(84 nodes) Protein digestion and absorption network (Leptonychotes weddellii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	COL5A1	Collagen alpha-1(V) chain-like. (1676 aa)
	MEP1A	Meprin A subunit. (720 aa)
	SLC8A1	Sodium/calcium exchanger 1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (970 aa)
	CPB1	Carboxypeptidase B. (417 aa)
	CPA3	Mast cell carboxypeptidase A isoform X1. (417 aa)
	COL2A1	Collagen alpha-1(II) chain isoform X1. (1487 aa)
	COL9A1	Collagen alpha-1(IX) chain. (885 aa)
	COL19A1	Collagen alpha-1(XIX) chain. (999 aa)
	SLC7A6	Y+L amino acid transporter 2. (513 aa)
	CTRL	LOW QUALITY PROTEIN: chymotrypsin-like protease CTRL-1; Belongs to the peptidase S1 family. (260 aa)
	LOC102735437	Pepsin A-like; Belongs to the peptidase A1 family. (386 aa)
	COL1A2	Collagen alpha-2(I) chain. (1365 aa)
	C1QTNF2	Complement C1q tumor necrosis factor-related protein 2. (285 aa)
	KCNN4	Intermediate conductance calcium-activated potassium channel protein 4. (427 aa)
	ATP1A3	Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
	COL4A1	Collagen alpha-1(IV) chain. (321 aa)
	SLC36A4	Proton-coupled amino acid transporter 4 isoform X1. (483 aa)
	COL7A1	Collagen alpha-1(VII) chain-like. (532 aa)
	COL26A1	Collagen alpha-1(XXVI) chain. (147 aa)
	COL10A1	Collagen alpha-1(X) chain. (674 aa)
	CPA6	Carboxypeptidase A6. (438 aa)
	SLC8A3	Sodium/calcium exchanger 3 isoform X3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
	XPNPEP2	xaa-Pro aminopeptidase 2-like. (352 aa)
	KCNQ1	Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (599 aa)
	ATP1B3	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
	COL9A2	Collagen alpha-2(IX) chain. (595 aa)
	COL9A3	Collagen alpha-3(IX) chain. (681 aa)
	COL11A2	Collagen alpha-2(XI) chain isoform X1. (1736 aa)
	KCNK5	Potassium channel subfamily K member 5; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (499 aa)
	SLC38A2	Sodium-coupled neutral amino acid transporter 2 isoform X1. (506 aa)
	SLC7A9	B(0,+)-type amino acid transporter 1. (490 aa)
	ATP1B2	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
	SLC7A10	Asc-type amino acid transporter 1. (520 aa)
	KCNJ13	Inward rectifier potassium channel 13 isoform X2. (360 aa)
	ATP1B1	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
	LOC102742903	Collagen alpha-1(I) chain-like. (1116 aa)
	SLC9A5	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (898 aa)
	MFF	Mitochondrial fission factor isoform X2. (342 aa)
	COL4A4	Collagen alpha-4(IV) chain-like. (1589 aa)
	C1QTNF7	Complement C1q tumor necrosis factor-related protein 7 isoform X1. (289 aa)
	OVCH2	Ovochymase-2; Belongs to the peptidase S1 family. (565 aa)
	COL8A1	Collagen alpha-1(VIII) chain isoform X1. (744 aa)
	LOC102747503	Collagen alpha-6(VI) chain-like. (1244 aa)
	VWA2	Von Willebrand factor A domain-containing protein 2. (804 aa)
	LOC102746114	Chymotrypsinogen 2-like; Belongs to the peptidase S1 family. (263 aa)
	ATP1A2	Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
	ATP1A4	Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
	LOC102739415	Cationic trypsin-like; Belongs to the peptidase S1 family. (246 aa)
	LOC102738811	Anionic trypsin-like; Belongs to the peptidase S1 family. (248 aa)
	FXYD2	FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
	COL17A1	Collagen alpha-1(XVII) chain. (1462 aa)
	CELA3B	Chymotrypsin-like elastase family member 3B isoform X2; Belongs to the peptidase S1 family. (270 aa)
	LOC102730795	Amino acid transporter. (272 aa)
	SLC36A2	Proton-coupled amino acid transporter 2. (483 aa)
	LOC102726731	Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (251 aa)
	CTRC	chymotrypsin-C; Belongs to the peptidase S1 family. (268 aa)
	COL6A2	Collagen alpha-2(VI) chain. (1021 aa)
	COL6A1	Collagen alpha-1(VI) chain. (1027 aa)
	ATP1B4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (360 aa)
	LOC102737225	Amino acid transporter. (313 aa)
