(48 nodes) 2-Oxocarboxylic acid metabolism network (Arthrobotrys flagrans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DFL_006732	MFS domain-containing protein. (515 aa)
	DFL_006792	Aspartate aminotransferase. (430 aa)
	DFL_007215	HET domain-containing protein. (596 aa)
	DFL_007501	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
	DFL_002385	Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (622 aa)
	DFL_002770	Aspartate aminotransferase. (412 aa)
	DFL_002835	Aminotran_1_2 domain-containing protein. (487 aa)
	DFL_000074	Uncharacterized protein. (343 aa)
	DFL_000233	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (799 aa)
	DFL_000812	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (384 aa)
	DFL_001047	Semialdhyde_dh domain-containing protein. (358 aa)
	DFL_001302	Citrate synthase; Belongs to the citrate synthase family. (486 aa)
	DFL_001412	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (624 aa)
	DFL_007681	Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (716 aa)
	DFL_005526	Uncharacterized protein. (503 aa)
	DFL_005490	Uncharacterized protein. (400 aa)
	DFL_004052	Uncharacterized protein. (579 aa)
	DFL_005298	Uncharacterized protein. (601 aa)
	DFL_001473	M20_dimer domain-containing protein. (201 aa)
	DFL_001550	Pyruvate carboxyltransferase domain-containing protein. (600 aa)
	DFL_008150	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (387 aa)
	DFL_005149	Uncharacterized protein. (387 aa)
	DFL_004552	Iso_dh domain-containing protein. (366 aa)
	DFL_004616	Acetolactate synthase. (693 aa)
	DFL_004323	Ubiquitin-like domain-containing protein. (77 aa)
	DFL_005346	Uncharacterized protein. (402 aa)
	DFL_005283	Uncharacterized protein. (229 aa)
	DFL_002753	Aspartokinase. (532 aa)
	DFL_002588	Aminotran_1_2 domain-containing protein. (615 aa)
	DFL_001867	Citrate synthase; Belongs to the citrate synthase family. (471 aa)
	DFL_008247	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (768 aa)
	DFL_008233	MFS domain-containing protein. (527 aa)
	DFL_008727	Aminotran_1_2 domain-containing protein. (546 aa)
	DFL_008663	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (792 aa)
	DFL_008914	Uncharacterized protein. (352 aa)
	DFL_009003	M20_dimer domain-containing protein. (485 aa)
	DFL_009148	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (423 aa)
	DFL_009349	Uncharacterized protein. (351 aa)
	DFL_009464	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (489 aa)
	DFL_009478	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (408 aa)
	DFL_008159	ACT domain-containing protein. (309 aa)
	DFL_001964	Iso_dh domain-containing protein. (330 aa)
	DFL_001862	N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family. (889 aa)
	DFL_009599	Citrate synthase; Belongs to the citrate synthase family. (470 aa)
	DFL_009694	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family. (463 aa)
	DFL_006721	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (447 aa)
	DFL_006805	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
	DFL_001678	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa)

Your Current Organism:

Arthrobotrys flagrans

NCBI taxonomy Id: 97331
Other names: A. flagrans, Duddingtonia flagrans, Trichothecium flagrans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DFL_000074	DFL_000233	A0A437ADA3	A0A437ADJ7	Uncharacterized protein.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.552
DFL_000074	DFL_001302	A0A437ADA3	A0A437AGT8	Uncharacterized protein.	Citrate synthase; Belongs to the citrate synthase family.	0.529
DFL_000074	DFL_001412	A0A437ADA3	A0A437AH28	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.671
DFL_000074	DFL_001550	A0A437ADA3	A0A437A7Y3	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein.	0.671
DFL_000074	DFL_001862	A0A437ADA3	A0A437A920	Uncharacterized protein.	N-acetyltransferase domain-containing protein; In the N-terminal section; belongs to the acetylglutamate kinase family.	0.545
DFL_000074	DFL_001867	A0A437ADA3	A0A437A9S0	Uncharacterized protein.	Citrate synthase; Belongs to the citrate synthase family.	0.529
DFL_000074	DFL_002770	A0A437ADA3	A0A437ABR7	Uncharacterized protein.	Aspartate aminotransferase.	0.448
DFL_000074	DFL_002835	A0A437ADA3	A0A437AC51	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.408
DFL_000074	DFL_004052	A0A437ADA3	A0A437A3K5	Uncharacterized protein.	Uncharacterized protein.	0.476
DFL_000074	DFL_004616	A0A437ADA3	A0A437A567	Uncharacterized protein.	Acetolactate synthase.	0.647
DFL_000074	DFL_005298	A0A437ADA3	A0A437A802	Uncharacterized protein.	Uncharacterized protein.	0.476
DFL_000074	DFL_005490	A0A437ADA3	A0A436ZY26	Uncharacterized protein.	Uncharacterized protein.	0.535
DFL_000074	DFL_006721	A0A437ADA3	A0A436ZTL0	Uncharacterized protein.	Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.662
DFL_000074	DFL_006792	A0A437ADA3	A0A436ZUH1	Uncharacterized protein.	Aspartate aminotransferase.	0.470
DFL_000074	DFL_007501	A0A437ADA3	A0A436ZVZ9	Uncharacterized protein.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.402
DFL_000074	DFL_007681	A0A437ADA3	A0A436ZX16	Uncharacterized protein.	Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.	0.614
DFL_000074	DFL_008159	A0A437ADA3	A0A436ZMY6	Uncharacterized protein.	ACT domain-containing protein.	0.760
DFL_000074	DFL_008247	A0A437ADA3	A0A436ZN62	Uncharacterized protein.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.853
DFL_000074	DFL_008663	A0A437ADA3	A0A436ZPP6	Uncharacterized protein.	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.	0.563
DFL_000074	DFL_009349	A0A437ADA3	A0A436ZRI0	Uncharacterized protein.	Uncharacterized protein.	0.647