STRINGSTRING
JUN JUN ACTG1 ACTG1 CALML4 CALML4 PRKAG1 PRKAG1 LOC102731957 LOC102731957 LOC102740880 LOC102740880 LOC102731038 LOC102731038 LOC102748949 LOC102748949 LOC102733954 LOC102733954 PRKACA PRKACA CDKN1A CDKN1A LOC102742564 LOC102742564 ARSI ARSI CAMK2A CAMK2A SLC39A12 SLC39A12 MYLK3 MYLK3 LOC102740654 LOC102740654 CAMK4 CAMK4 LOC102730715 LOC102730715 PPP1CA PPP1CA LOC102746542 LOC102746542 NPR1 NPR1 ACTL8 ACTL8 KCNJ6 KCNJ6 GNAO1 GNAO1 KCNJ4 KCNJ4 KCNJ9 KCNJ9 PLCB3 PLCB3 LOC102725943 LOC102725943 CACNG2 CACNG2 NFATC1 NFATC1 FOS FOS LOC102746012 LOC102746012 KCNJ14 KCNJ14 CALM3 CALM3 LOC102738224 LOC102738224 MEF2C MEF2C CCND1 CCND1 ADCY9 ADCY9 LOC102729978 LOC102729978 NPR2 NPR2 ITPR3 ITPR3 MAPK1 MAPK1 CACNB1 CACNB1 LOC102748583 LOC102748583 LOC102742813 LOC102742813 PRKAG2 PRKAG2 CACNA2D4 CACNA2D4 ITPR1 ITPR1 LOC102731583 LOC102731583 PPP1CB PPP1CB PTRHD1 PTRHD1 LOC102727336 LOC102727336 RAF1 RAF1 ROCK2 ROCK2 GPR150 GPR150 PRKAB1 PRKAB1 MAP2K2 MAP2K2 EEF2 EEF2 ERAS ERAS CACNA1F CACNA1F ITPR2 ITPR2 GNAI2 GNAI2 CACNG6 CACNG6 CACNG7 CACNG7 CAMKK2 CAMKK2 PPP1CC PPP1CC PRKACB PRKACB JMJD7 JMJD7 OXTR OXTR CACNB2 CACNB2 NPPA NPPA ACTB ACTB SRC SRC CAMK1G CAMK1G CAMK2G CAMK2G PRKAA1 PRKAA1 LOC102734862 LOC102734862 LOC102726697 LOC102726697 LOC102738071 LOC102738071 KCNJ3 KCNJ3 KCNJ2 KCNJ2 MAPK7 MAPK7 PLA2G4D PLA2G4D KCNJ5 KCNJ5 PTGS2 PTGS2 EEF2K EEF2K NFATC3 NFATC3 PPP3R1 PPP3R1 MAP2K1 MAP2K1 CACNG4 CACNG4 CACNG1 CACNG1 CACNG5 CACNG5 ADCY6 ADCY6 CACNB3 CACNB3 MYL6 MYL6 CSDE1 CSDE1 RGS2 RGS2 NRAS NRAS KRAS KRAS PPP3R2 PPP3R2 GUCY1A3 GUCY1A3 GUCY1B3 GUCY1B3 CACNA2D1 CACNA2D1 LOC102736922 LOC102736922
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
ACTG1LOW QUALITY PROTEIN: actin, gamma 1. (411 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like 4. (199 aa)
PRKAG15'-AMP-activated protein kinase subunit gamma-1 isoform X1. (298 aa)
LOC102731957Myosin light chain 6B-like isoform X1. (209 aa)
LOC102740880Nitric oxide synthase, endothelial-like. (619 aa)
LOC102731038Adenylate cyclase type 9-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (564 aa)
LOC102748949Calcipressin-1-like. (140 aa)
LOC102733954Calmodulin-like protein 4-like. (119 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (161 aa)
LOC102742564Rho-associated protein kinase 2-like. (530 aa)
ARSIArylsulfatase I. (575 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (476 aa)
SLC39A12Zinc transporter ZIP12. (366 aa)
MYLK3Myosin light chain kinase 3. (99 aa)
LOC102740654Phosphoinositide 3-kinase regulatory subunit 5-like. (111 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV. (360 aa)
LOC1027307151-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2-like. (231 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
LOC102746542Transient receptor potential cation channel subfamily M member 2-like. (677 aa)
NPR1Atrial natriuretic peptide receptor 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (242 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (366 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2-like. (407 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (311 aa)
KCNJ4Inward rectifier potassium channel 4. (451 aa)
KCNJ9G protein-activated inward rectifier potassium channel 3. (385 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1100 aa)
LOC102725943Nuclear factor of activated T-cells, cytoplasmic 2-like. (160 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (252 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1. (221 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
LOC102746012Adenylate cyclase type 3-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (311 aa)
KCNJ14ATP-sensitive inward rectifier potassium channel 14. (432 aa)
