STRINGSTRING
DVL2 DVL2 TADA3 TADA3 CCNE1 CCNE1 ATP6V1A ATP6V1A ATP6V0C ATP6V0C LOC102730047 LOC102730047 IKBKG IKBKG ATP6AP1 ATP6AP1 LOC102747879 LOC102747879 MAML1 MAML1 AKT3 AKT3 CDK4 CDK4 FZD10 FZD10 PPP2R5C PPP2R5C MDM2 MDM2 RAF1 RAF1 RPS6KB1 RPS6KB1 LOC102744445 LOC102744445 LOC102749586 LOC102749586 RB1 RB1 LOC102742903 LOC102742903 CHAD CHAD LOC102743414 LOC102743414 CSNK1A1 CSNK1A1 MX1 MX1 ITGA4 ITGA4 STAT2 STAT2 LOC102739404 LOC102739404 ITGA9 ITGA9 WNT5A WNT5A CHUK CHUK ATP6V0D1 ATP6V0D1 TRADD TRADD ITGB7 ITGB7 MFF MFF COL4A4 COL4A4 LOC102748381 LOC102748381 THBS1 THBS1 LOC102734089 LOC102734089 LOC102734199 LOC102734199 GSK3B GSK3B MFNG MFNG WNT5B WNT5B LOC102729256 LOC102729256 LOC102742813 LOC102742813 WNT10A WNT10A WNT6 WNT6 LOC102747503 LOC102747503 LOC102726023 LOC102726023 RFNG RFNG PPP2R2C PPP2R2C VWA2 VWA2 WNT11 WNT11 HDAC2 HDAC2 WNT3A WNT3A MAPK1 MAPK1 WNT9B WNT9B WNT3 WNT3 IKBKB IKBKB FZD9 FZD9 ATM ATM PPP2R5A PPP2R5A PARP8 PARP8 LOC102730789 LOC102730789 WNT4 WNT4 CDC42 CDC42 ATP6V1C1 ATP6V1C1 TBP TBP CCND1 CCND1 CASP3 CASP3 LOC102731813 LOC102731813 LOC102741220 LOC102741220 PPP2R5E PPP2R5E ATP6V1B2 ATP6V1B2 LOC102730286 LOC102730286 PIK3CD PIK3CD ATP6V1H ATP6V1H COL6A2 COL6A2 LOC102726140 LOC102726140 HEYL HEYL PIK3CA PIK3CA COL6A1 COL6A1 HES3 HES3 TYK2 TYK2 LOC102738827 LOC102738827 CREBBP CREBBP FZD4 FZD4 TBPL1 TBPL1 LOC102736516 LOC102736516 LOC102732031 LOC102732031 CREB3L1 CREB3L1 NCOA7 NCOA7 LOC102735127 LOC102735127 LOC102739552 LOC102739552 NOTCH2 NOTCH2 COMP COMP LOC102750211 LOC102750211 LOC102736228 LOC102736228 LOC102747537 LOC102747537 LOC102732238 LOC102732238 PPP2R3B PPP2R3B PARD6A PARD6A LOC102750303 LOC102750303 CRB3 CRB3 LOC102745732 LOC102745732 IFNAR1 IFNAR1 ATP6V0B ATP6V0B WNT2B WNT2B LOC102729200 LOC102729200 LOC102729499 LOC102729499 CASP8 CASP8 HEY2 HEY2 LOC102740057 LOC102740057 LOC102745316 LOC102745316 LAMB2 LAMB2 LAMA5 LAMA5 LOC102729504 LOC102729504 LOC102736544 LOC102736544 LOC102750316 LOC102750316 LOC102730629 LOC102730629 FOXO1 FOXO1 CDKN1A CDKN1A RPS6KB2 RPS6KB2 LOC102734846 LOC102734846 LOC102730118 LOC102730118 PRKACA PRKACA LOC102738667 LOC102738667 LOC102726484 LOC102726484 LOC102749847 LOC102749847 LOC102729516 LOC102729516 LOC102726878 LOC102726878 LLGL2 LLGL2 WNT10B WNT10B LOC102727373 LOC102727373 COL1A2 COL1A2 ATP6V0E2 ATP6V0E2 LOC102739066 LOC102739066 PTGS2 PTGS2 LOC102740357 LOC102740357 PPP2CB PPP2CB VTN VTN EP300 EP300 LFNG LFNG CCNE2 CCNE2 MAP2K1 MAP2K1 UBE3A UBE3A ATP6V1G3 ATP6V1G3 COL9A1 COL9A1 COL2A1 COL2A1 RHEBL1 RHEBL1 WNT1 WNT1 CCND3 CCND3 LAMC1 LAMC1 PIK3R3 PIK3R3 CDK2 CDK2 ITGA7 ITGA7 ITGA5 ITGA5 CSDE1 CSDE1 LPXN LPXN NRAS NRAS LRRC1 LRRC1 LOC102746429 LOC102746429 ATP6V1B1 ATP6V1B1 WNT16 WNT16 LOC102726446 LOC102726446 PPP2R3A PPP2R3A KRAS KRAS ATP6V0D2 ATP6V0D2 LOC102746125 LOC102746125 SPP1 SPP1 IBSP IBSP LOC102745703 LOC102745703 PARD6B PARD6B AXIN1 AXIN1 ITGA10 ITGA10 DVL1 DVL1 PRKCZ PRKCZ ISG15 ISG15 NFKB1 NFKB1 COL4A1 COL4A1 LOC102737670 LOC102737670 PTEN PTEN LOC102747757 LOC102747757 LOC102747471 LOC102747471 IFNB1 IFNB1 CDKN1B CDKN1B PTGER4 PTGER4 CREB1 CREB1 FZD5 FZD5 RBL1 RBL1 HDAC1 HDAC1 DLG2 DLG2 ITGB3 ITGB3 FZD7 FZD7 MPP5 MPP5 LOC102731565 LOC102731565 IRF1 IRF1 ATP6V1D ATP6V1D LOC102751021 LOC102751021 LOC102730129 LOC102730129 IFNA14 IFNA14 THBS3 THBS3 LOC102745146 LOC102745146 FN1 FN1 FZD3 FZD3 RBPJL RBPJL MTOR MTOR FZD2 FZD2 VWF VWF GPSM3 GPSM3 NOTCH4 NOTCH4 PRKCI PRKCI TBPL2 TBPL2 LOC102743194 LOC102743194 PPP2R5D PPP2R5D PPP2R2A PPP2R2A FADD FADD PRKACB PRKACB JAG1 JAG1 WNT8A WNT8A LOC102745156 LOC102745156 DLG3 DLG3 EIF2AK2 EIF2AK2 COL9A2 COL9A2 FASLG FASLG ITGB1 ITGB1 OASL OASL CHD4 CHD4 TNFRSF1A TNFRSF1A COL9A3 COL9A3 BAK1 BAK1 DVL3 DVL3 ALOXE3 ALOXE3 AKT1 AKT1 ERAS ERAS TNF TNF TUBG1 TUBG1 TUBG2 TUBG2 LOC102746195 LOC102746195 IRF9 IRF9 CREB3L3 CREB3L3 LOC102749767 LOC102749767 MAP2K2 MAP2K2 TCF7L1 TCF7L1 TP53 TP53 LOC102727975 LOC102727975
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X1. (734 aa)
TADA3Transcriptional adapter 3 isoform X1. (432 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa)
ATP6V1AV-type proton ATPase catalytic subunit A. (394 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