	SLC3A1	Neutral and basic amino acid transport protein rBAT isoform X1. (681 aa)
	SLC7A7	Y+L amino acid transporter 1. (365 aa)
	LOC102733028	Large neutral amino acids transporter small subunit 2-like. (179 aa)
	CPB2	Carboxypeptidase B2. (423 aa)
	LOC102747715	Sodium-dependent neutral amino acid transporter B(0)AT1-like. (521 aa)
	PRCP	Lysosomal Pro-X carboxypeptidase. (497 aa)
	CELA1	Chymotrypsin-like elastase family member 1; Belongs to the peptidase S1 family. (266 aa)
	COL8A2	Collagen alpha-2(VIII) chain. (699 aa)
	ATP1A1	Sodium/potassium-transporting ATPase subunit alpha. (673 aa)
	LOC102735730	Sodium/potassium-transporting ATPase subunit alpha-1-like; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (346 aa)
	LOC102750303	Collagen alpha-1(I) chain-like. (395 aa)
	LOC102750213	Collagen alpha-1(XXVII) chain-like. (327 aa)
	LOC102729200	Collagen alpha-1(IV) chain-like. (863 aa)
	LOC102729499	Collagen alpha-1(IV) chain-like. (112 aa)
	SLC36A3	Proton-coupled amino acid transporter 3. (336 aa)
	PRSS37	Probable inactive serine protease 37. (235 aa)
	LOC102725778	Collagen alpha-1(XXVII) chain-like. (196 aa)
	LOC102749234	Large neutral amino acids transporter small subunit 2-like. (239 aa)
	KCNE3	Potassium voltage-gated channel subfamily E member 3. (99 aa)
	LOC102731544	Collagen alpha-1(VII) chain-like. (2351 aa)
	LOC102727686	Pepsin F-like; Belongs to the peptidase A1 family. (237 aa)
	LOC102726269	Angiotensin-converting enzyme 2-like. (488 aa)
	LOC102741273	Ovochymase-1-like; Belongs to the peptidase S1 family. (246 aa)
	CTRB1	LOW QUALITY PROTEIN: chymotrypsinogen B1; Belongs to the peptidase S1 family. (285 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP1A1	ATP1A2	A0A2U3YY83	A0A2U3YIE5	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.780
ATP1A1	ATP1A3	A0A2U3YY83	A0A2U3XKQ2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.780
ATP1A1	ATP1A4	A0A2U3YY83	A0A2U3YIE7	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.792
ATP1A1	ATP1B1	A0A2U3YY83	A0A2U3Y7W3	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.999
ATP1A1	ATP1B2	A0A2U3YY83	A0A2U3Y5F4	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.924
ATP1A1	ATP1B3	A0A2U3YY83	A0A2U3Y1H0	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.933
ATP1A1	ATP1B4	A0A2U3YY83	A0A2U3YRB4	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.911
ATP1A1	FXYD2	A0A2U3YY83	A0A2U3YL01	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.999
ATP1A1	LOC102735730	A0A2U3YY83	A0A2U3YYY2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha-1-like; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.951
ATP1A2	ATP1A1	A0A2U3YIE5	A0A2U3YY83	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.780
ATP1A2	ATP1A4	A0A2U3YIE5	A0A2U3YIE7	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.790
ATP1A2	ATP1B1	A0A2U3YIE5	A0A2U3Y7W3	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.942
ATP1A2	ATP1B2	A0A2U3YIE5	A0A2U3Y5F4	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.913
ATP1A2	ATP1B3	A0A2U3YIE5	A0A2U3Y1H0	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.910
ATP1A2	ATP1B4	A0A2U3YIE5	A0A2U3YRB4	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.910
ATP1A2	FXYD2	A0A2U3YIE5	A0A2U3YL01	Sodium/potassium-transporting ATPase subunit alpha.	FXYD domain-containing ion transport regulator; Belongs to the FXYD family.	0.928
ATP1A2	LOC102735730	A0A2U3YIE5	A0A2U3YYY2	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha-1-like; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.	0.781
ATP1A3	ATP1A1	A0A2U3XKQ2	A0A2U3YY83	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.780
ATP1A3	ATP1A4	A0A2U3XKQ2	A0A2U3YIE7	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit alpha.	0.790
ATP1A3	ATP1B1	A0A2U3XKQ2	A0A2U3Y7W3	Sodium/potassium-transporting ATPase subunit alpha.	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family.	0.942