(12 nodes) Mixed, incl. Histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore, and Histone H3-K27 demethylation network (Tursiops truncatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101322931	Histone H3; Belongs to the histone H3 family. (136 aa)
	ENSTTRP00000004825	annotation not available (136 aa)
	H2BU1	Histone H2B; Belongs to the histone H2B family. (126 aa)
	KDM6A	Lysine-specific demethylase 6A isoform X4. (1346 aa)
	KDM6B	Dynein heavy chain 2, axonemal. (1642 aa)
	ENSTTRP00000011747	annotation not available (136 aa)
	LOC101322612-2	Histone H3.1. (136 aa)
	SETD2	Histone-lysine N-methyltransferase SETD2. (2054 aa)
	LOC101329540	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC101322612-4	Histone H3.1. (136 aa)
	LOC101320102-6	Histone H4. (103 aa)
	LOC101320102-9	Histone H4. (103 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTTRP00000004825	ENSTTRP00000011747	ENSTTRP00000004825	ENSTTRP00000011747	annotation not available	annotation not available	0.711
ENSTTRP00000004825	H2BU1	ENSTTRP00000004825	ENSTTRP00000006014	annotation not available	Histone H2B; Belongs to the histone H2B family.	0.869
ENSTTRP00000004825	KDM6A	ENSTTRP00000004825	ENSTTRP00000006394	annotation not available	Lysine-specific demethylase 6A isoform X4.	0.904
ENSTTRP00000004825	KDM6B	ENSTTRP00000004825	ENSTTRP00000009761	annotation not available	Dynein heavy chain 2, axonemal.	0.916
ENSTTRP00000004825	LOC101320102-6	ENSTTRP00000004825	ENSTTRP00000015874	annotation not available	Histone H4.	0.853
ENSTTRP00000004825	LOC101320102-9	ENSTTRP00000004825	ENSTTRP00000015900	annotation not available	Histone H4.	0.853
ENSTTRP00000004825	LOC101322612-2	ENSTTRP00000004825	ENSTTRP00000012770	annotation not available	Histone H3.1.	0.619
ENSTTRP00000004825	LOC101322612-4	ENSTTRP00000004825	ENSTTRP00000015862	annotation not available	Histone H3.1.	0.619
ENSTTRP00000004825	LOC101329540	ENSTTRP00000004825	ENSTTRP00000015055	annotation not available	Histone H3; Belongs to the histone H3 family.	0.710
ENSTTRP00000004825	SETD2	ENSTTRP00000004825	ENSTTRP00000015037	annotation not available	Histone-lysine N-methyltransferase SETD2.	0.884
ENSTTRP00000011747	ENSTTRP00000004825	ENSTTRP00000011747	ENSTTRP00000004825	annotation not available	annotation not available	0.711
ENSTTRP00000011747	H2BU1	ENSTTRP00000011747	ENSTTRP00000006014	annotation not available	Histone H2B; Belongs to the histone H2B family.	0.950
ENSTTRP00000011747	KDM6A	ENSTTRP00000011747	ENSTTRP00000006394	annotation not available	Lysine-specific demethylase 6A isoform X4.	0.955
ENSTTRP00000011747	KDM6B	ENSTTRP00000011747	ENSTTRP00000009761	annotation not available	Dynein heavy chain 2, axonemal.	0.895
ENSTTRP00000011747	LOC101320102-6	ENSTTRP00000011747	ENSTTRP00000015874	annotation not available	Histone H4.	0.853
ENSTTRP00000011747	LOC101320102-9	ENSTTRP00000011747	ENSTTRP00000015900	annotation not available	Histone H4.	0.853
ENSTTRP00000011747	LOC101322612-2	ENSTTRP00000011747	ENSTTRP00000012770	annotation not available	Histone H3.1.	0.711
ENSTTRP00000011747	LOC101322612-4	ENSTTRP00000011747	ENSTTRP00000015862	annotation not available	Histone H3.1.	0.711
ENSTTRP00000011747	LOC101322931	ENSTTRP00000011747	ENSTTRP00000004785	annotation not available	Histone H3; Belongs to the histone H3 family.	0.711
ENSTTRP00000011747	SETD2	ENSTTRP00000011747	ENSTTRP00000015037	annotation not available	Histone-lysine N-methyltransferase SETD2.	0.711