STRINGSTRING
LOC102746125 LOC102746125 KRAS KRAS LOC102726446 LOC102726446 NRAS NRAS CSDE1 CSDE1 PIK3R3 PIK3R3 MAP2K1 MAP2K1 ITGAM ITGAM SPI1 SPI1 NFKB1 NFKB1 LOC102751021 LOC102751021 PIM1 PIM1 ZBTB16 ZBTB16 MTOR MTOR LOC102750159 LOC102750159 PPARD PPARD AKT1 AKT1 PIM2 PIM2 ERAS ERAS LOC102745161 LOC102745161 STAT5B STAT5B MAP2K2 MAP2K2 TCF7L1 TCF7L1 LOC102747288 LOC102747288 DUSP6 DUSP6 IKBKG IKBKG BCL2A1 BCL2A1 AKT3 AKT3 RAF1 RAF1 RPS6KB1 RPS6KB1 PML PML CHUK CHUK CSF1R CSF1R MAPK1 MAPK1 IKBKB IKBKB JUP JUP CCND1 CCND1 PIK3CD PIK3CD PIK3CA PIK3CA RARA RARA FLT3 FLT3 CEBPE CEBPE LOC102736516 LOC102736516 LOC102749709 LOC102749709 MPO MPO SPIB SPIB STAT5A STAT5A STAT3 STAT3 IL3 IL3 LOC102729819 LOC102729819 CSF2 CSF2 RPS6KB2 RPS6KB2 LOC102742177 LOC102742177 LOC102731864 LOC102731864 LEF1 LEF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102746125LOW QUALITY PROTEIN: cyclin-A1-like; Belongs to the cyclin family. (463 aa)
KRASGTPase KRas isoform X2. (188 aa)
LOC102726446Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like; Belongs to the PI3/PI4-kinase family. (235 aa)
NRASGTPase NRas. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (845 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
ITGAMIntegrin alpha-M isoform X1; Belongs to the integrin alpha chain family. (1154 aa)
SPI1Transcription factor PU.1. (250 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit. (254 aa)
LOC102751021Phosphatidylinositol 3-kinase regulatory subunit alpha-like isoform X1. (454 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
ZBTB16Zinc finger and BTB domain-containing protein 16 isoform X1. (673 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2550 aa)
LOC102750159Junction plakoglobin-like. (503 aa)
PPARDPeroxisome proliferator-activated receptor delta isoform X1. (441 aa)
AKT1Non-specific serine/threonine protein kinase. (518 aa)
PIM2Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (311 aa)
ERASGTPase ERas. (233 aa)
LOC102745161Signal transducer and activator of transcription 3-like. (301 aa)
STAT5BSignal transducer and activator of transcription 5B. (508 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
TCF7L1Transcription factor 7-like 1. (438 aa)
LOC102747288CCAAT/enhancer-binding protein alpha-like. (178 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
IKBKGNF-kappa-B essential modulator isoform X2. (419 aa)
BCL2A1Bcl-2-related protein A1. (174 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (418 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
RPS6KB1Non-specific serine/threonine protein kinase. (445 aa)
PMLProtein PML. (880 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha. (745 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (326 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta isoform X1. (756 aa)
JUPJunction plakoglobin. (307 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (214 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1043 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
RARARetinoic acid receptor alpha isoform X1. (462 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (984 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
LOC102736516Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (138 aa)
LOC102749709CCAAT/enhancer-binding protein alpha-like. (165 aa)
MPOMyeloperoxidase isoform X2. (718 aa)
SPIBTranscription factor Spi-B isoform X1. (262 aa)
STAT5ASignal transducer and activator of transcription 5A. (464 aa)
STAT3Signal transducer and activator of transcription 3-like. (424 aa)
IL3Interleukin-3. (143 aa)
LOC102729819Protein CBFA2T1-like. (287 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (153 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
LOC102742177Mast/stem cell growth factor receptor Kit-like. (217 aa)
LOC102731864Signal transducer and activator of transcription 5B-like. (353 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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