56 items (Tursiops truncatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PLCB2	Phosphoinositide phospholipase C. (1184 aa)
	DRD3	D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	CASR	Extracellular calcium-sensing receptor isoform X1. (1091 aa)
	GRM2	Metabotropic glutamate receptor 2. (1080 aa)
	HTR1A	5-hydroxytryptamine receptor 1A. (422 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	GNB4	Guanine nucleotide-binding protein subunit beta-4. (340 aa)
	KCNJ9	Potassium inwardly rectifying channel subfamily J member 9. (283 aa)
	GRK2	G protein-coupled receptor kinase 2. (651 aa)
	HTR1F	5-hydroxytryptamine receptor 1F. (365 aa)
	KCNJ16	Inward rectifier potassium channel 16 isoform X1. (370 aa)
	GNG8	G protein subunit gamma 8. (70 aa)
	KCNJ3	G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
	PREX1	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein. (1653 aa)
	HTR1E	5-hydroxytryptamine receptor 1E. (365 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	GNB3	G protein subunit beta 3. (340 aa)
	ADRA1A	alpha-1A adrenergic receptor. (423 aa)
	KCNJ6	G protein-activated inward rectifier potassium channel 2. (414 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	GNB2	G protein subunit beta 2. (340 aa)
	GNAI1	Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	DRD2	D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (445 aa)
	GPSM1	G-protein-signaling modulator 1. (650 aa)
	GNAI2	G protein subunit alpha i2. (351 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	PTGER1	Prostaglandin E receptor 1. (408 aa)
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1. (928 aa)
	CHRM2	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
	GNAQ	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
	LPAR1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	KCNJ5	G protein-activated inward rectifier potassium channel 4 isoform X1. (419 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
	ADRA1D	alpha-1D adrenergic receptor. (569 aa)
	HTR5A	5-hydroxytryptamine receptor 5A. (357 aa)
	GNG13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
	PTGER2	Prostaglandin E2 receptor EP2 subtype; Belongs to the G-protein coupled receptor 1 family. (357 aa)
	GABBR2	Gamma-aminobutyric acid type B receptor subunit 2. (940 aa)
	PTGER4	Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (484 aa)
	GNA14	Guanine nucleotide-binding protein subunit alpha-14. (328 aa)
	GNA11	G protein subunit alpha 11. (359 aa)
	GNA15	G protein subunit alpha 15. (325 aa)
	ADRA1B	alpha-1B adrenergic receptor. (395 aa)
	GRM3	Metabotropic glutamate receptor 3 isoform X1. (876 aa)
	GNAO1	G protein subunit alpha o1. (354 aa)
	PTGER3	Prostaglandin E2 receptor EP3 subtype isoform X2. (448 aa)
	HTR7	5-hydroxytryptamine receptor 7 isoform X2; Belongs to the G-protein coupled receptor 1 family. (306 aa)
	GNG12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (53 aa)
	APLNR	Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
	KCNJ15	ATP-sensitive inward rectifier potassium channel 15. (375 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	ENSTTRP00000015348	annotation not available (321 aa)
	PDCL	Phosducin-like protein. (300 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRA1A	ADRA1B	ENSTTRP00000004551	ENSTTRP00000012344	alpha-1A adrenergic receptor.	alpha-1B adrenergic receptor.	0.918
ADRA1A	ADRA1D	ENSTTRP00000004551	ENSTTRP00000009418	alpha-1A adrenergic receptor.	alpha-1D adrenergic receptor.	0.914
ADRA1A	ENSTTRP00000015348	ENSTTRP00000004551	ENSTTRP00000015348	alpha-1A adrenergic receptor.	annotation not available	0.605
ADRA1A	GNA11	ENSTTRP00000004551	ENSTTRP00000011654	alpha-1A adrenergic receptor.	G protein subunit alpha 11.	0.923
ADRA1A	GNA14	ENSTTRP00000004551	ENSTTRP00000011001	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit alpha-14.	0.891
ADRA1A	GNA15	ENSTTRP00000004551	ENSTTRP00000011655	alpha-1A adrenergic receptor.	G protein subunit alpha 15.	0.880
ADRA1A	GNAQ	ENSTTRP00000004551	ENSTTRP00000008242	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1.	0.923
ADRA1A	GNB2	ENSTTRP00000004551	ENSTTRP00000005832	alpha-1A adrenergic receptor.	G protein subunit beta 2.	0.666
ADRA1A	GNB3	ENSTTRP00000004551	ENSTTRP00000004434	alpha-1A adrenergic receptor.	G protein subunit beta 3.	0.666
ADRA1A	GNB4	ENSTTRP00000004551	ENSTTRP00000001481	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit beta-4.	0.666
ADRA1A	GNG11	ENSTTRP00000004551	ENSTTRP00000015265	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.533
ADRA1A	GNG12	ENSTTRP00000004551	ENSTTRP00000014277	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.570
ADRA1A	GNG13	ENSTTRP00000004551	ENSTTRP00000009670	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.622
ADRA1A	GNG2	ENSTTRP00000004551	ENSTTRP00000005402	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.666
ADRA1A	GNG4	ENSTTRP00000004551	ENSTTRP00000007365	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.674
ADRA1A	GNG5	ENSTTRP00000004551	ENSTTRP00000000740	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.623
ADRA1A	GNG7	ENSTTRP00000004551	ENSTTRP00000006650	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.570
ADRA1A	GNG8	ENSTTRP00000004551	ENSTTRP00000003018	alpha-1A adrenergic receptor.	G protein subunit gamma 8.	0.611
ADRA1A	GNGT1	ENSTTRP00000004551	ENSTTRP00000015263	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.587
ADRA1A	GNGT2	ENSTTRP00000004551	ENSTTRP00000004330	alpha-1A adrenergic receptor.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.624