(40 nodes) Regulation of lipolysis in adipocytes network (Leptonychotes weddellii)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Predicted Interactions

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Your Input:
	LOC102730623	Beta-2 adrenergic receptor-like. (418 aa)
	PRKACA	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
	LOC102731038	Adenylate cyclase type 9-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (564 aa)
	PLIN1	Perilipin-1-like. (766 aa)
	LOC102751021	Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
	FABP12	LOW QUALITY PROTEIN: fatty acid-binding protein 12; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (140 aa)
	PMP2	Myelin P2 protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	FABP4	Fatty acid-binding protein, adipocyte; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	FABP9	Fatty acid-binding protein 9; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	LOC102726446	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
	TSHB	Thyrotropin subunit beta. (138 aa)
	PIK3R3	Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
	ADCY6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
	NPY	Pro-neuropeptide Y. (97 aa)
	PTGS2	Prostaglandin G/H synthase 2. (470 aa)
	LOC102726697	Guanine nucleotide-binding protein G(I) subunit alpha-1-like isoform X1. (354 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
	NPPA	Natriuretic peptides A. (150 aa)
	IRS1	Insulin receptor substrate 1-like isoform X1. (1236 aa)
	PRKACB	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
	GNAI2	Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
	PRKG2	cGMP-dependent protein kinase 2. (553 aa)
	AKT1	Non-specific serine/threonine protein kinase. (518 aa)
	LOC102740198	Prostaglandin G/H synthase 1-like isoform X1. (340 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
	ABHD5	1-acylglycerol-3-phosphate O-acyltransferase ABHD5. (349 aa)
	PRKG1	cGMP-dependent protein kinase 1. (193 aa)
	PTRHD1	Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
	PNPLA2	Patatin-like phospholipase domain-containing protein 2. (486 aa)
	LOC102742813	Neuroendocrine secretory protein 55-like. (246 aa)
	PDE3B	Phosphodiesterase. (1180 aa)
	ADCY9	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (790 aa)
	LOC102746012	Adenylate cyclase type 3-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (311 aa)
	PLA2G16	HRAS-like suppressor 3. (162 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	NPY1R	Neuropeptide Y receptor type 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	LOC102736516	Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
	NPR1	Atrial natriuretic peptide receptor 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (242 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABHD5	PLIN1	A0A2U3YAA9	A0A2U3Z7V7	1-acylglycerol-3-phosphate O-acyltransferase ABHD5.	Perilipin-1-like.	0.905
ABHD5	PNPLA2	A0A2U3YAA9	A0A2U3YCF5	1-acylglycerol-3-phosphate O-acyltransferase ABHD5.	Patatin-like phospholipase domain-containing protein 2.	0.963
ADCY6	ADCY9	A0A2U3XDB9	A0A2U3YLR7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.920
ADCY6	AKT1	A0A2U3XDB9	A0A2U3Y3V3	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase.	0.819
ADCY6	AKT3	A0A2U3XDB9	A0A2U3Y8K7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.866
ADCY6	GNAI2	A0A2U3XDB9	A0A2U3Y188	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I) subunit alpha-2.	0.826
ADCY6	LOC102726697	A0A2U3XDB9	A0A2U3XNG2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(I) subunit alpha-1-like isoform X1.	0.826
ADCY6	LOC102731038	A0A2U3XDB9	A0A2U3Z797	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 9-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.842
ADCY6	LOC102742813	A0A2U3XDB9	A0A2U3YGK0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Neuroendocrine secretory protein 55-like.	0.810
ADCY6	LOC102746012	A0A2U3XDB9	A0A2U3YPK1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase type 3-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.895
ADCY6	NPPA	A0A2U3XDB9	A0A2U3XVT9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Natriuretic peptides A.	0.481
ADCY6	PDE3B	A0A2U3XDB9	A0A2U3YI06	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.864
ADCY6	PRKACA	A0A2U3XDB9	A0A2U3Z6A9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.919
ADCY6	PRKACB	A0A2U3XDB9	A0A2U3XZU0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.928
ADCY6	PTRHD1	A0A2U3XDB9	A0A2U3YCC1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Putative peptidyl-tRNA hydrolase PTRHD1.	0.797
ADCY9	ADCY6	A0A2U3YLR7	A0A2U3XDB9	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.920
ADCY9	AKT1	A0A2U3YLR7	A0A2U3Y3V3	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Non-specific serine/threonine protein kinase.	0.817
ADCY9	AKT3	A0A2U3YLR7	A0A2U3Y8K7	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.813
ADCY9	GNAI2	A0A2U3YLR7	A0A2U3Y188	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanine nucleotide-binding protein G(I) subunit alpha-2.	0.848
ADCY9	LOC102726697	A0A2U3YLR7	A0A2U3XNG2	Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Guanine nucleotide-binding protein G(I) subunit alpha-1-like isoform X1.	0.848