STRINGSTRING
ACTL7B ACTL7B EPB41L4B EPB41L4B NF2 NF2 ARRDC3 ARRDC3 SGK1 SGK1 CYR61 CYR61 PRKCI PRKCI SKIL SKIL AMOTL2 AMOTL2 LTBP3 LTBP3 WWP1 WWP1 SPINK14 SPINK14 PARD6G PARD6G BMP2 BMP2 SMAD2 SMAD2 ACVR1B ACVR1B CCN2 CCN2 MPDZ MPDZ SMURF1 SMURF1 SMAD3 SMAD3 BAMBI BAMBI AMOT AMOT NODAL NODAL NEDD4L NEDD4L WWTR1 WWTR1 PTPN14 PTPN14 INHBA INHBA LOC101324780 LOC101324780 BMP3 BMP3 EPDR1 EPDR1 MAGI1 MAGI1 BORA BORA PIBF1 PIBF1 KLF5 KLF5 SMAD7 SMAD7 ANKFN1 ANKFN1 TGFBR2 TGFBR2 NBL1 NBL1 ACVRL1 ACVRL1 BNC1 BNC1 BMPR2 BMPR2 SCNN1B SCNN1B TEAD2 TEAD2 ACVR2B ACVR2B WWP2 WWP2 KCNJ1 KCNJ1 BMP5 BMP5 CHRDL2 CHRDL2 LATS1 LATS1 ARRDC1 ARRDC1 SCNN1G SCNN1G STK3 STK3 RAP2C RAP2C LTBP1 LTBP1 TEAD1 TEAD1 MOB1A MOB1A WWC2 WWC2 FGF14 FGF14 NUMBL NUMBL STK4 STK4 ACVR1 ACVR1 TEAD4 TEAD4 CRB3 CRB3 SMAD9 SMAD9 TTLL9 TTLL9 NEDD4 NEDD4 SMAD1 SMAD1 BMPR1A BMPR1A LLGL1 LLGL1 MOB1B MOB1B ENSTTRP00000008060 ENSTTRP00000008060 RC3H1 RC3H1 PATJ PATJ CRB1 CRB1 RNF212B RNF212B ZFYVE16 ZFYVE16 SMURF2 SMURF2 PARD3 PARD3 MAGI3 MAGI3 HECW1 HECW1 PARD6A PARD6A BMP4 BMP4 NUMB NUMB BMP15 BMP15 TEAD3 TEAD3 SAV1 SAV1 AMHR2 AMHR2 GDF11 GDF11 SOSTDC1 SOSTDC1 SKI SKI LATS2 LATS2 DRC7 DRC7 ERFE ERFE ENSTTRP00000009655 ENSTTRP00000009655 SMAD6 SMAD6 ZSWIM4 ZSWIM4 ENSTTRP00000010335 ENSTTRP00000010335 CHRD CHRD FSTL3 FSTL3 LOC101325454 LOC101325454 CRB2 CRB2 GAPT GAPT YAP1 YAP1 INHA INHA SMAD4 SMAD4 MAGI2 MAGI2 PRKCZ PRKCZ ZSWIM8 ZSWIM8 NDFIP1 NDFIP1 FST FST GDF6 GDF6 ENSTTRP00000011729 ENSTTRP00000011729 ITCH ITCH FRMD6 FRMD6 SALL2 SALL2 TGFB1 TGFB1 INHBC INHBC INHBE INHBE GDF2 GDF2 RAPGEF6 RAPGEF6 BMP10 BMP10 TGFB2 TGFB2 TGFBR1 TGFBR1 NDFIP2 NDFIP2 MSTN MSTN TGFBR3 TGFBR3 INHBB INHBB PARD6B PARD6B SCNN1A SCNN1A LOC101327238 LOC101327238 PARD3B PARD3B ANKRD1 ANKRD1 GDF9 GDF9 TWSG1 TWSG1 BMPR1B BMPR1B TOX4 TOX4 TGFB3 TGFB3 ARRDC5 ARRDC5 ACVR1C ACVR1C BMP7 BMP7 MPP5 MPP5 LLGL2 LLGL2 WBP2 WBP2 RAPGEF2 RAPGEF2 BMP6 BMP6 ARMC9 ARMC9 ZFYVE9 ZFYVE9 WWC1 WWC1 SMAD5 SMAD5 ACVR2A ACVR2A AMOTL1 AMOTL1 VGLL4 VGLL4 ENSTTRP00000016084 ENSTTRP00000016084 TTLL10 TTLL10 GDF5 GDF5 ENSTTRP00000016140 ENSTTRP00000016140 CUNH20orf173 CUNH20orf173 HECW2 HECW2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACTL7BActin-like protein 7B. (417 aa)
EPB41L4BBand 4.1-like protein 4B isoform X3. (856 aa)
NF2Merlin isoform X2. (567 aa)
ARRDC3Arrestin domain-containing protein 3 isoform X1. (414 aa)
SGK1Non-specific serine/threonine protein kinase. (405 aa)
CYR61Protein CYR61. (382 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
SKILSki-like protein isoform X1. (681 aa)
AMOTL2Angiomotin-like protein 2 isoform X2. (777 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1301 aa)
WWP1E3 ubiquitin-protein ligase. (921 aa)
SPINK14LOW QUALITY PROTEIN: serine protease inhibitor Kazal-type 14-like. (82 aa)
PARD6GPartitioning defective 6 homolog gamma. (367 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ACVR1BActivin A receptor type 1B. (504 aa)
CCN2Connective tissue growth factor. (349 aa)
MPDZMultiple PDZ domain protein. (2023 aa)
SMURF1E3 ubiquitin-protein ligase. (738 aa)
SMAD3Mothers against decapentaplegic homolog 3. (291 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (234 aa)
AMOTAngiomotin. (998 aa)
NODALNodal homolog. (348 aa)
NEDD4LE3 ubiquitin-protein ligase NEDD4-like isoform X3. (992 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
PTPN14Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1157 aa)
INHBAInhibin beta A chain. (421 aa)
