STRINGSTRING
LOC102746012 LOC102746012 ACTG1 ACTG1 CALML4 CALML4 LOC102731038 LOC102731038 LOC102733954 LOC102733954 LOC102732556 LOC102732556 PRKACA PRKACA ARSI ARSI CAMK2A CAMK2A MYLK3 MYLK3 LOC102730715 LOC102730715 KCNJ15 KCNJ15 LOC102735730 LOC102735730 ATP1A1 ATP1A1 ACTL8 ACTL8 PLCB3 PLCB3 ATP1B4 ATP1B4 CALM3 CALM3 ADCY9 ADCY9 LOC102729978 LOC102729978 GAST GAST KCNE2 KCNE2 ITPR3 ITPR3 ATP1A4 ATP1A4 ATP1A2 ATP1A2 KCNJ10 KCNJ10 LRRC69 LRRC69 LOC102742813 LOC102742813 SLC26A7 SLC26A7 OTUD6B OTUD6B ITPR1 ITPR1 SST SST PTRHD1 PTRHD1 ATP1B1 ATP1B1 SLC9A1 SLC9A1 ATP1B2 ATP1B2 ATP4B ATP4B ITPR2 ITPR2 ATP1B3 ATP1B3 GNAI2 GNAI2 SLC9A4 SLC9A4 PRKACB PRKACB KCNQ1 KCNQ1 OTUD6A OTUD6A ACTB ACTB CAMK2G CAMK2G LOC102726697 LOC102726697 CCKBR CCKBR HRH2 HRH2 LOC102738071 LOC102738071 KCNJ2 KCNJ2 KCNJ16 KCNJ16 ATP1A3 ATP1A3 KCNJ1 KCNJ1 SLC4A2 SLC4A2 ADCY6 ADCY6 CFTR CFTR CA2 CA2 LOC102736922 LOC102736922
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102746012Adenylate cyclase type 3-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (311 aa)
ACTG1LOW QUALITY PROTEIN: actin, gamma 1. (411 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like 4. (199 aa)
LOC102731038Adenylate cyclase type 9-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (564 aa)
LOC102733954Calmodulin-like protein 4-like. (119 aa)
LOC102732556Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
ARSIArylsulfatase I. (575 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (476 aa)
MYLK3Myosin light chain kinase 3. (99 aa)
LOC1027307151-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2-like. (231 aa)
KCNJ15ATP-sensitive inward rectifier potassium channel 15 isoform X2. (375 aa)
LOC102735730Sodium/potassium-transporting ATPase subunit alpha-1-like; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (346 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (673 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (366 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1100 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (360 aa)
CALM3Calmodulin isoform X1; Belongs to the calmodulin family. (149 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (790 aa)
LOC102729978Beta-actin-like protein 2-like isoform X1. (376 aa)
GASTGastrin. (104 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2. (123 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (557 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
KCNJ10ATP-sensitive inward rectifier potassium channel 10. (379 aa)
LRRC69Leucine-rich repeat-containing protein 69. (347 aa)
LOC102742813Neuroendocrine secretory protein 55-like. (246 aa)
SLC26A7Anion exchange transporter. (656 aa)
OTUD6BLOW QUALITY PROTEIN: OTU domain-containing protein 6B. (324 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (1244 aa)
SSTSomatostatin. (116 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (817 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2-like. (2701 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
SLC9A4Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (636 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (599 aa)
OTUD6AOTU domain-containing protein 6A. (291 aa)
ACTBActin, cytoplasmic 1. (375 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma. (574 aa)
LOC102726697Guanine nucleotide-binding protein G(I) subunit alpha-1-like isoform X1. (354 aa)
CCKBRGastrin/cholecystokinin type B receptor; Belongs to the G-protein coupled receptor 1 family. (455 aa)
HRH2Histamine H2 receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC102738071Calmodulin-like; Belongs to the calmodulin family. (113 aa)
KCNJ2Inward rectifier potassium channel 2 isoform X1. (427 aa)
KCNJ16Inward rectifier potassium channel 16. (419 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
KCNJ1ATP-sensitive inward rectifier potassium channel 1 isoform X1. (391 aa)
SLC4A2Anion exchange protein. (1237 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1483 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
LOC102736922Calmodulin-like; Belongs to the calmodulin family. (223 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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