STRINGSTRING
LOC102748147 LOC102748147 LOC102729504 LOC102729504 FGF2 FGF2 LOC102740654 LOC102740654 GNB4 GNB4 LOC102740057 LOC102740057 CASP8 CASP8 IFNAR1 IFNAR1 CASP9 CASP9 LOC102726062 LOC102726062 LOC102747337 LOC102747337 UBA52 UBA52 E2F3 E2F3 LOC102736516 LOC102736516 PDGFB PDGFB CREBBP CREBBP GNG2 GNG2 TYK2 TYK2 ICAM1 ICAM1 GNG4 GNG4 LOC102725943 LOC102725943 NFATC1 NFATC1 PIK3CA PIK3CA LOC102736718 LOC102736718 FOS FOS LOC102725545 LOC102725545 PIK3CD PIK3CD CALM3 CALM3 GNG8 GNG8 CASP3 CASP3 CCND1 CCND1 LOC102735415 LOC102735415 LOC102730789 LOC102730789 IKBKB IKBKB ITPR3 ITPR3 MAPK1 MAPK1 ZFP36 ZFP36 IL6 IL6 LOC102729256 LOC102729256 GSK3B GSK3B ITPR1 ITPR1 LOC102748381 LOC102748381 IRF7 IRF7 TRADD TRADD GNGT2 GNGT2 ANGPT2 ANGPT2 CHUK CHUK STAT2 STAT2 RB1 RB1 RAF1 RAF1 CDK4 CDK4 AKT3 AKT3 LOC102745475 LOC102745475 JUN JUN IKBKG IKBKG GNG13 GNG13 GABARAP GABARAP TP53 TP53 TCF7L1 TCF7L1 MAP2K2 MAP2K2 IRF9 IRF9 LOC102746195 LOC102746195 LOC102745161 LOC102745161 HIF1A HIF1A ERAS ERAS AKT1 AKT1 MAPK8 MAPK8 BAK1 BAK1 ITPR2 ITPR2 TNFRSF1A TNFRSF1A GNB3 GNB3 E2F2 E2F2 EIF2AK2 EIF2AK2 LOC102745156 LOC102745156 JAK2 JAK2 GNG5 GNG5 FADD FADD ATG14 ATG14 LOC102750923 LOC102750923 CCR4 CCR4 LOC102736922 LOC102736922 LEF1 LEF1 LOC102743442 LOC102743442 PPP3R2 PPP3R2 KRAS KRAS LOC102726446 LOC102726446 NRAS NRAS CSDE1 CSDE1 PIK3R3 PIK3R3 MAPK10 MAPK10 MAP2K1 MAP2K1 IL8 IL8 PPP3R1 PPP3R1 EP300 EP300 PIK3C3 PIK3C3 NFATC3 NFATC3 GNG3 GNG3 PTGS2 PTGS2 LOC102728200 LOC102728200 CLEC2B CLEC2B MAP2K6 MAP2K6 NFKBIA NFKBIA LOC102738071 LOC102738071 GABARAPL1 GABARAPL1 NFKB1 NFKB1 LOC102750322 LOC102750322 LOC102737670 LOC102737670 GNGT1 GNGT1 GNG11 GNG11 LOC102747757 LOC102747757 LOC102747471 LOC102747471 IFNB1 IFNB1 LOC102725978 LOC102725978 GNB5 GNB5 CREB1 CREB1 GNG10 GNG10 SRC SRC GNB2 GNB2 MAP2K7 MAP2K7 LOC102728215 LOC102728215 MAPK12 MAPK12 PREX1 PREX1 MTOR MTOR IFNA14 IFNA14 CALML4 CALML4 LOC102734861 LOC102734861 LOC102730129 LOC102730129 LOC102751021 LOC102751021 LOC102734169 LOC102734169 LOC102746862 LOC102746862 LOC102742576 LOC102742576 MAPK11 MAPK11 LOC102749847 LOC102749847 LOC102748949 LOC102748949 LOC102733954 LOC102733954 LOC102748833 LOC102748833 CSF2 CSF2 LOC102735556 LOC102735556 CDKN1A CDKN1A CCR5 CCR5 CCR1 CCR1 STAT3 STAT3 CCR3 CCR3
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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LOC102748147Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC102729504Apoptosis regulator BAX-like. (212 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (113 aa)
LOC102740654Phosphoinositide 3-kinase regulatory subunit 5-like. (111 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
LOC102740057Vascular endothelial growth factor A-like isoform X1; Belongs to the PDGF/VEGF growth factor family. (186 aa)
CASP8Caspase-8 isoform X1; Belongs to the peptidase C14A family. (486 aa)
IFNAR1Interferon alpha/beta receptor 1. (560 aa)
CASP9Caspase-9. (171 aa)
LOC102726062Uncharacterized protein C7orf31 homolog. (590 aa)
LOC102747337ubiquitin-40S ribosomal protein S27a-like. (154 aa)
UBA52ubiquitin-60S ribosomal protein L40 isoform X3. (128 aa)
E2F3Transcription factor E2F3-like isoform X1. (465 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
CREBBPCREB-binding protein-like. (1411 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
TYK2Non-receptor tyrosine-protein kinase TYK2-like. (767 aa)
ICAM1Intercellular adhesion molecule 1. (533 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
LOC102725943Nuclear factor of activated T-cells, cytoplasmic 2-like. (160 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1. (221 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC102736718Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
LOC102725545Caspase-9-like; Belongs to the peptidase C14A family. (275 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
CALM3Calmodulin isoform X1; Belongs to the calmodulin family. (149 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
CASP3Caspase-3; Belongs to the peptidase C14A family. (302 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (214 aa)
LOC102735415Phosphoinositide phospholipase C. (309 aa)
LOC102730789TNF receptor-associated factor 3-like. (295 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (557 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
ZFP36Tristetraprolin. (325 aa)
IL6Interleukin-6 isoform X1. (212 aa)
LOC102729256TNF receptor-associated factor 3-like. (283 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (1244 aa)
LOC102748381Inhibitor of nuclear factor kappa-B kinase subunit epsilon-like. (618 aa)
IRF7Interferon regulatory factor 7. (470 aa)
TRADDTumor necrosis factor receptor type 1-associated DEATH domain protein. (312 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ANGPT2Angiopoietin-2 isoform X1. (495 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
STAT2Signal transducer and activator of transcription. (854 aa)
