STRINGSTRING
GAB1 GAB1 LOC102729316 LOC102729316 SHC1 SHC1 LOC102737768 LOC102737768 LOC102750306 LOC102750306 LOC102742250 LOC102742250 SEPT2 SEPT2 LOC102727164 LOC102727164 LOC102729189 LOC102729189 ACTL8 ACTL8 LOC102750394 LOC102750394 LOC102736516 LOC102736516 RHOG RHOG PIK3CA PIK3CA PIK3CD PIK3CD CLTCL1 CLTCL1 SLC25A1 SLC25A1 CRKL CRKL CDC42 CDC42 LOC102729978 LOC102729978 ARPC5L ARPC5L GOLGA2 GOLGA2 DNM1 DNM1 LOC102743218 LOC102743218 CLTA CLTA SEPT11 SEPT11 LOC102729514 LOC102729514 LOC102750230 LOC102750230 LOC102735070 LOC102735070 LOC102726881 LOC102726881 FN1 FN1 CAV3 CAV3 SHC4 SHC4 LOC102751021 LOC102751021 LOC102741966 LOC102741966 CAV1 CAV1 ARPC5 ARPC5 PIK3R3 PIK3R3 CAV2 CAV2 ACTG1 ACTG1 SEPT8 SEPT8 ACTB ACTB SRC SRC VCL VCL ILK ILK LOC102731357 LOC102731357 LOC102740357 LOC102740357 LOC102731397 LOC102731397 ITGA5 ITGA5 LPXN LPXN CTTN CTTN SEPT6 SEPT6 CEP152 CEP152 ELMO3 ELMO3 CLTC CLTC SEPT3 SEPT3 LOC102747200 LOC102747200 CTNNA1 CTNNA1 ELMO2 ELMO2 CBL CBL SEPT1 SEPT1 ITGB1 ITGB1 DNM3 DNM3 LOC102745156 LOC102745156 ARPC3 ARPC3 LOC102749407 LOC102749407 CD2AP CD2AP WASL WASL LOC102726446 LOC102726446 LOC102738933 LOC102738933 CDH1 CDH1 WASF1 WASF1 LOC102727172 LOC102727172 ARPC1B ARPC1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAB1GRB2-associated-binding protein 1 isoform X1. (724 aa)
LOC102729316Coiled-coil domain-containing protein 70-like. (233 aa)
SHC1SHC-transforming protein 1 isoform X2. (583 aa)
LOC102737768Actin-related protein 2/3 complex subunit 1A-like. (101 aa)
LOC102750306Golgin subfamily A member 2-like. (84 aa)
LOC102742250Septin-10-like; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (454 aa)
SEPT2Septin-2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (361 aa)
LOC102727164Rho-related GTP-binding protein RhoG-like. (191 aa)
LOC102729189Dedicator of cytokinesis protein 5-like. (273 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (366 aa)
LOC102750394Dedicator of cytokinesis protein 1-like. (237 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
RHOGRho-related GTP-binding protein RhoG. (223 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
CLTCL1Clathrin heavy chain 2. (825 aa)
SLC25A1Tricarboxylate transport protein, mitochondrial; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)
CRKLCrk-like protein. (303 aa)
CDC42Cell division control protein 42 homolog. (160 aa)
LOC102729978Beta-actin-like protein 2-like isoform X1. (376 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
GOLGA2Golgin subfamily A member 2-like. (942 aa)
DNM1Dynamin-1 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)
LOC102743218Protein C9orf69 homolog. (162 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (171 aa)
SEPT11Septin-11 isoform X2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (374 aa)
LOC102729514Septin-9-like. (267 aa)
LOC102750230Septin-12-like; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (128 aa)
LOC102735070Dedicator of cytokinesis protein 5-like; Belongs to the DOCK family. (294 aa)
LOC102726881Breast cancer anti-estrogen resistance protein 1-like. (695 aa)
FN1Fibronectin isoform X1. (2476 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
SHC4SHC-transforming protein 4. (630 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102741966Septin-9-like; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (141 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
ACTG1LOW QUALITY PROTEIN: actin, gamma 1. (411 aa)
SEPT8Septin-8 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (382 aa)
ACTBActin, cytoplasmic 1. (375 aa)
SRCTyrosine-protein kinase. (536 aa)
VCLVinculin isoform X1. (1134 aa)
ILKIntegrin-linked protein kinase isoform X1. (452 aa)
LOC102731357Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
LOC102740357Cell division control protein 42 homolog. (191 aa)
LOC102731397Septin-9-like; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (245 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1054 aa)
LPXNLeupaxin; Belongs to the paxillin family. (386 aa)
CTTNSrc substrate cortactin. (545 aa)
SEPT6Septin-6 isoform X2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (429 aa)
CEP152Centrosomal protein of 152 kDa isoform X1. (1723 aa)
ELMO3Engulfment and cell motility protein 3. (720 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
SEPT3Neuronal-specific septin-3 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
LOC102747200Septin-11-like. (97 aa)
CTNNA1Catenin alpha-1 isoform X1. (906 aa)
ELMO2Engulfment and cell motility protein 2. (377 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
SEPT1Septin-1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (367 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
DNM3Dynamin-3 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (865 aa)
LOC102745156Catenin beta-1-like isoform X1. (216 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
LOC102749407Catenin alpha-2-like. (304 aa)
CD2APCD2-associated protein. (639 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (487 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
LOC102738933Catenin alpha-3-like. (530 aa)
CDH1Cadherin-1; Cadherins are calcium-dependent cell adhesion proteins. (879 aa)
WASF1wiskott-Aldrich syndrome protein family member 1 isoform X1. (559 aa)
LOC102727172Engulfment and cell motility protein 1-like. (247 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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