STRINGSTRING
DFL_001911 DFL_001911 DFL_008150 DFL_008150 DFL_008219 DFL_008219 DFL_008233 DFL_008233 DFL_008324 DFL_008324 DFL_008318 DFL_008318 DFL_008433 DFL_008433 DFL_008430 DFL_008430 DFL_008538 DFL_008538 DFL_008606 DFL_008606 DFL_008705 DFL_008705 DFL_008663 DFL_008663 DFL_008775 DFL_008775 DFL_008794 DFL_008794 DFL_008792 DFL_008792 DFL_008869 DFL_008869 DFL_008871 DFL_008871 DFL_009023 DFL_009023 DFL_009032 DFL_009032 DFL_009125 DFL_009125 DFL_009166 DFL_009166 DFL_009056 DFL_009056 DFL_009236 DFL_009236 DFL_009252 DFL_009252 DFL_009337 DFL_009337 DFL_009464 DFL_009464 DFL_009599 DFL_009599 DFL_009453 DFL_009453 DFL_009618 DFL_009618 DFL_009662 DFL_009662 DFL_009865 DFL_009865 DFL_009801 DFL_009801 DFL_009920 DFL_009920 DFL_006608 DFL_006608 DFL_009898 DFL_009898 DFL_006619 DFL_006619 DFL_006732 DFL_006732 DFL_006825 DFL_006825 DFL_006792 DFL_006792 DFL_006909 DFL_006909 DFL_007222 DFL_007222 DFL_007229 DFL_007229 DFL_007211 DFL_007211 DFL_007256 DFL_007256 DFL_007213 DFL_007213 DFL_007150 DFL_007150 DFL_007361 DFL_007361 DFL_007415 DFL_007415 TRM8 TRM8 DFL_007205 DFL_007205 DFL_007332 DFL_007332 DFL_007473 DFL_007473 DFL_007350 DFL_007350 DFL_007560 DFL_007560 DFL_007586 DFL_007586 DFL_007645 DFL_007645 DFL_007761 DFL_007761 DFL_007853 DFL_007853 DFL_007670 DFL_007670 DFL_007913 DFL_007913 DFL_008006 DFL_008006 DFL_005437 DFL_005437 DFL_005450 DFL_005450 DFL_005449 DFL_005449 DFL_005448 DFL_005448 DFL_005517 DFL_005517 DFL_005490 DFL_005490 DFL_005436 DFL_005436 DFL_005682 DFL_005682 DFL_005847 DFL_005847 DFL_005597 DFL_005597 DFL_005896 DFL_005896 DFL_005688 DFL_005688 DFL_006039 DFL_006039 DFL_005801 DFL_005801 DFL_006096 DFL_006096 DFL_006181 DFL_006181 DFL_006241 DFL_006241 DFL_006350 DFL_006350 DFL_006468 DFL_006468 DFL_006506 DFL_006506 DFL_003467 DFL_003467 DFL_003499 DFL_003499 DFL_003562 DFL_003562 DFL_003584 DFL_003584 DFL_003641 DFL_003641 DFL_003688 DFL_003688 DFL_003743 DFL_003743 DFL_003878 DFL_003878 DFL_003875 DFL_003875 DFL_004020 DFL_004020 DFL_003995 DFL_003995 DFL_004069 DFL_004069 DFL_004135 DFL_004135 DFL_004285 DFL_004285 DFL_004461 DFL_004461 DFL_004660 DFL_004660 DFL_004746 DFL_004746 DFL_004659 DFL_004659 DFL_004760 DFL_004760 DFL_004686 DFL_004686 DFL_004941 DFL_004941 DFL_004899 DFL_004899 DFL_004826 DFL_004826 DFL_004962 DFL_004962 DFL_005044 DFL_005044 DFL_005270 DFL_005270 DFL_005181 DFL_005181 DFL_001750 DFL_001750 DFL_001798 DFL_001798 DFL_001844 DFL_001844 DFL_001859 DFL_001859 DFL_001901 DFL_001901 DFL_001964 DFL_001964 DFL_001935 DFL_001935 DFL_001963 DFL_001963 DFL_001867 DFL_001867 DFL_002251 DFL_002251 DFL_002252 DFL_002252 DFL_002211 DFL_002211 DFL_002374 DFL_002374 DFL_002464 DFL_002464 DFL_002377 DFL_002377 DFL_002534 DFL_002534 DFL_002343 DFL_002343 DFL_002382 DFL_002382 DFL_002450 DFL_002450 DFL_002457 DFL_002457 DFL_002770 DFL_002770 DFL_002835 DFL_002835 DFL_002729 DFL_002729 DFL_002994 DFL_002994 DFL_000019 DFL_000019 DFL_000006 DFL_000006 DFL_002866 DFL_002866 DFL_000305 DFL_000305 DFL_000323 DFL_000323 DFL_000669 DFL_000669 DFL_000198 DFL_000198 DFL_000812 DFL_000812 DFL_000961 DFL_000961 DFL_000991 DFL_000991 DFL_001040 DFL_001040 DFL_001083 DFL_001083 DFL_001112 DFL_001112 DFL_001186 DFL_001186 DFL_001303 DFL_001303 DFL_001302 DFL_001302 DFL_001390 DFL_001390 DFL_001367 DFL_001367
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DFL_0019116-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (256 aa)
DFL_008150Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (387 aa)
DFL_008219MaoC-like domain-containing protein. (901 aa)
DFL_008233MFS domain-containing protein. (527 aa)
DFL_008324Uncharacterized protein. (172 aa)
DFL_008318Uncharacterized protein. (772 aa)
DFL_008433Pyr_redox_2 domain-containing protein. (349 aa)
DFL_008430WW domain-containing protein. (298 aa)
DFL_008538Uncharacterized protein. (459 aa)
DFL_0086063-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (482 aa)
DFL_008705PNPLA domain-containing protein. (437 aa)
DFL_008663Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (792 aa)
DFL_008775Dihydrolipoyl dehydrogenase. (510 aa)
DFL_008794Uncharacterized protein. (514 aa)
