STRINGSTRING
LOC102736922 LOC102736922 PKIA PKIA ZC2HC1A ZC2HC1A GRIN3A GRIN3A KRAS KRAS NRAS NRAS CSDE1 CSDE1 HDAC9 HDAC9 NPY NPY ATF4 ATF4 GNG3 GNG3 HAT1 HAT1 LOC102731039 LOC102731039 LOC102738071 LOC102738071 DRD1 DRD1 GNGT1 GNGT1 GNG11 GNG11 LOC102726697 LOC102726697 GNB5 GNB5 CREB1 CREB1 GNG10 GNG10 GNB2 GNB2 LOC102750808 LOC102750808 HDAC1 HDAC1 GRIN2A GRIN2A SHC1 SHC1 LOC102744630 LOC102744630 LOC102742187 LOC102742187 LOC102743711 LOC102743711 LOC102744019 LOC102744019 LOC102744317 LOC102744317 LOC102747282 LOC102747282 LOC102739804 LOC102739804 LOC102741581 LOC102741581 LOC102746084 LOC102746084 LOC102750817 LOC102750817 LOC102728431 LOC102728431 MAOB MAOB MAOA MAOA LOC102732990 LOC102732990 LOC102737083 LOC102737083 LOC102738290 LOC102738290 LOC102738582 LOC102738582 SHC4 SHC4 LOC102738888 LOC102738888 CEP152 CEP152 PRKACB PRKACB GNG5 GNG5 PPP1CC PPP1CC CAMKK2 CAMKK2 GRIN1 GRIN1 GNAI2 GNAI2 LOC102738587 LOC102738587 GNB3 GNB3 ERAS ERAS ATF6B ATF6B FOSB FOSB CREB3L3 CREB3L3 HDAC5 HDAC5 LOC102726804 LOC102726804 GNG13 GNG13 HDAC7 HDAC7 NTRK2 NTRK2 LOC102741496 LOC102741496 LOC102745475 LOC102745475 RAF1 RAF1 HDAC8 HDAC8 HDAC4 HDAC4 GNGT2 GNGT2 PPP1CB PPP1CB ATF2 ATF2 LOC102742813 LOC102742813 HDAC2 HDAC2 MAPK1 MAPK1 LOC102729768 LOC102729768 GNG8 GNG8 LOC102731297 LOC102731297 CALM3 CALM3 SLC18A1 SLC18A1 GRIN2D GRIN2D LOC102739131 LOC102739131 LOC102736718 LOC102736718 GNG4 GNG4 CAMKK1 CAMKK1 PDYN PDYN GNG2 GNG2 LOC102732330 LOC102732330 LOC102748609 LOC102748609 GNAO1 GNAO1 CREB3L1 CREB3L1 SLC29A1 SLC29A1 CRH CRH LOC102747249 LOC102747249 LOC102750992 LOC102750992 LOC102750685 LOC102750685 LOC102726670 LOC102726670 SLC29A2 SLC29A2 LOC102725568 LOC102725568 LOC102730207 LOC102730207 PPP1CA PPP1CA LOC102730819 LOC102730819 TH TH CAMK4 CAMK4 LOC102744100 LOC102744100 LOC102745317 LOC102745317 LOC102743792 LOC102743792 LOC102745013 LOC102745013 LOC102746847 LOC102746847 GNB4 GNB4 ADORA2A ADORA2A PPP1R1B PPP1R1B LOC102748147 LOC102748147 HDAC3 HDAC3 LOC102746549 LOC102746549 LOC102743898 LOC102743898 PRKACA PRKACA LOC102733954 LOC102733954 CALML4 CALML4
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102736922Calmodulin-like; Belongs to the calmodulin family. (223 aa)
PKIAcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
ZC2HC1AZinc finger C2HC domain-containing protein 1A. (265 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A. (1115 aa)
KRASGTPase KRas isoform X2. (188 aa)
NRASGTPase NRas. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1065 aa)
NPYPro-neuropeptide Y. (97 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
LOC102731039Histone H3.3-like. (128 aa)
LOC102738071Calmodulin-like; Belongs to the calmodulin family. (113 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (446 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC102726697Guanine nucleotide-binding protein G(I) subunit alpha-1-like isoform X1. (354 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (345 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1. (340 aa)
LOC102750808Histone H2A; Belongs to the histone H2A family. (129 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1308 aa)
SHC1SHC-transforming protein 1 isoform X2. (583 aa)
LOC102744630D(2) dopamine receptor-like. (298 aa)
LOC102742187Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102743711Histone H1t-like. (207 aa)
LOC102744019Histone H1.4-like. (219 aa)
LOC102744317Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102747282Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC102739804Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102741581Histone H1.1-like. (215 aa)
LOC102746084Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC102750817Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102728431Histone H2B; Belongs to the histone H2B family. (119 aa)
MAOBAmine oxidase. (504 aa)
MAOAAmine oxidase. (527 aa)
LOC102732990Histone H2A; Belongs to the histone H2A family. (140 aa)
LOC102737083Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102738290Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102738582Histone H2A; Belongs to the histone H2A family. (130 aa)
