STRINGSTRING
LOC102726697 LOC102726697 CAMKK2 CAMKK2 PPP1CC PPP1CC GNG5 GNG5 PRKACB PRKACB CEP152 CEP152 LOC102738888 LOC102738888 SHC4 SHC4 LOC102738582 LOC102738582 LOC102738290 LOC102738290 LOC102737083 LOC102737083 LOC102732990 LOC102732990 MAOA MAOA MAOB MAOB LOC102728431 LOC102728431 LOC102750817 LOC102750817 LOC102746084 LOC102746084 LOC102741581 LOC102741581 LOC102739804 LOC102739804 LOC102747282 LOC102747282 LOC102744317 LOC102744317 LOC102744019 LOC102744019 LOC102743711 LOC102743711 LOC102742187 LOC102742187 LOC102744630 LOC102744630 SHC1 SHC1 GRIN2A GRIN2A HDAC1 HDAC1 LOC102750808 LOC102750808 GNB2 GNB2 GNG10 GNG10 CREB1 CREB1 GNB5 GNB5 GRIN1 GRIN1 GNG11 GNG11 GNGT1 GNGT1 DRD1 DRD1 LOC102738071 LOC102738071 LOC102731039 LOC102731039 HAT1 HAT1 GNG3 GNG3 ATF4 ATF4 NPY NPY HDAC9 HDAC9 CSDE1 CSDE1 NRAS NRAS KRAS KRAS GRIN3A GRIN3A ZC2HC1A ZC2HC1A PKIA PKIA LOC102736922 LOC102736922 CALML4 CALML4 LOC102733954 LOC102733954 PRKACA PRKACA LOC102743898 LOC102743898 LOC102746549 LOC102746549 HDAC3 HDAC3 LOC102748147 LOC102748147 PPP1R1B PPP1R1B ADORA2A ADORA2A GNB4 GNB4 LOC102746847 LOC102746847 LOC102745013 LOC102745013 LOC102743792 LOC102743792 LOC102745317 LOC102745317 LOC102744100 LOC102744100 CAMK4 CAMK4 TH TH LOC102730819 LOC102730819 PPP1CA PPP1CA LOC102730207 LOC102730207 LOC102725568 LOC102725568 SLC29A2 SLC29A2 LOC102726670 LOC102726670 LOC102750685 LOC102750685 LOC102750992 LOC102750992 LOC102747249 LOC102747249 CRH CRH SLC29A1 SLC29A1 CREB3L1 CREB3L1 GNAO1 GNAO1 LOC102748609 LOC102748609 LOC102732330 LOC102732330 GNG2 GNG2 PDYN PDYN CAMKK1 CAMKK1 GNG4 GNG4 LOC102736718 LOC102736718 LOC102739131 LOC102739131 GRIN2D GRIN2D SLC18A1 SLC18A1 CALM3 CALM3 LOC102731297 LOC102731297 GNG8 GNG8 LOC102729768 LOC102729768 MAPK1 MAPK1 HDAC2 HDAC2 LOC102742813 LOC102742813 ATF2 ATF2 PPP1CB PPP1CB GNGT2 GNGT2 HDAC4 HDAC4 HDAC8 HDAC8 RAF1 RAF1 LOC102745475 LOC102745475 LOC102741496 LOC102741496 NTRK2 NTRK2 HDAC7 HDAC7 GNG13 GNG13 LOC102726804 LOC102726804 HDAC5 HDAC5 CREB3L3 CREB3L3 FOSB FOSB ATF6B ATF6B ERAS ERAS GNB3 GNB3 LOC102738587 LOC102738587 GNAI2 GNAI2
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102726697Guanine nucleotide-binding protein G(I) subunit alpha-1-like isoform X1. (354 aa)
CAMKK2Calcium/calmodulin-dependent protein kinase kinase 2 isoform X1. (578 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
CEP152Centrosomal protein of 152 kDa isoform X1. (1723 aa)
LOC102738888Histone H1.5-like. (226 aa)
SHC4SHC-transforming protein 4. (630 aa)
LOC102738582Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC102738290Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102737083Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102732990Histone H2A; Belongs to the histone H2A family. (140 aa)
MAOAAmine oxidase. (527 aa)
MAOBAmine oxidase. (504 aa)
LOC102728431Histone H2B; Belongs to the histone H2B family. (119 aa)
LOC102750817Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102746084Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC102741581Histone H1.1-like. (215 aa)
LOC102739804Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102747282Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC102744317Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102744019Histone H1.4-like. (219 aa)
LOC102743711Histone H1t-like. (207 aa)
LOC102742187Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102744630D(2) dopamine receptor-like. (298 aa)
SHC1SHC-transforming protein 1 isoform X2. (583 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1308 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
LOC102750808Histone H2A; Belongs to the histone H2A family. (129 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1. (340 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (345 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
LOC102738071Calmodulin-like; Belongs to the calmodulin family. (113 aa)
LOC102731039Histone H3.3-like. (128 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
NPYPro-neuropeptide Y. (97 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1065 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
