STRINGSTRING
LOC102750454 LOC102750454 CD28 CD28 IL1A IL1A IL1B IL1B IL6 IL6 IFNG IFNG LOC102746195 LOC102746195 TNF TNF IL2 IL2 LOC102750166 LOC102750166 PRF1 PRF1 LOC102748462 LOC102748462 FASLG FASLG LOC102741082 LOC102741082 LOC102740784 LOC102740784 LOC102745146 LOC102745146 CD80 CD80 LOC102730741 LOC102730741 LOC102734456 LOC102734456
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102750454HLA class II histocompatibility antigen, DM alpha chain-like; Belongs to the MHC class II family. (261 aa)
CD28T-cell-specific surface glycoprotein CD28. (209 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (265 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (270 aa)
IL6Interleukin-6 isoform X1. (212 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
LOC102746195DLA class I histocompatibility antigen, A9/A9 alpha chain-like. (189 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
LOC102750166HLA class II histocompatibility antigen, DM beta chain-like. (263 aa)
PRF1Perforin-1. (555 aa)
LOC102748462HLA class II histocompatibility antigen, DO beta chain-like. (273 aa)
FASLGTumor necrosis factor ligand superfamily member 6. (130 aa)
LOC102741082DLA class II histocompatibility antigen, DR-1 beta chain-like. (266 aa)
LOC102740784HLA class II histocompatibility antigen, DR alpha chain-like; Belongs to the MHC class II family. (254 aa)
LOC102745146Tumor necrosis factor ligand superfamily member 6-like; Belongs to the tumor necrosis factor family. (173 aa)
CD80LOW QUALITY PROTEIN: T-lymphocyte activation antigen CD80. (295 aa)
LOC102730741Natural killer cells antigen CD94-like. (162 aa)
LOC102734456HLA class II histocompatibility antigen, DO alpha chain-like; Belongs to the MHC class II family. (250 aa)
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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