SHC4SHC-transforming protein 4. (630 aa)
LOC102738888Histone H1.5-like. (226 aa)
CEP152Centrosomal protein of 152 kDa isoform X1. (1723 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
CAMKK2Calcium/calmodulin-dependent protein kinase kinase 2 isoform X1. (578 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (943 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (303 aa)
LOC102738587Histone H2B subacrosomal variant-like; Belongs to the histone H2B family. (122 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
ERASGTPase ERas. (233 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta. (623 aa)
FOSBProtein fosB isoform X1. (335 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (466 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1116 aa)
LOC102726804Histone H2B; Belongs to the histone H2B family. (126 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (928 aa)
NTRK2BDNF/NT-3 growth factors receptor-like. (420 aa)
LOC102741496BDNF/NT-3 growth factors receptor-like. (97 aa)
LOC102745475Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like isoform X1. (340 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
HDAC8Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (415 aa)
HDAC4Histone deacetylase 4-like. (667 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X2. (505 aa)
LOC102742813Neuroendocrine secretory protein 55-like. (246 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
LOC102729768Huntingtin-interacting protein M. (113 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC102731297Histone H2A; Belongs to the histone H2A family. (117 aa)
CALM3Calmodulin isoform X1; Belongs to the calmodulin family. (149 aa)
SLC18A1Chromaffin granule amine transporter isoform X1. (525 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (840 aa)
LOC102739131D(2) dopamine receptor-like; Belongs to the G-protein coupled receptor 1 family. (198 aa)
LOC102736718Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CAMKK1Calcium/calmodulin-dependent protein kinase kinase 1; Belongs to the protein kinase superfamily. (460 aa)
PDYNproenkephalin-B. (256 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
LOC102732330Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102748609Sodium-dependent dopamine transporter-like. (364 aa)
GNAO1Guanine nucleotide-binding protein G(O) subunit alpha. (311 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (474 aa)
SLC29A1Equilibrative nucleoside transporter 1. (456 aa)
CRHCorticoliberin. (196 aa)
LOC102747249Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (271 aa)
LOC102750992Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC102750685Histone H2A; Belongs to the histone H2A family. (131 aa)
LOC102726670Histone H2A; Belongs to the histone H2A family. (131 aa)
SLC29A2Equilibrative nucleoside transporter 2. (456 aa)
LOC102725568Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC102730207Histone H2A; Belongs to the histone H2A family. (143 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
LOC102730819Histone H3; Belongs to the histone H3 family. (136 aa)
THTyrosine 3-monooxygenase. (307 aa)
CAMK4Calcium/calmodulin-dependent protein kinase type IV. (360 aa)
LOC102744100Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC102745317Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102743792Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC102745013Histone H3; Belongs to the histone H3 family. (136 aa)
LOC102746847Histone H2B; Belongs to the histone H2B family. (126 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
PPP1R1BProtein phosphatase 1 regulatory subunit 1B. (205 aa)
LOC102748147Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
HDAC3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)
LOC102746549Glutamate receptor ionotropic, NMDA 2C-like. (348 aa)
LOC102743898Histone H2B type W-T-like; Belongs to the histone H2B family. (174 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC102733954Calmodulin-like protein 4-like. (119 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like 4. (199 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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