RB1Retinoblastoma-associated protein. (846 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
LOC102745475Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like isoform X1. (340 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (335 aa)
IKBKGNF-kappa-B essential modulator isoform X2. (419 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
GABARAPGamma-aminobutyric acid receptor-associated protein. (117 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (381 aa)
TCF7L1Transcription factor 7-like 1. (438 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
IRF9Interferon regulatory factor 9 isoform X1. (445 aa)
LOC102746195DLA class I histocompatibility antigen, A9/A9 alpha chain-like. (189 aa)
LOC102745161Signal transducer and activator of transcription 3-like. (301 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (823 aa)
ERASGTPase ERas. (233 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
BAK1Bcl-2 homologous antagonist/killer. (211 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2-like. (2701 aa)
TNFRSF1ATumor necrosis factor receptor superfamily member 1A. (358 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3. (340 aa)
E2F2Transcription factor E2F2. (440 aa)
EIF2AK2Interferon-induced, double-stranded RNA-activated protein kinase. (541 aa)
LOC102745156Catenin beta-1-like isoform X1. (216 aa)
JAK2Tyrosine-protein kinase. (952 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (218 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (492 aa)
LOC102750923Cytochrome c-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
CCR4c-C chemokine receptor type 4; Belongs to the G-protein coupled receptor 1 family. (360 aa)
LOC102736922Calmodulin-like; Belongs to the calmodulin family. (223 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
LOC102743442Autophagy-related protein 3. (314 aa)
PPP3R2Calcineurin subunit B type 2. (170 aa)
KRASGTPase KRas isoform X2. (188 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
NRASGTPase NRas. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
IL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
PPP3R1Calcineurin subunit B type 1 isoform X1. (170 aa)
EP300Histone acetyltransferase p300. (2425 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (811 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3 isoform X1. (1075 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PTGS2Prostaglandin G/H synthase 2. (470 aa)
LOC102728200ubiquitin-40S ribosomal protein S27a-like. (154 aa)
CLEC2BC-type lectin domain family 2 member B. (146 aa)
MAP2K6Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
NFKBIANF-kappa-B inhibitor alpha isoform X2. (314 aa)
LOC102738071Calmodulin-like; Belongs to the calmodulin family. (113 aa)
GABARAPL1Gamma-aminobutyric acid receptor-associated protein-like 1 isoform X1. (117 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (254 aa)
LOC102750322polyubiquitin-B-like. (153 aa)
LOC102737670Cyclin-dependent kinase 6-like. (322 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC102747757Interferon alpha-1/2-like. (187 aa)
LOC102747471Interferon alpha-1/2-like. (187 aa)
IFNB1Interferon beta. (182 aa)
LOC102725978Cytochrome c 2-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (109 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (345 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
SRCTyrosine-protein kinase. (536 aa)
GNB2Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform X1. (340 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
LOC102728215Complement C3-like. (768 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
PREX1Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein. (1642 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
IFNA14LOW QUALITY PROTEIN: interferon, alpha 14. (182 aa)
CALML4LOW QUALITY PROTEIN: calmodulin-like 4. (199 aa)
LOC102734861BH3-interacting domain death agonist-like. (83 aa)
LOC102730129Uncharacterized protein LOC102730129. (471 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
LOC102734169Gamma-aminobutyric acid receptor-associated protein-like 2-like. (117 aa)
LOC102746862ubiquitin-40S ribosomal protein S27a-like isoform X1. (156 aa)
LOC102742576C-X-C motif chemokine. (107 aa)
MAPK11Mitogen-activated protein kinase. (254 aa)
LOC102749847Tyrosine-protein kinase JAK1-like. (444 aa)
LOC102748949Calcipressin-1-like. (140 aa)
LOC102733954Calmodulin-like protein 4-like. (119 aa)
LOC102748833Tyrosine-protein kinase. (375 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (153 aa)
LOC102735556Mitogen-activated protein kinase 9-like. (134 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (161 aa)
CCR5c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
CCR1c-C chemokine receptor type 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
STAT3Signal transducer and activator of transcription 3-like. (424 aa)
CCR3c-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (359 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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