receptor. (592 aa)
	LOC102748816	5-hydroxytryptamine receptor 2A-like; Belongs to the G-protein coupled receptor 1 family. (204 aa)
	LOC102736516	Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
	LOC102742727	Transient receptor potential cation channel subfamily V member 1-like. (267 aa)
	MAP2K3	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
	TRPV3	Transient receptor potential cation channel subfamily V member 3; Belongs to the transient receptor (TC 1.A.4) family. (605 aa)
	PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1100 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
	LOC102746012	Adenylate cyclase type 3-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (311 aa)
	CALM3	Calmodulin isoform X1; Belongs to the calmodulin family. (149 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (270 aa)
	ADCY9	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (790 aa)
	LOC102735415	Phosphoinositide phospholipase C. (309 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (557 aa)
	ALOX12	Arachidonate 12-lipoxygenase, 12S-type. (663 aa)
	KNG1	Kininogen-1 isoform X1. (652 aa)
	LOC102742813	Neuroendocrine secretory protein 55-like. (246 aa)
	TRPV4	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (742 aa)
	LOC102747983	Cytochrome P450 2J2-like; Belongs to the cytochrome P450 family. (445 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1. (1244 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	PTRHD1	Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
	LOC102732295	Acid-sensing ion channel 4-like; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (428 aa)
	NGF	Beta-nerve growth factor; Belongs to the NGF-beta family. (241 aa)
	MAPK8	Mitogen-activated protein kinase. (427 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2-like. (2701 aa)
	LOC102742596	Cytochrome P450 2W1-like; Belongs to the cytochrome P450 family. (501 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
	JMJD7	jmjC domain-containing protein 7. (316 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AADAC	BDKRB2	A0A2U3XPD4	A0A2U3XWT1	Arylacetamide deacetylase.	B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family.	0.810
AADAC	LOC102729925	A0A2U3XPD4	A0A2U3Z574	Arylacetamide deacetylase.	B1 bradykinin receptor-like.	0.832
AADACL2	BDKRB2	A0A2U3XPD8	A0A2U3XWT1	LOW QUALITY PROTEIN: arylacetamide deacetylase-like 2.	B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family.	0.810
AADACL2	LOC102729925	A0A2U3XPD8	A0A2U3Z574	LOW QUALITY PROTEIN: arylacetamide deacetylase-like 2.	B1 bradykinin receptor-like.	0.832
ADCY6	ADCY9	A0A2U3XDB9	A0A2U3YLR7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.920
ADCY6	CALM3	A0A2U3XDB9	A0A2U3YN48	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin isoform X1; Belongs to the calmodulin family.	0.826
ADCY6	CALML4	A0A2U3XDB9	A0A2U3Z8V7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	LOW QUALITY PROTEIN: calmodulin-like 4.	0.858
ADCY6	CAMK2A	A0A2U3XDB9	A0A2U3Z4L3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin-dependent protein kinase type II subunit alpha.	0.822
ADCY6	CAMK2G	A0A2U3XDB9	A0A2U3XQ41	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calcium/calmodulin-dependent protein kinase type II subunit gamma.	0.812
ADCY6	LOC102731038	A0A2U3XDB9	A0A2U3Z797	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.842
ADCY6	LOC102733954	A0A2U3XDB9	A0A2U3Z6Q3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like protein 4-like.	0.437
ADCY6	LOC102736922	A0A2U3XDB9	A0A2U3X6F5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like; Belongs to the calmodulin family.	0.482
ADCY6	LOC102738071	A0A2U3XDB9	A0A2U3XLG6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Calmodulin-like; Belongs to the calmodulin family.	0.826
ADCY6	LOC102742813	A0A2U3XDB9	A0A2U3YGK0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Neuroendocrine secretory protein 55-like.	0.810
ADCY6	LOC102746012	A0A2U3XDB9	A0A2U3YPK1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.895
ADCY6	PLCB3	A0A2U3XDB9	A0A2U3YRT9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.500
ADCY6	PRKACA	A0A2U3XDB9	A0A2U3Z6A9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.919
ADCY6	PRKACB	A0A2U3XDB9	A0A2U3XZU0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.928
ADCY6	PRKCQ	A0A2U3XDB9	A0A2U3XTI0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.552
ADCY6	PTRHD1	A0A2U3XDB9	A0A2U3YCC1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Putative peptidyl-tRNA hydrolase PTRHD1.	0.797