(22 nodes) Valine, leucine and isoleucine biosynthesis network (Arthrobotrys flagrans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DFL_008159	ACT domain-containing protein. (309 aa)
	DFL_002534	Threonine dehydratase. (545 aa)
	DFL_001678	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa)
	DFL_005298	Uncharacterized protein. (601 aa)
	DFL_001550	Pyruvate carboxyltransferase domain-containing protein. (600 aa)
	DFL_005346	Uncharacterized protein. (402 aa)
	DFL_005283	Uncharacterized protein. (229 aa)
	DFL_005149	Uncharacterized protein. (387 aa)
	DFL_004616	Acetolactate synthase. (693 aa)
	DFL_004052	Uncharacterized protein. (579 aa)
	DFL_005517	PALP domain-containing protein. (382 aa)
	DFL_005526	Uncharacterized protein. (503 aa)
	DFL_007913	PALP domain-containing protein. (377 aa)
	DFL_007501	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
	DFL_007215	HET domain-containing protein. (596 aa)
	DFL_009478	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (408 aa)
	DFL_009349	Uncharacterized protein. (351 aa)
	DFL_009148	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
	DFL_008914	Uncharacterized protein. (352 aa)
	DFL_008247	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (768 aa)
	DFL_000074	Uncharacterized protein. (343 aa)
	DFL_001412	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (624 aa)

Your Current Organism:

Arthrobotrys flagrans

NCBI taxonomy Id: 97331
Other names: A. flagrans, Duddingtonia flagrans, Trichothecium flagrans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DFL_000074	DFL_001412	A0A437ADA3	A0A437AH28	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.671
DFL_000074	DFL_001550	A0A437ADA3	A0A437A7Y3	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein.	0.671
DFL_000074	DFL_002534	A0A437ADA3	A0A437AAR3	Uncharacterized protein.	Threonine dehydratase.	0.518
DFL_000074	DFL_004052	A0A437ADA3	A0A437A3K5	Uncharacterized protein.	Uncharacterized protein.	0.476
DFL_000074	DFL_004616	A0A437ADA3	A0A437A567	Uncharacterized protein.	Acetolactate synthase.	0.647
DFL_000074	DFL_005298	A0A437ADA3	A0A437A802	Uncharacterized protein.	Uncharacterized protein.	0.476
DFL_000074	DFL_005517	A0A437ADA3	A0A436ZXV2	Uncharacterized protein.	PALP domain-containing protein.	0.518
DFL_000074	DFL_007501	A0A437ADA3	A0A436ZVZ9	Uncharacterized protein.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.402
DFL_000074	DFL_007913	A0A437ADA3	A0A436ZX20	Uncharacterized protein.	PALP domain-containing protein.	0.518
DFL_000074	DFL_008159	A0A437ADA3	A0A436ZMY6	Uncharacterized protein.	ACT domain-containing protein.	0.760
DFL_000074	DFL_008247	A0A437ADA3	A0A436ZN62	Uncharacterized protein.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.853
DFL_000074	DFL_009349	A0A437ADA3	A0A436ZRI0	Uncharacterized protein.	Uncharacterized protein.	0.647
DFL_001412	DFL_000074	A0A437AH28	A0A437ADA3	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Uncharacterized protein.	0.671
DFL_001412	DFL_001678	A0A437AH28	A0A437A8B0	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	0.694
DFL_001412	DFL_004052	A0A437AH28	A0A437A3K5	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Uncharacterized protein.	0.844
DFL_001412	DFL_004616	A0A437AH28	A0A437A567	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Acetolactate synthase.	0.728
DFL_001412	DFL_005149	A0A437AH28	A0A437A700	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Uncharacterized protein.	0.671
DFL_001412	DFL_005283	A0A437AH28	A0A437A770	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Uncharacterized protein.	0.670
DFL_001412	DFL_005298	A0A437AH28	A0A437A802	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Uncharacterized protein.	0.844
DFL_001412	DFL_005346	A0A437AH28	A0A437A7F8	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	Uncharacterized protein.	0.671