LOC102730047Tuberin-like. (353 aa)
IKBKGNF-kappa-B essential modulator isoform X2. (419 aa)
ATP6AP1V-type proton ATPase subunit S1. (464 aa)
LOC102747879V-type proton ATPase subunit e 1-like. (81 aa)
MAML1Mastermind-like protein 1. (948 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (487 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
RPS6KB1Non-specific serine/threonine protein kinase. (445 aa)
LOC102744445Integrin beta; Belongs to the integrin beta chain family. (197 aa)
LOC102749586V-type proton ATPase subunit E 2-like. (226 aa)
RB1Retinoblastoma-associated protein. (846 aa)
LOC102742903Collagen alpha-1(I) chain-like. (1116 aa)
CHADChondroadherin isoform X1. (359 aa)
LOC102743414Thrombospondin-2-like. (463 aa)
CSNK1A1Casein kinase I isoform alpha; Belongs to the protein kinase superfamily. (227 aa)
MX1Interferon-induced GTP-binding protein Mx1. (291 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1033 aa)
STAT2Signal transducer and activator of transcription. (854 aa)
LOC102739404Integrin alpha-9-like. (152 aa)
ITGA9Integrin alpha-9-like. (470 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
ATP6V0D1V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (312 aa)
ITGB7Integrin beta; Belongs to the integrin beta chain family. (763 aa)
MFFMitochondrial fission factor isoform X2. (342 aa)
COL4A4Collagen alpha-4(IV) chain-like. (1589 aa)
LOC102748381Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like. (618 aa)
THBS1Thrombospondin-1 isoform X1. (1170 aa)
LOC102734089Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1-like. (154 aa)
LOC102734199V-type proton ATPase subunit E 1-like. (206 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
LOC102729256TNF receptor-associated factor 3-like. (283 aa)
LOC102742813Neuroendocrine secretory protein 55-like. (246 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (261 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (362 aa)
LOC102747503Collagen alpha-6(VI) chain-like. (1244 aa)
LOC102726023Transcriptional repressor NF-X1-like. (346 aa)
RFNGbeta-1,3-N-acetylglucosaminyltransferase radical fringe. (286 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform. (231 aa)
VWA2Von Willebrand factor A domain-containing protein 2. (804 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
HDAC2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (488 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (218 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
FZD9Frizzled-9; Belongs to the G-protein coupled receptor Fz/Smo family. (407 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3054 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
PARP8Poly [ADP-ribose] polymerase. (656 aa)
LOC102730789TNF receptor-associated factor 3-like. (295 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
CDC42Cell division control protein 42 homolog. (160 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
TBPTATA-box-binding protein. (322 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (214 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (302 aa)
LOC102731813Frizzled-6-like; Belongs to the G-protein coupled receptor Fz/Smo family. (400 aa)
LOC102741220Integrin alpha-9-like. (114 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
LOC102730286Interferon-induced GTP-binding protein Mx1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (349 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (470 aa)
COL6A2Collagen alpha-2(VI) chain. (1021 aa)
LOC102726140Frizzled-1-like; Belongs to the G-protein coupled receptor Fz/Smo family. (647 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein. (328 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
COL6A1Collagen alpha-1(VI) chain. (1027 aa)
HES3Transcription factor HES-3. (178 aa)
TYK2Non-receptor tyrosine-protein kinase TYK2-like. (767 aa)
LOC102738827Unconventional myosin-XV-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2226 aa)
CREBBPCREB-binding protein-like. (1411 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
LOC102732031Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like. (407 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (474 aa)