DFL_008792Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (469 aa)
DFL_008869PNPLA domain-containing protein. (957 aa)
DFL_008871Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (281 aa)
DFL_009023Uncharacterized protein. (443 aa)
DFL_009032Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1214 aa)
DFL_009125Aminotran_5 domain-containing protein. (459 aa)
DFL_009166Zn(2)-C6 fungal-type domain-containing protein. (681 aa)
DFL_009056MACPF domain-containing protein. (728 aa)
DFL_009236MACPF domain-containing protein. (617 aa)
DFL_009252Catalase domain-containing protein. (589 aa)
DFL_009337Mac domain-containing protein. (217 aa)
DFL_009464Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (489 aa)
DFL_009599Citrate synthase; Belongs to the citrate synthase family. (470 aa)
DFL_009453Isocitrate lyase. (538 aa)
DFL_009618Malic enzyme. (692 aa)
DFL_009662Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (664 aa)
DFL_009865Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (486 aa)
DFL_009801FMN hydroxy acid dehydrogenase domain-containing protein. (413 aa)
DFL_009920Peripheral subunit-binding (PSBD) domain-containing protein. (285 aa)
DFL_006608Uncharacterized protein. (415 aa)
DFL_009898PNPLA domain-containing protein. (753 aa)
DFL_006619Pribosyltran_N domain-containing protein. (354 aa)
DFL_006732MFS domain-containing protein. (515 aa)
DFL_006825Bms1-type G domain-containing protein. (776 aa)
DFL_006792Aspartate aminotransferase. (430 aa)
DFL_006909Phosphotransferase. (497 aa)
DFL_007222PALP domain-containing protein. (441 aa)
DFL_007229Aldedh domain-containing protein. (574 aa)
DFL_007211RyR domain-containing protein. (198 aa)
DFL_007256Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (511 aa)
DFL_007213Uncharacterized protein. (848 aa)
DFL_007150Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (651 aa)
DFL_007361Transket_pyr domain-containing protein. (1031 aa)
DFL_007415Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (221 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (293 aa)
DFL_007205Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
DFL_007332SET domain-containing protein. (605 aa)
DFL_007473Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (480 aa)
DFL_007350FBPase domain-containing protein; Belongs to the FBPase class 1 family. (345 aa)
DFL_007560Uncharacterized protein. (264 aa)
DFL_007586Catalase domain-containing protein. (298 aa)
DFL_007645Probable acetate kinase. (435 aa)
DFL_007761Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (625 aa)
DFL_007853PNPLA domain-containing protein. (1253 aa)
DFL_007670Uncharacterized protein. (425 aa)
DFL_007913PALP domain-containing protein. (377 aa)
DFL_008006Uncharacterized protein. (285 aa)
DFL_005437Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (294 aa)
DFL_005450Zn(2)-C6 fungal-type domain-containing protein. (665 aa)
DFL_005449Uncharacterized protein. (166 aa)
DFL_005448Uncharacterized protein. (589 aa)
DFL_005517PALP domain-containing protein. (382 aa)
DFL_005490Uncharacterized protein. (400 aa)
DFL_005436Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (1425 aa)
DFL_005682TRANSKETOLASE_1 domain-containing protein. (657 aa)
DFL_005847Catalase domain-containing protein. (499 aa)
DFL_005597Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (328 aa)
DFL_005896PNPLA domain-containing protein. (674 aa)
DFL_005688Uncharacterized protein. (484 aa)
DFL_006039Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (418 aa)
DFL_005801Uncharacterized protein. (265 aa)
DFL_006096TPR_REGION domain-containing protein. (385 aa)
DFL_006181Uncharacterized protein. (694 aa)
DFL_006241Lipoyl-binding domain-containing protein. (446 aa)
DFL_006350Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (323 aa)
DFL_006468Zn(2)-C6 fungal-type domain-containing protein. (702 aa)
DFL_006506Arabinan endo-1,5-alpha-L-arabinosidase; Belongs to the glycosyl hydrolase 43 family. (319 aa)
DFL_003467Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (418 aa)
DFL_003499Uncharacterized protein. (879 aa)
DFL_003562ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (1366 aa)