LOC101324780Rho guanine nucleotide exchange factor 18-like. (1159 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
EPDR1LOW QUALITY PROTEIN: mammalian ependymin-related protein 1. (325 aa)
MAGI1Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 isoform X4. (1452 aa)
BORAProtein aurora borealis isoform X1. (617 aa)
PIBF1Progesterone-induced-blocking factor 1 isoform X4. (756 aa)
KLF5Krueppel-like factor 5. (370 aa)
SMAD7Mothers against decapentaplegic homolog 7 isoform X1. (426 aa)
ANKFN1Ankyrin repeat and fibronectin type-III domain-containing protein 1. (763 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (579 aa)
NBL1Neuroblastoma suppressor of tumorigenicity 1 isoform X2. (211 aa)
ACVRL1Activin A receptor like type 1. (497 aa)
BNC1Zinc finger protein basonuclin-1 isoform X2. (988 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (683 aa)
TEAD2Transcriptional enhancer factor TEF-4 isoform X2. (447 aa)
ACVR2BActivin A receptor type 2B. (511 aa)
WWP2E3 ubiquitin-protein ligase. (868 aa)
KCNJ1ATP-sensitive inward rectifier potassium channel 1 isoform X1. (389 aa)
BMP5Bone morphogenetic protein 5 isoform X2. (454 aa)
CHRDL2Chordin like 2. (452 aa)
LATS1Serine/threonine-protein kinase LATS1. (958 aa)
ARRDC1Arrestin domain containing 1. (425 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (651 aa)
STK3Serine/threonine-protein kinase 3 isoform X1. (480 aa)
RAP2CRas-related protein Rap-2c. (183 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1 isoform X1. (1599 aa)
TEAD1Transcriptional enhancer factor TEF-1 isoform X4. (426 aa)
MOB1AMOB kinase activator 1A. (215 aa)
WWC2Protein WWC2 isoform X1. (1145 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
NUMBLNumb-like protein isoform X1. (581 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (435 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (485 aa)
TEAD4TEA domain transcription factor 4. (431 aa)
CRB3Crumbs cell polarity complex component 3. (123 aa)
SMAD9Mothers against decapentaplegic homolog. (466 aa)
TTLL9Tubulin tyrosine ligase like 9. (439 aa)
NEDD4E3 ubiquitin-protein ligase. (1193 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
LLGL1Lethal(2) giant larvae protein homolog 1-like. (1065 aa)
MOB1BMOB kinase activator 1B. (265 aa)
ENSTTRP00000008060annotation not available (447 aa)
RC3H1Roquin-1 isoform X1. (1135 aa)
PATJinaD-like protein isoform X4. (1797 aa)
CRB1Protein crumbs homolog 1. (1405 aa)
RNF212BRING finger protein 212B. (300 aa)
ZFYVE16Zinc finger FYVE domain-containing protein 16 isoform X2. (1545 aa)
SMURF2E3 ubiquitin-protein ligase. (648 aa)
PARD3Partitioning defective 3 homolog isoform X1. (1281 aa)
MAGI3LOW QUALITY PROTEIN: membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3. (1367 aa)
HECW1E3 ubiquitin-protein ligase HECW1. (1580 aa)
PARD6APar-6 family cell polarity regulator alpha. (339 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
NUMBProtein numb homolog isoform X1. (650 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
TEAD3Transcriptional enhancer factor TEF-5 isoform X1. (472 aa)
SAV1Protein salvador homolog 1. (385 aa)
AMHR2anti-Mullerian hormone receptor type 2. (576 aa)
GDF11Growth differentiation factor 11. (313 aa)
SOSTDC1Sclerostin domain-containing protein 1. (229 aa)
SKISki oncogene. (633 aa)
LATS2Large tumor suppressor kinase 2. (992 aa)
DRC7Dynein regulatory complex subunit 7. (784 aa)
ERFEErythroferrone. (134 aa)
