STRINGSTRING
SKIL SKIL LTBP3 LTBP3 SPINK14 SPINK14 BMP2 BMP2 SMAD2 SMAD2 ACVR1B ACVR1B SMURF1 SMURF1 SMAD3 SMAD3 BAMBI BAMBI NODAL NODAL INHBA INHBA BMP3 BMP3 SMAD7 SMAD7 TGFBR2 TGFBR2 ACVRL1 ACVRL1 BMPR2 BMPR2 ACVR2B ACVR2B BMP5 BMP5 LTBP1 LTBP1 FGF14 FGF14 ACVR1 ACVR1 SMAD9 SMAD9 SMAD1 SMAD1 BMPR1A BMPR1A ZFYVE16 ZFYVE16 SMURF2 SMURF2 BMP4 BMP4 BMP15 BMP15 AMHR2 AMHR2 GDF11 GDF11 SKI SKI ENSTTRP00000009655 ENSTTRP00000009655 SMAD6 SMAD6 CHRD CHRD FSTL3 FSTL3 GAPT GAPT INHA INHA SMAD4 SMAD4 FST FST GDF6 GDF6 ENSTTRP00000011729 ENSTTRP00000011729 TGFB1 TGFB1 INHBC INHBC INHBE INHBE GDF2 GDF2 BMP10 BMP10 TGFB2 TGFB2 TGFBR1 TGFBR1 MSTN MSTN TGFBR3 TGFBR3 INHBB INHBB LOC101327238 LOC101327238 GDF9 GDF9 BMPR1B BMPR1B TGFB3 TGFB3 ACVR1C ACVR1C BMP7 BMP7 BMP6 BMP6 ZFYVE9 ZFYVE9 SMAD5 SMAD5 ACVR2A ACVR2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SKILSki-like protein isoform X1. (681 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1301 aa)
SPINK14LOW QUALITY PROTEIN: serine protease inhibitor Kazal-type 14-like. (82 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ACVR1BActivin A receptor type 1B. (504 aa)
SMURF1E3 ubiquitin-protein ligase. (738 aa)
SMAD3Mothers against decapentaplegic homolog 3. (291 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (234 aa)
NODALNodal homolog. (348 aa)
INHBAInhibin beta A chain. (421 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
SMAD7Mothers against decapentaplegic homolog 7 isoform X1. (426 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (579 aa)
ACVRL1Activin A receptor like type 1. (497 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ACVR2BActivin A receptor type 2B. (511 aa)
BMP5Bone morphogenetic protein 5 isoform X2. (454 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1 isoform X1. (1599 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (485 aa)
SMAD9Mothers against decapentaplegic homolog. (466 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
ZFYVE16Zinc finger FYVE domain-containing protein 16 isoform X2. (1545 aa)
SMURF2E3 ubiquitin-protein ligase. (648 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
AMHR2anti-Mullerian hormone receptor type 2. (576 aa)
GDF11Growth differentiation factor 11. (313 aa)
SKISki oncogene. (633 aa)
ENSTTRP00000009655annotation not available (318 aa)
SMAD6SMAD family member 6. (492 aa)
CHRDChordin. (908 aa)
FSTL3Follistatin like 3. (262 aa)
GAPTProtein GAPT. (157 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (364 aa)
SMAD4Mothers against decapentaplegic homolog. (407 aa)
FSTFollistatin isoform X2. (343 aa)
GDF6Growth/differentiation factor 6. (458 aa)
ENSTTRP00000011729annotation not available (367 aa)
TGFB1Transforming growth factor beta 1. (338 aa)
INHBCInhibin beta C chain. (247 aa)
INHBEInhibin subunit beta E. (351 aa)
GDF2Growth/differentiation factor 2. (431 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (458 aa)
MSTNGrowth/differentiation factor 8. (375 aa)
TGFBR3Transforming growth factor beta receptor type 3 isoform X4. (848 aa)
INHBBInhibin beta B chain. (407 aa)
LOC101327238Left-right determination factor. (201 aa)
GDF9Growth/differentiation factor 9 isoform X1. (454 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (492 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
BMP6Bone morphogenetic protein 6. (304 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1422 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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