DFL_003584Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (444 aa)
DFL_003641Pribosyltran_N domain-containing protein. (542 aa)
DFL_003688Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1101 aa)
DFL_003743Uncharacterized protein. (451 aa)
DFL_003878Uncharacterized protein. (412 aa)
DFL_003875S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (380 aa)
DFL_004020Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (410 aa)
DFL_003995Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (676 aa)
DFL_004069Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (877 aa)
DFL_004135Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (241 aa)
DFL_0042856-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (522 aa)
DFL_004461Pyruvate kinase; Belongs to the pyruvate kinase family. (512 aa)
DFL_004660Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (363 aa)
DFL_004746Uncharacterized protein. (536 aa)
DFL_004659RIBOSOMAL_L9 domain-containing protein. (282 aa)
DFL_004760Triosephosphate isomerase. (248 aa)
DFL_004686Uncharacterized protein. (557 aa)
DFL_004941Phosphotransferase. (493 aa)
DFL_004899Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (245 aa)
DFL_004826Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (176 aa)
DFL_004962Uncharacterized protein. (507 aa)
DFL_005044Uncharacterized protein. (180 aa)
DFL_005270Malic enzyme. (615 aa)
DFL_005181Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (169 aa)
DFL_001750Uncharacterized protein. (499 aa)
DFL_001798Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (302 aa)
DFL_001844Malate synthase; Belongs to the malate synthase family. (540 aa)
DFL_001859Uncharacterized protein. (635 aa)
DFL_001901S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (331 aa)
DFL_001964Iso_dh domain-containing protein. (330 aa)
DFL_001935Uncharacterized protein. (400 aa)
DFL_001963Uncharacterized protein. (321 aa)
DFL_001867Citrate synthase; Belongs to the citrate synthase family. (471 aa)
DFL_002251D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (472 aa)
DFL_002252Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (328 aa)
DFL_002211PALP domain-containing protein. (369 aa)
DFL_002374Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (363 aa)
DFL_002464Phosphotransferase. (602 aa)
DFL_002377Uncharacterized protein. (641 aa)
DFL_002534Threonine dehydratase. (545 aa)
DFL_002343Uncharacterized protein; Belongs to the LDH/MDH superfamily. (331 aa)
DFL_00238225S rRNA adenine-N(1) methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA; Belongs to the BMT2 family. (333 aa)
DFL_002450Zn(2)-C6 fungal-type domain-containing protein. (1039 aa)
DFL_002457Zn(2)-C6 fungal-type domain-containing protein. (685 aa)
DFL_002770Aspartate aminotransferase. (412 aa)
DFL_002835Aminotran_1_2 domain-containing protein. (487 aa)
DFL_002729Uncharacterized protein. (804 aa)
DFL_002994Uncharacterized protein. (155 aa)
DFL_000019CBM1 domain-containing protein. (483 aa)
DFL_000006Uncharacterized protein. (269 aa)
DFL_002866Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (505 aa)
DFL_000305Uncharacterized protein. (321 aa)
DFL_000323PNPLA domain-containing protein. (600 aa)
DFL_000669Malate dehydrogenase. (343 aa)
DFL_000198Glyceraldehyde-3-phosphate dehydrogenase. (336 aa)
DFL_000812Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (384 aa)
DFL_000961Pribosyltran_N domain-containing protein. (435 aa)
DFL_000991Glucose-6-phosphate isomerase; Belongs to the GPI family. (551 aa)
DFL_001040Arabinan endo-1,5-alpha-L-arabinosidase; Belongs to the glycosyl hydrolase 43 family. (394 aa)
DFL_001083SET domain-containing protein. (420 aa)
DFL_001112Uncharacterized protein. (342 aa)
DFL_001186Uncharacterized protein. (353 aa)
DFL_001303Uncharacterized protein. (276 aa)
DFL_001302Citrate synthase; Belongs to the citrate synthase family. (486 aa)
DFL_001390Uncharacterized protein. (299 aa)
DFL_001367Zn(2)-C6 fungal-type domain-containing protein. (918 aa)
Your Current Organism:
Arthrobotrys flagrans
NCBI taxonomy Id: 97331
Other names: A. flagrans, Duddingtonia flagrans, Trichothecium flagrans
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