NCOA7Nuclear receptor coactivator 7-like isoform X1. (943 aa)
LOC10273512726S protease regulatory subunit 4-like isoform X1; Belongs to the AAA ATPase family. (440 aa)
LOC102739552Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
NOTCH2Neurogenic locus notch homolog protein 2. (1238 aa)
COMPCartilage oligomeric matrix protein. (728 aa)
LOC102750211Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (154 aa)
LOC102736228Partitioning defective 3 homolog. (214 aa)
LOC102747537Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (549 aa)
LOC102732238Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (265 aa)
PPP2R3BSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (596 aa)
PARD6APartitioning defective 6 homolog alpha isoform X1. (346 aa)
LOC102750303Collagen alpha-1(I) chain-like. (395 aa)
CRB3Protein crumbs homolog 3. (123 aa)
LOC102745732Leucine-rich repeat-containing protein 1-like. (92 aa)
IFNAR1Interferon alpha/beta receptor 1. (560 aa)
ATP6V0BV-type proton ATPase 21 kDa proteolipid subunit isoform X1; Belongs to the V-ATPase proteolipid subunit family. (205 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
LOC102729200Collagen alpha-1(IV) chain-like. (863 aa)
LOC102729499Collagen alpha-1(IV) chain-like. (112 aa)
CASP8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2-like. (337 aa)
LOC102740057Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (186 aa)
LOC102745316Von Willebrand factor-like. (532 aa)
LAMB2Laminin subunit beta-2 isoform X1. (1801 aa)
LAMA5Laminin subunit alpha-5-like. (1341 aa)
LOC102729504Apoptosis regulator BAX-like. (212 aa)
LOC102736544Thrombospondin-4-like. (685 aa)
LOC102750316Hairy/enhancer-of-split related with YRPW motif protein 1-like isoform X2. (304 aa)
LOC102730629Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (288 aa)
FOXO1Forkhead box protein O1-like. (418 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (161 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
LOC102734846V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
LOC102730118V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC102738667Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1-like. (380 aa)
LOC102726484Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (207 aa)
LOC102749847Tyrosine-protein kinase JAK1-like. (444 aa)
LOC102729516Mastermind-like protein 2-like. (421 aa)
LOC102726878V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (393 aa)
LLGL2Lethal(2) giant larvae protein homolog 2. (1021 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
LOC102727373Integrin alpha-10-like. (374 aa)
COL1A2Collagen alpha-2(I) chain. (1365 aa)
ATP6V0E2V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa)
LOC102739066GTP-binding protein Rheb-like. (142 aa)
PTGS2Prostaglandin G/H synthase 2. (470 aa)
LOC102740357Cell division control protein 42 homolog. (191 aa)
PPP2CBSerine/threonine-protein phosphatase. (308 aa)
VTNVitronectin. (456 aa)
EP300Histone acetyltransferase p300. (2425 aa)
LFNGbeta-1,3-N-acetylglucosaminyltransferase lunatic fringe. (275 aa)
CCNE2G1/S-specific cyclin-E2; Belongs to the cyclin family. (344 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (876 aa)
ATP6V1G3V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
COL9A1Collagen alpha-1(IX) chain. (885 aa)
COL2A1Collagen alpha-1(II) chain isoform X1. (1487 aa)
RHEBL1GTPase RhebL1. (183 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
CCND3G1/S-specific cyclin-D3 isoform X1; Belongs to the cyclin family. (291 aa)
LAMC1Laminin subunit gamma-1. (1608 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
ITGA7Integrin alpha-7; Belongs to the integrin alpha chain family. (1181 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1054 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
LPXNLeupaxin; Belongs to the paxillin family. (386 aa)
NRASGTPase NRas. (189 aa)
LRRC1Leucine-rich repeat-containing protein 1. (242 aa)
LOC102746429Na(+)/H(+) exchange regulatory cofactor NHE-RF1-like. (222 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (149 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1. (1153 aa)
KRASGTPase KRas isoform X2. (188 aa)
ATP6V0D2V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (351 aa)
