20 items (Leptonychotes weddellii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	PRG3	LOW QUALITY PROTEIN: proteoglycan 3. (249 aa)
	IL10	Interleukin-10. (178 aa)
	IL4	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (131 aa)
	IL5	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
	IL13	Interleukin-13. (133 aa)
	LOC102740784	HLA class II histocompatibility antigen, DR alpha chain-like; Belongs to the MHC class II family. (254 aa)
	LOC102741082	DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa)
	LOC102748462	HLA class II histocompatibility antigen, DO beta chain-like. (273 aa)
	LOC102750454	HLA class II histocompatibility antigen, DM alpha chain-like; Belongs to the MHC class II family. (261 aa)
	LOC102750166	HLA class II histocompatibility antigen, DM beta chain-like. (263 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	CD40	Tumor necrosis factor receptor superfamily member 5. (272 aa)
	FCER1A	High affinity immunoglobulin epsilon receptor subunit alpha. (264 aa)
	FCER1G	High affinity immunoglobulin epsilon receptor subunit gamma. (94 aa)
	IL9	Interleukin-9. (142 aa)
	CD40LG	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa)
	MS4A2	High affinity immunoglobulin epsilon receptor subunit beta. (242 aa)
	EPX	Eosinophil peroxidase. (732 aa)
	LOC102734456	HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa)
	IL3	Interleukin-3. (143 aa)

Your Current Organism:

Leptonychotes weddellii

NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD40	CD40LG	A0A2U3Y7Z8	A0A2U3YMY4	Tumor necrosis factor receptor superfamily member 5.	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	0.999
CD40	IL10	A0A2U3Y7Z8	A0A2U3XRS9	Tumor necrosis factor receptor superfamily member 5.	Interleukin-10.	0.725
CD40	IL13	A0A2U3Y7Z8	A0A2U3XTH0	Tumor necrosis factor receptor superfamily member 5.	Interleukin-13.	0.556
CD40	IL4	A0A2U3Y7Z8	A0A2U3XTG1	Tumor necrosis factor receptor superfamily member 5.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.808
CD40	IL5	A0A2U3Y7Z8	A0A2U3XTG3	Tumor necrosis factor receptor superfamily member 5.	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.	0.543
CD40	TNF	A0A2U3Y7Z8	A0A2U3Y499	Tumor necrosis factor receptor superfamily member 5.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.846
CD40LG	CD40	A0A2U3YMY4	A0A2U3Y7Z8	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor receptor superfamily member 5.	0.999
CD40LG	IL10	A0A2U3YMY4	A0A2U3XRS9	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Interleukin-10.	0.769
CD40LG	IL13	A0A2U3YMY4	A0A2U3XTH0	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Interleukin-13.	0.596
CD40LG	IL3	A0A2U3YMY4	A0A2U3Z570	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Interleukin-3.	0.442
CD40LG	IL4	A0A2U3YMY4	A0A2U3XTG1	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family.	0.856
CD40LG	IL5	A0A2U3YMY4	A0A2U3XTG3	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells.	0.541
CD40LG	IL9	A0A2U3YMY4	A0A2U3YLZ0	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Interleukin-9.	0.518
CD40LG	TNF	A0A2U3YMY4	A0A2U3Y499	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.795
EPX	IL10	A0A2U3YYY7	A0A2U3XRS9	Eosinophil peroxidase.	Interleukin-10.	0.491
EPX	TNF	A0A2U3YYY7	A0A2U3Y499	Eosinophil peroxidase.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.502
FCER1A	FCER1G	A0A2U3YE63	A0A2U3YL68	High affinity immunoglobulin epsilon receptor subunit alpha.	High affinity immunoglobulin epsilon receptor subunit gamma.	0.943
FCER1A	IL10	A0A2U3YE63	A0A2U3XRS9	High affinity immunoglobulin epsilon receptor subunit alpha.	Interleukin-10.	0.411
FCER1A	IL13	A0A2U3YE63	A0A2U3XTH0	High affinity immunoglobulin epsilon receptor subunit alpha.	Interleukin-13.	0.404
FCER1A	MS4A2	A0A2U3YE63	A0A2U3YSY3	High affinity immunoglobulin epsilon receptor subunit alpha.	High affinity immunoglobulin epsilon receptor subunit beta.	0.989