CALM3Calmodulin isoform X1; Belongs to the calmodulin family. (149 aa)
LOC102738224LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like. (612 aa)
MEF2CMyocyte-specific enhancer factor 2C-like isoform X2. (473 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (214 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (790 aa)
LOC102729978Beta-actin-like protein 2-like isoform X1. (376 aa)
NPR2Guanylate cyclase. (1047 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (557 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
CACNB1Voltage-dependent L-type calcium channel subunit beta-1 isoform X1. (643 aa)
LOC1027485835'-AMP-activated protein kinase subunit gamma-2-like. (129 aa)
LOC102742813Neuroendocrine secretory protein 55-like. (246 aa)
PRKAG25'-AMP-activated protein kinase subunit gamma-2-like isoform X2. (327 aa)
CACNA2D4Voltage-dependent calcium channel subunit alpha-2/delta-4. (1102 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (1244 aa)
LOC102731583Voltage-dependent calcium channel gamma-3 subunit-like. (315 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
LOC102727336Voltage-dependent calcium channel subunit alpha-2/delta-3-like. (239 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
ROCK2Rho-associated protein kinase 2. (850 aa)
GPR150Probable G-protein coupled receptor 150. (399 aa)
PRKAB15'-AMP-activated protein kinase subunit beta-1. (270 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
EEF2Elongation factor 2. (858 aa)
ERASGTPase ERas. (233 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1983 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2-like. (2701 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (260 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CAMKK2Calcium/calmodulin-dependent protein kinase kinase 2 isoform X1. (578 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
JMJD7jmjC domain-containing protein 7. (316 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (389 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (613 aa)
NPPANatriuretic peptides A. (150 aa)
ACTBActin, cytoplasmic 1. (375 aa)
SRCTyrosine-protein kinase. (536 aa)
CAMK1GCalcium/calmodulin-dependent protein kinase type 1G. (220 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (574 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
LOC102734862Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
LOC102726697Guanine nucleotide-binding protein G(I) subunit alpha-1-like isoform X1. (354 aa)
LOC102738071Calmodulin-like; Belongs to the calmodulin family. (113 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
KCNJ2Inward rectifier potassium channel 2 isoform X1. (427 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
PLA2G4DPhospholipase A2. (817 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4. (430 aa)
PTGS2Prostaglandin G/H synthase 2. (470 aa)
EEF2KEukaryotic elongation factor 2 kinase. (544 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1075 aa)
PPP3R1Calcineurin subunit B type 1 isoform X1. (170 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
CACNB3Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (484 aa)
MYL6Myosin light polypeptide 6 isoform X2. (151 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
RGS2Regulator of G-protein signaling 2. (211 aa)
NRASGTPase NRas. (189 aa)
KRASGTPase KRas isoform X2. (188 aa)
PPP3R2Calcineurin subunit B type 2. (170 aa)
GUCY1A3Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
GUCY1B3Guanylate cyclase soluble subunit beta-1 isoform X1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X1. (1091 aa)
LOC102736922Calmodulin-like; Belongs to the calmodulin family. (223 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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