STRINGSTRING
MCM6 MCM6 MCM3 MCM3 CDT1 CDT1 CDC7 CDC7 DBF4 DBF4 MCM5 MCM5 MCM4 MCM4 ORC3 ORC3 ORC5 ORC5 MCM10 MCM10 ORC2 ORC2 MCM7 MCM7 MCM8 MCM8 ORC6 ORC6 MCM9 MCM9 CDC45 CDC45 GMNN GMNN ORC1 ORC1 ORC4 ORC4 CDC6 CDC6 MCM2 MCM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM6DNA helicase; Belongs to the MCM family. (820 aa)
MCM3DNA helicase; Belongs to the MCM family. (801 aa)
CDT1DNA replication factor Cdt1. (372 aa)
CDC7Cell division cycle 7-related protein kinase. (572 aa)
DBF4Protein DBF4 homolog A isoform X1. (675 aa)
MCM5DNA replication licensing factor MCM5-like. (734 aa)
MCM4DNA helicase; Belongs to the MCM family. (692 aa)
ORC3Origin recognition complex subunit 3 isoform X3. (714 aa)
ORC5Origin recognition complex subunit 5 isoform X1. (376 aa)
MCM10Protein MCM10 homolog. (872 aa)
ORC2Origin recognition complex subunit 2 isoform X1. (496 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (718 aa)
MCM8DNA helicase MCM8 isoform X1; Belongs to the MCM family. (821 aa)
ORC6Origin recognition complex subunit 6. (252 aa)
MCM9DNA helicase MCM9 isoform X4; Belongs to the MCM family. (696 aa)
CDC45Cell division control protein 45 homolog. (567 aa)
GMNNGeminin. (210 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (499 aa)
MCM2Minichromosome maintenance complex component 2. (905 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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