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PNPT1 PNPT1 LOC101326630 LOC101326630 PAN3 PAN3 FAM170B FAM170B TREX2 TREX2 TUT7 TUT7 EQTN EQTN LIN28A LIN28A PAN2 PAN2 TRNT1 TRNT1 MTCL1 MTCL1 DIS3L2 DIS3L2 LOC101335974 LOC101335974 PABPC4 PABPC4 REXO2 REXO2 REXO1 REXO1 TUT4 TUT4 REXO5 REXO5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1. (729 aa)
LOC101326630Speckle targeted PIP5K1A-regulated poly(A) polymerase isoform X3. (871 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (739 aa)
FAM170BLOW QUALITY PROTEIN: protein FAM170B. (291 aa)
TREX2Three prime repair exonuclease 2. (248 aa)
TUT7Terminal uridylyltransferase 7 isoform X5. (1481 aa)
EQTNUncharacterized protein LOC101320778. (294 aa)
LIN28AProtein lin-28 homolog A. (194 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1199 aa)
TRNT1CCA tRNA nucleotidyltransferase 1, mitochondrial; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (434 aa)
MTCL1Microtubule cross-linking factor 1 isoform X2. (1643 aa)
DIS3L2DIS3-like exonuclease 2 isoform X2. (801 aa)
LOC101335974Polyadenylate-binding protein 1-like 2. (200 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (555 aa)
REXO2Oligoribonuclease, mitochondrial. (237 aa)
REXO1RNA exonuclease 1 homolog. (1206 aa)
TUT4Terminal uridylyltransferase 4 isoform X5. (1647 aa)
REXO5Putative RNA exonuclease NEF-sp isoform X1. (774 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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