STRINGSTRING
ADCY9 ADCY9 ABCG8 ABCG8 LOC102731038 LOC102731038 LOC102737868 LOC102737868 PRKACA PRKACA LOC102745433 LOC102745433 LOC102738549 LOC102738549 SLC22A8 SLC22A8 LOC102734938 LOC102734938 LOC102735730 LOC102735730 ATP1A1 ATP1A1 UGT1A3 UGT1A3 RXRA RXRA AQP1 AQP1 SLC27A5 SLC27A5 LOC102736937 LOC102736937 LOC102735336 LOC102735336 ATP1B4 ATP1B4 AQP4 AQP4 LOC102746012 LOC102746012 LOC102726731 LOC102726731 FXYD2 FXYD2 LDLR LDLR ATP1A4 ATP1A4 ATP1A2 ATP1A2 LOC102742813 LOC102742813 SLC4A4 SLC4A4 EPHX1 EPHX1 SLC51A SLC51A SLC9A5 SLC9A5 PTRHD1 PTRHD1 ABCC3 ABCC3 ATP1B1 ATP1B1 NR0B2 NR0B2 SLC9A1 SLC9A1 LOC102731486 LOC102731486 ATP1B2 ATP1B2 SLC25A39 SLC25A39 ATP1B3 ATP1B3 PRKACB PRKACB AQP9 AQP9 HMGCR HMGCR SLC51B SLC51B NCEH1 NCEH1 LOC102728008 LOC102728008 ATP1A3 ATP1A3 SLC4A2 SLC4A2 SLC25A40 SLC25A40 ABCB1 ABCB1 LOC102726154 LOC102726154 ADCY6 ADCY6 UGT2A1 UGT2A1 CFTR CFTR SLCO1A2 SLCO1A2 SLCO1B3 SLCO1B3 LOC102729180 LOC102729180 BAAT BAAT CA2 CA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (790 aa)
ABCG8LOW QUALITY PROTEIN: ATP-binding cassette, sub-family G (WHITE), member 8. (519 aa)
LOC102731038Adenylate cyclase type 9-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (564 aa)
LOC102737868Canalicular multispecific organic anion transporter 1-like. (280 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC102745433Sodium/bile acid cotransporter-like. (198 aa)
LOC102738549Ileal sodium/bile acid cotransporter-like. (320 aa)
SLC22A8Solute carrier family 22 member 8. (543 aa)
LOC102734938Secretin-like. (108 aa)
LOC102735730Sodium/potassium-transporting ATPase subunit alpha-1-like; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (346 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (673 aa)
UGT1A3UDP-glucuronosyltransferase 1-3. (301 aa)
RXRARetinoic acid receptor RXR-alpha. (439 aa)
AQP1Aquaporin-1 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SLC27A5Bile acyl-CoA synthetase. (687 aa)
LOC102736937Low affinity sodium-glucose cotransporter-like; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (359 aa)
LOC102735336Sodium/glucose cotransporter 1-like isoform X3; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (664 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (360 aa)
AQP4Aquaporin-4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (301 aa)
LOC102746012Adenylate cyclase type 3-like; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (311 aa)
LOC102726731Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (251 aa)
FXYD2FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (66 aa)
LDLRLow-density lipoprotein receptor. (861 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1030 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
LOC102742813Neuroendocrine secretory protein 55-like. (246 aa)
SLC4A4Anion exchange protein. (1081 aa)
EPHX1Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (454 aa)
SLC51AOrganic solute transporter subunit alpha. (363 aa)
SLC9A5Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (898 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (140 aa)
ABCC3Canalicular multispecific organic anion transporter 2. (1523 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (279 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (817 aa)
LOC102731486Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (501 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
SLC25A39Solute carrier family 25 member 39 isoform X1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (359 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (280 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
AQP9Aquaporin-9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
HMGCR3-hydroxy-3-methylglutaryl coenzyme A reductase. (887 aa)
SLC51BOrganic solute transporter subunit beta. (128 aa)
NCEH1Neutral cholesterol ester hydrolase 1 isoform X2. (408 aa)
LOC102728008UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (527 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (1027 aa)
SLC4A2Anion exchange protein. (1237 aa)
SLC25A40Solute carrier family 25 member 40; Belongs to the mitochondrial carrier (TC 2.A.29) family. (318 aa)
ABCB1Multidrug resistance protein 1. (1280 aa)
LOC102726154UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
ADCY6Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
UGT2A1UDP-glucuronosyltransferase 2A3-like isoform X1; Belongs to the UDP-glycosyltransferase family. (694 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1483 aa)
SLCO1A2Solute carrier organic anion transporter family member. (670 aa)
SLCO1B3Solute carrier organic anion transporter family member. (689 aa)
LOC102729180Acyl-coenzyme A amino acid N-acyltransferase 2-like. (419 aa)
BAATLOW QUALITY PROTEIN: bile acid-CoA:amino acid N-acyltransferase. (421 aa)
CA2Carbonic anhydrase 2; Belongs to the alpha-carbonic anhydrase family. (260 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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