LOC102746125LOW QUALITY PROTEIN: cyclin-A1-like; Belongs to the cyclin family. (463 aa)
SPP1Osteopontin isoform X1. (299 aa)
IBSPBone sialoprotein 2. (318 aa)
LOC102745703Pyruvate kinase; Belongs to the pyruvate kinase family. (610 aa)
PARD6BPartitioning defective 6 homolog beta. (370 aa)
AXIN1Axin-1 isoform X1. (867 aa)
ITGA10LOW QUALITY PROTEIN: integrin alpha-10; Belongs to the integrin alpha chain family. (1165 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (693 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (557 aa)
ISG15Ubiquitin-like protein ISG15. (169 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (254 aa)
COL4A1Collagen alpha-1(IV) chain. (321 aa)
LOC102737670Cyclin-dependent kinase 6-like. (322 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
LOC102747757Interferon alpha-1/2-like. (187 aa)
LOC102747471Interferon alpha-1/2-like. (187 aa)
IFNB1Interferon beta. (182 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (489 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
RBL1Retinoblastoma-like protein 1. (1068 aa)
HDAC1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (482 aa)
DLG2Disks large homolog 2 isoform X1. (905 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (852 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
MPP5MAGUK p55 subfamily member 5; Belongs to the MAGUK family. (675 aa)
LOC102731565Laminin subunit gamma-3-like. (231 aa)
IRF1Interferon regulatory factor. (322 aa)
ATP6V1DV-type proton ATPase subunit D. (257 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102730129Uncharacterized protein LOC102730129. (471 aa)
IFNA14LOW QUALITY PROTEIN: interferon, alpha 14. (182 aa)
THBS3Thrombospondin-3 isoform X1. (956 aa)
LOC102745146Tumor necrosis factor ligand superfamily member 6-like; Belongs to the tumor necrosis factor family. (173 aa)
FN1Fibronectin isoform X1. (2476 aa)
FZD3Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
RBPJLRecombining binding protein suppressor of hairless-like protein. (517 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
FZD2Frizzled-2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
VWFVon Willebrand factor. (2285 aa)
GPSM3G-protein-signaling modulator 3 isoform X1. (162 aa)
NOTCH4Neurogenic locus notch homolog protein 4 isoform X1. (1996 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (543 aa)
TBPL2TATA box-binding protein-like protein 2. (344 aa)
LOC102743194V-type proton ATPase subunit d 2-like. (302 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (676 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (218 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
LOC102745156Catenin beta-1-like isoform X1. (216 aa)
DLG3Disks large homolog 3 isoform X1; Belongs to the MAGUK family. (512 aa)
EIF2AK2Interferon-induced, double-stranded RNA-activated protein kinase. (541 aa)
COL9A2Collagen alpha-2(IX) chain. (595 aa)
FASLGTumor necrosis factor ligand superfamily member 6. (130 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
OASL2'-5'-oligoadenylate synthase-like protein isoform X1. (514 aa)
CHD4chromodomain-helicase-DNA-binding protein 4 isoform X2. (1912 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (358 aa)
COL9A3Collagen alpha-3(IX) chain. (681 aa)
BAK1Bcl-2 homologous antagonist/killer. (211 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa)
ALOXE3Hydroperoxide isomerase ALOXE3. (711 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
ERASGTPase ERas. (233 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
TUBG1Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (451 aa)
TUBG2Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (451 aa)
LOC102746195DLA class I histocompatibility antigen, A9/A9 alpha chain-like. (189 aa)
IRF9Interferon regulatory factor 9 isoform X1. (445 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (466 aa)
LOC102749767Integrin alpha-IIb-like. (534 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
TCF7L1Transcription factor 7-like 1. (438 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
LOC102727975V-type proton ATPase subunit E 1-like isoform X1. (226 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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