STRINGSTRING
GRWD1 GRWD1 ORC3 ORC3 ORC5 ORC5 MCM10 MCM10 ORC2 ORC2 CDC45 CDC45 ORC1 ORC1 ORC4 ORC4 CDC6 CDC6 MCM2 MCM2 DHX9 DHX9 MCM5 MCM5 POLA1 POLA1 KAT7 KAT7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRWD1Glutamate-rich WD repeat-containing protein 1. (446 aa)
ORC3Origin recognition complex subunit 3 isoform X3. (714 aa)
ORC5Origin recognition complex subunit 5 isoform X1. (376 aa)
MCM10Protein MCM10 homolog. (872 aa)
ORC2Origin recognition complex subunit 2 isoform X1. (496 aa)
CDC45Cell division control protein 45 homolog. (567 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (499 aa)
MCM2Minichromosome maintenance complex component 2. (905 aa)
DHX9ATP-dependent RNA helicase A isoform X1. (1153 aa)
MCM5DNA replication licensing factor MCM5-like. (734 aa)
POLA1DNA polymerase. (1467 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.