ENSTTRP00000009655annotation not available (318 aa)
SMAD6SMAD family member 6. (492 aa)
ZSWIM4Zinc finger SWIM domain-containing protein 4. (986 aa)
ENSTTRP00000010335annotation not available (350 aa)
CHRDChordin. (908 aa)
FSTL3Follistatin like 3. (262 aa)
LOC101325454Bone morphogenetic protein 8B. (241 aa)
CRB2Crumbs cell polarity complex component 2. (1254 aa)
GAPTProtein GAPT. (157 aa)
YAP1Transcriptional coactivator YAP1 isoform X4. (488 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (364 aa)
SMAD4Mothers against decapentaplegic homolog. (407 aa)
MAGI2Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2. (1434 aa)
PRKCZProtein kinase C zeta. (592 aa)
ZSWIM8Zinc finger SWIM domain-containing protein 8. (1222 aa)
NDFIP1NEDD4 family-interacting protein 1 isoform X2. (221 aa)
FSTFollistatin isoform X2. (343 aa)
GDF6Growth/differentiation factor 6. (458 aa)
ENSTTRP00000011729annotation not available (367 aa)
ITCHE3 ubiquitin-protein ligase. (861 aa)
FRMD6FERM domain-containing protein 6 isoform X1. (589 aa)
SALL2Sal-like protein 2 isoform X2. (1002 aa)
TGFB1Transforming growth factor beta 1. (338 aa)
INHBCInhibin beta C chain. (247 aa)
INHBEInhibin subunit beta E. (351 aa)
GDF2Growth/differentiation factor 2. (431 aa)
RAPGEF6Rap guanine nucleotide exchange factor 6 isoform X1. (1602 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (458 aa)
NDFIP2NEDD4 family-interacting protein 2. (336 aa)
MSTNGrowth/differentiation factor 8. (375 aa)
TGFBR3Transforming growth factor beta receptor type 3 isoform X4. (848 aa)
INHBBInhibin beta B chain. (407 aa)
PARD6BPartitioning defective 6 homolog beta. (372 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (539 aa)
LOC101327238Left-right determination factor. (201 aa)
PARD3BPartitioning defective 3 homolog B. (1202 aa)
ANKRD1Ankyrin repeat domain-containing protein 1. (318 aa)
GDF9Growth/differentiation factor 9 isoform X1. (454 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
TOX4TOX high mobility group box family member 4 isoform X1. (619 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
ARRDC5LOW QUALITY PROTEIN: arrestin domain-containing protein 5. (328 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (492 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
MPP5MAGUK p55 subfamily member 5 isoform X1; Belongs to the MAGUK family. (621 aa)
LLGL2Lethal(2) giant larvae protein homolog 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1068 aa)
WBP2WW domain binding protein 2. (241 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2 isoform X6. (1495 aa)
BMP6Bone morphogenetic protein 6. (304 aa)
ARMC9lisH domain-containing protein ARMC9 isoform X1. (664 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1422 aa)
WWC1Protein KIBRA. (1118 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
AMOTL1Angiomotin-like protein 1 isoform X1. (958 aa)
VGLL4Transcription cofactor vestigial-like protein 4 isoform X5. (164 aa)
ENSTTRP00000016084annotation not available (168 aa)
TTLL10Inactive polyglycylase TTLL10. (654 aa)
GDF5Growth/differentiation factor 5. (489 aa)
ENSTTRP00000016140annotation not available (669 aa)
CUNH20orf173LOW QUALITY PROTEIN: uncharacterized protein C20orf173 homolog; Belongs to the glycosyltransferase 29 family. (152 aa)
HECW2E3 ubiquitin-protein ligase HECW2 isoform X5. (1571 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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