STRINGSTRING
PRKACB PRKACB GCG GCG KCNN2 KCNN2 KCNN1 KCNN1 RAB3A RAB3A PLCB3 PLCB3 CCK CCK ATP1B4 ATP1B4 KCNMB3 KCNMB3 KCNMB2 KCNMB2 LOC102746012 LOC102746012 GNA11 GNA11 ADCY9 ADCY9 FXYD2 FXYD2 LOC102733505 LOC102733505 STX1A STX1A ATP1A4 ATP1A4 ATP1A2 ATP1A2 FFAR1 FFAR1 LOC102742813 LOC102742813 ATF2 ATF2 RAPGEF4 RAPGEF4 PTRHD1 PTRHD1 CCKAR CCKAR ATP1B1 ATP1B1 ATP1B2 ATP1B2 CREB3L3 CREB3L3 ATF6B ATF6B CACNA1F CACNA1F ATP1B3 ATP1B3 CREB3L1 CREB3L1 LOC102737493 LOC102737493 LOC102731168 LOC102731168 GCK GCK KCNMB1 KCNMB1 KCNN3 KCNN3 CAMK2G CAMK2G CREB1 CREB1 KCNMB4 KCNMB4 RAB3B RAB3B ATP1A3 ATP1A3 KCNN4 KCNN4 ATF4 ATF4 ADCY6 ADCY6 RAB3C RAB3C ADCYAP1 ADCYAP1 LOC102730991 LOC102730991 LOC102739372 LOC102739372 LOC102731038 LOC102731038 LOC102748835 LOC102748835 PCLO PCLO LOC102732556 LOC102732556 PRKACA PRKACA ARSI ARSI CAMK2A CAMK2A INS INS LOC102730715 LOC102730715 KCNJ11 KCNJ11 PDX1 PDX1 LOC102735730 LOC102735730 SLC2A2 SLC2A2 ATP1A1 ATP1A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
GCGGlucagon isoform X1. (180 aa)
KCNN2Small conductance calcium-activated potassium channel protein 2-like isoform X1. (580 aa)
KCNN1Small conductance calcium-activated potassium channel protein 1. (437 aa)
RAB3ARas-related protein Rab-3A. (220 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1100 aa)
CCKCholecystokinin. (116 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (360 aa)
KCNMB3LOW QUALITY PROTEIN: calcium-activated potassium channel subunit beta-3. (281 aa)
KCNMB2Calcium-activated potassium channel subunit beta-2. (235 aa)
LOC102746012Adenylate cyclase type 3-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (311 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (790 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
LOC102733505Glucose-dependent insulinotropic receptor-like; Belongs to the G-protein coupled receptor 1 family. (335 aa)
STX1Asyntaxin-1A; Belongs to the syntaxin family. (259 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
FFAR1Free fatty acid receptor 1. (299 aa)
LOC102742813Neuroendocrine secretory protein 55-like. (246 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
RAPGEF4Rap guanine nucleotide exchange factor 4 isoform X1. (858 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
CCKARCholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. (428 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (466 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta. (623 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1983 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (474 aa)
LOC102737493Synaptosomal-associated protein; Belongs to the SNAP-25 family. (143 aa)
LOC102731168LOW QUALITY PROTEIN: potassium channel subfamily U member 1-like. (1171 aa)
GCKPhosphotransferase. (391 aa)
KCNMB1Calcium-activated potassium channel subunit beta-1. (191 aa)
KCNN3Small conductance calcium-activated potassium channel protein 3. (697 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (574 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
KCNMB4Calcium-activated potassium channel subunit beta-4. (210 aa)
RAB3BRas-related protein Rab-3B. (179 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
KCNN4Intermediate conductance calcium-activated potassium channel protein 4. (427 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
RAB3CRas-related protein Rab-3C. (219 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide. (176 aa)
LOC102730991Ras-related protein Rab-3B-like. (219 aa)
LOC102739372Seprase-like. (102 aa)
LOC102731038Adenylate cyclase type 9-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (564 aa)
LOC102748835Glucagon-like peptide 1 receptor-like; Belongs to the G-protein coupled receptor 2 family. (368 aa)
PCLOProtein piccolo-like. (1251 aa)
LOC102732556Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
ARSIArylsulfatase I. (575 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (476 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
LOC1027307151-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2-like. (231 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11. (390 aa)
PDX1Pancreas/duodenum homeobox protein 1. (283 aa)
LOC102735730Sodium/potassium-transporting ATPase subunit alpha-1-like; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (346 aa)
SLC2A2Solute carrier family 2, facilitated glucose transporter member 2 isoform X1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (524 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (673 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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