(39 nodes) Mixed, incl. Ligand-gated ion channel signaling pathway, and Guanylate kinase homologues. network (Tursiops truncatus)

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GRIN3A	Glutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1111 aa)
	GRIK1	Glutamate receptor ionotropic, kainate 1; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (953 aa)
	CAMK2D	Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4; Belongs to the protein kinase superfamily. (498 aa)
	GRIN3B	LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 3B-like; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1027 aa)
	GRIN1	Glutamate receptor ionotropic, NMDA 1-like. (954 aa)
	GRIK3	Glutamate ionotropic receptor kainate type subunit 3. (880 aa)
	GRIN2C	Glutamate receptor ionotropic, NMDA 2C. (1222 aa)
	APBA1	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1. (828 aa)
	STXBP2	Syntaxin binding protein 2. (593 aa)
	APBA3	Amyloid beta A4 precursor protein-binding family A member 3. (384 aa)
	MPP2	MAGUK p55 subfamily member 2 isoform X1; Belongs to the MAGUK family. (573 aa)
	NCALD	Neurocalcin delta. (172 aa)
	GRIK2	Glutamate receptor ionotropic, kainate 2. (869 aa)
	TJAP1	Tight junction associated protein 1. (544 aa)
	CASK	Peripheral plasma membrane protein CASK isoform X8; Belongs to the MAGUK family. (926 aa)
	DLG5	Disks large homolog 5; Belongs to the MAGUK family. (1816 aa)
	GRIN2D	Glutamate receptor ionotropic, NMDA 2D. (1332 aa)
	DLG3	Discs large MAGUK scaffold protein 3. (843 aa)
	CAMK2B	Calcium/calmodulin dependent protein kinase II beta. (489 aa)
	MPP1	55 kDa erythrocyte membrane protein; Belongs to the MAGUK family. (466 aa)
	CASKIN1	CASK interacting protein 1. (1435 aa)
	GRIK5	Glutamate ionotropic receptor kainate type subunit 5. (968 aa)
	DLG4	Discs large MAGUK scaffold protein 4. (767 aa)
	APBA2	Amyloid beta A4 precursor protein-binding family A member 2-like. (749 aa)
	CAMK2G	Calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X5. (535 aa)
	GRIK4	Glutamate receptor ionotropic, kainate 4; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (957 aa)
	DLG1	Disks large homolog 1 isoform X3; Belongs to the MAGUK family. (920 aa)
	RTKN	LOW QUALITY PROTEIN: rhotekin. (527 aa)
	LIN7C	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (196 aa)
	HPCA	Neuron-specific calcium-binding protein hippocalcin. (193 aa)
	ENSTTRP00000013721	annotation not available (118 aa)
	CAMK2A	Calcium/calmodulin-dependent protein kinase type II subunit alpha. (539 aa)
	LIN7A	Protein lin-7 homolog A isoform X1. (233 aa)
	DLG2	Disks large homolog 2 isoform X2. (966 aa)
	GRIN2A	Glutamate receptor ionotropic, NMDA 2A isoform X1. (1464 aa)
	MPP6	MAGUK p55 subfamily member 6; Belongs to the MAGUK family. (540 aa)
	SCRIB	Protein scribble homolog. (1596 aa)
	LIN7B	Lin-7 homolog B, crumbs cell polarity complex component. (207 aa)
	GRIN2B	Glutamate receptor ionotropic, NMDA 2B. (1479 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBA1	CAMK2A	ENSTTRP00000002970	ENSTTRP00000013896	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Calcium/calmodulin-dependent protein kinase type II subunit alpha.	0.754
APBA1	CAMK2B	ENSTTRP00000002970	ENSTTRP00000007497	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Calcium/calmodulin dependent protein kinase II beta.	0.754
APBA1	CAMK2D	ENSTTRP00000002970	ENSTTRP00000000907	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4; Belongs to the protein kinase superfamily.	0.754
APBA1	CASK	ENSTTRP00000002970	ENSTTRP00000006840	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Peripheral plasma membrane protein CASK isoform X8; Belongs to the MAGUK family.	0.997
APBA1	DLG1	ENSTTRP00000002970	ENSTTRP00000011781	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Disks large homolog 1 isoform X3; Belongs to the MAGUK family.	0.471
APBA1	DLG2	ENSTTRP00000002970	ENSTTRP00000013949	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Disks large homolog 2 isoform X2.	0.493
APBA1	DLG3	ENSTTRP00000002970	ENSTTRP00000007459	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Discs large MAGUK scaffold protein 3.	0.460
APBA1	DLG4	ENSTTRP00000002970	ENSTTRP00000009211	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Discs large MAGUK scaffold protein 4.	0.463
APBA1	DLG5	ENSTTRP00000002970	ENSTTRP00000007372	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Disks large homolog 5; Belongs to the MAGUK family.	0.469
APBA1	LIN7A	ENSTTRP00000002970	ENSTTRP00000013931	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Protein lin-7 homolog A isoform X1.	0.821
APBA1	LIN7B	ENSTTRP00000002970	ENSTTRP00000016208	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Lin-7 homolog B, crumbs cell polarity complex component.	0.739
APBA1	LIN7C	ENSTTRP00000002970	ENSTTRP00000012834	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.739
APBA1	MPP1	ENSTTRP00000002970	ENSTTRP00000007687	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	55 kDa erythrocyte membrane protein; Belongs to the MAGUK family.	0.832
APBA1	MPP2	ENSTTRP00000002970	ENSTTRP00000004911	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	MAGUK p55 subfamily member 2 isoform X1; Belongs to the MAGUK family.	0.767
APBA1	MPP6	ENSTTRP00000002970	ENSTTRP00000015838	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	MAGUK p55 subfamily member 6; Belongs to the MAGUK family.	0.767
APBA1	STXBP2	ENSTTRP00000002970	ENSTTRP00000003680	Amyloid beta A4 precursor protein-binding family A member 1 isoform X1.	Syntaxin binding protein 2.	0.906
APBA2	CAMK2A	ENSTTRP00000009417	ENSTTRP00000013896	Amyloid beta A4 precursor protein-binding family A member 2-like.	Calcium/calmodulin-dependent protein kinase type II subunit alpha.	0.754
APBA2	CAMK2B	ENSTTRP00000009417	ENSTTRP00000007497	Amyloid beta A4 precursor protein-binding family A member 2-like.	Calcium/calmodulin dependent protein kinase II beta.	0.754
APBA2	CAMK2D	ENSTTRP00000009417	ENSTTRP00000000907	Amyloid beta A4 precursor protein-binding family A member 2-like.	Calcium/calmodulin-dependent protein kinase type II subunit delta isoform X4; Belongs to the protein kinase superfamily.	0.754
APBA2	CASK	ENSTTRP00000009417	ENSTTRP00000006840	Amyloid beta A4 precursor protein-binding family A member 2-like.	Peripheral plasma membrane protein CASK isoform X8; Belongs to the MAGUK family.	0.992