NRASGTPase NRas. (189 aa)
KRASGTPase KRas isoform X2. (188 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A. (1115 aa)
ZC2HC1AZinc finger C2HC domain-containing protein 1A. (265 aa)
PKIAcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
LOC102736922Calmodulin-like; Belongs to the calmodulin family. (223 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like 4. (199 aa)
LOC102733954Calmodulin-like protein 4-like. (119 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC102743898Histone H2B type W-T-like; Belongs to the histone H2B family. (174 aa)
LOC102746549Glutamate receptor ionotropic, NMDA 2C-like. (348 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
LOC102748147Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PPP1R1BProtein phosphatase 1 regulatory subunit 1B. (205 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
LOC102746847Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102745013Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102743792Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC102745317Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102744100Histone H2A; Belongs to the histone H2A family. (130 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV. (360 aa)
THTyrosine 3-monooxygenase. (307 aa)
LOC102730819Histone H3; Belongs to the histone H3 family. (136 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
LOC102730207Histone H2A; Belongs to the histone H2A family. (143 aa)
LOC102725568Histone H2B; Belongs to the histone H2B family. (127 aa)
SLC29A2Equilibrative nucleoside transporter 2. (456 aa)
LOC102726670Histone H2A; Belongs to the histone H2A family. (131 aa)
LOC102750685Histone H2A; Belongs to the histone H2A family. (131 aa)
LOC102750992Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC102747249Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (271 aa)
CRHCorticoliberin. (196 aa)
SLC29A1Equilibrative nucleoside transporter 1. (456 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (474 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (311 aa)
LOC102748609Sodium-dependent dopamine transporter-like. (364 aa)
LOC102732330Histone H3; Belongs to the histone H3 family. (136 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
PDYNproenkephalin-B. (256 aa)
CAMKK1Calcium/calmodulin-dependent protein kinase kinase 1; Belongs to the protein kinase superfamily. (460 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC102736718Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC102739131D(2) dopamine receptor-like; Belongs to the G-protein coupled receptor 1 family. (198 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (840 aa)
SLC18A1Chromaffin granule amine transporter isoform X1. (525 aa)
CALM3Calmodulin isoform X1; Belongs to the calmodulin family. (149 aa)
LOC102731297Histone H2A; Belongs to the histone H2A family. (117 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC102729768Huntingtin-interacting protein M. (113 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
LOC102742813Neuroendocrine secretory protein 55-like. (246 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
HDAC4Histone deacetylase 4-like. (667 aa)
HDAC8Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (415 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LOC102745475Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like isoform X1. (340 aa)
LOC102741496BDNF/NT-3 growth factors receptor-like. (97 aa)
NTRK2BDNF/NT-3 growth factors receptor-like. (420 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (928 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
LOC102726804Histone H2B; Belongs to the histone H2B family. (126 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1116 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (466 aa)
FOSBProtein fosB isoform X1. (335 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta. (623 aa)
ERASGTPase ERas. (233 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
LOC102738587Histone H2B subacrosomal variant-like; Belongs to the histone H2B family. (122 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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