STRINGSTRING
E2F7 E2F7 MCRS1 MCRS1 E2F8 E2F8 ZMPSTE24 ZMPSTE24 CDC7 CDC7 STOML2 STOML2 PCNA PCNA CDK2 CDK2 DBF4 DBF4 ENSTTRP00000006211 ENSTTRP00000006211 BCAR3 BCAR3 TIMELESS TIMELESS EHMT2 EHMT2 DNA2 DNA2 GLI1 GLI1 INO80D INO80D INO80B INO80B DHX9 DHX9 ACTR5 ACTR5 WAPL WAPL WBP1 WBP1 ACTR8 ACTR8 EGFR EGFR RFC4 RFC4 ANKRD17 ANKRD17 CIZ1 CIZ1 BLM BLM GMNN GMNN BRPF3 BRPF3 UCN UCN PDS5A PDS5A ENDOG ENDOG INO80 INO80 RFC3 RFC3 CDAN1 CDAN1 USP37 USP37 ORC5 ORC5 BRCA2 BRCA2 DBF4B DBF4B NUCKS1 NUCKS1 CTC1 CTC1 CHTF18 CHTF18 TIPIN TIPIN ATR ATR SSBP1 SSBP1 JADE3 JADE3 UCHL5 UCHL5 NFRKB NFRKB SMARCAL1 SMARCAL1 ORC3 ORC3 ACTL6A ACTL6A POLG2 POLG2 RFC2 RFC2 MEAF6 MEAF6 GINS3 GINS3 METTL4 METTL4 JADE1 JADE1 NPM2 NPM2 GINS2 GINS2 DERPC DERPC SMC3 SMC3 INO80E INO80E NUGGC NUGGC TICRR TICRR ESCO1 ESCO1 DONSON DONSON EGF EGF LIG3 LIG3 ZNF830 ZNF830 ENPP7 ENPP7 CDT1 CDT1 ATRX ATRX ZRANB3 ZRANB3 WRNIP1 WRNIP1 TERF1 TERF1 GINS4 GINS4 ATAD5 ATAD5 OBI1 OBI1 TSPYL2 TSPYL2 ESCO2 ESCO2 STN1 STN1 SMARCA5 SMARCA5 LOC101338489 LOC101338489 RAD17 RAD17 CHRAC1 CHRAC1 RBBP6 RBBP6 GMNC GMNC EREG EREG DACH1 DACH1 CCNA2 CCNA2 RUVBL2 RUVBL2 POLE3 POLE3 RUVBL1 RUVBL1 BAZ1A BAZ1A AICDA AICDA KAT7 KAT7 DSCC1 DSCC1 FBXO5 FBXO5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
E2F7Transcription factor E2F7. (904 aa)
MCRS1LOW QUALITY PROTEIN: microspherule protein 1. (472 aa)
E2F8Transcription factor E2F8 isoform X1. (866 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
CDC7Cell division cycle 7-related protein kinase. (572 aa)
STOML2Stomatin like 2. (356 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (187 aa)
CDK2Cyclin dependent kinase 2. (298 aa)
DBF4Protein DBF4 homolog A isoform X1. (675 aa)
ENSTTRP00000006211annotation not available (252 aa)
BCAR3Breast cancer anti-estrogen resistance protein 3 isoform X1. (824 aa)
TIMELESSProtein timeless homolog isoform X2. (1200 aa)
EHMT2Histone-lysine N-methyltransferase EHMT2. (1017 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1. (1059 aa)
GLI1Zinc finger protein GLI1. (1106 aa)
INO80DINO80 complex subunit D isoform X1. (803 aa)
INO80BINO80 complex subunit B. (355 aa)
DHX9ATP-dependent RNA helicase A isoform X1. (1153 aa)
ACTR5Actin-related protein 5; Belongs to the actin family. (482 aa)
WAPLWings apart-like protein homolog isoform X1. (1270 aa)
WBP1WW domain-binding protein 1. (300 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (620 aa)
EGFRReceptor protein-tyrosine kinase. (1211 aa)
RFC4Replication factor C subunit 4. (364 aa)
ANKRD17Ankyrin repeat domain-containing protein 17 isoform X3. (2578 aa)
CIZ1CDKN1A interacting zinc finger protein 1. (851 aa)
BLMBloom syndrome protein isoform X1. (1409 aa)
GMNNGeminin. (210 aa)
BRPF3Bromodomain and PHD finger-containing protein 3 isoform X1. (960 aa)
UCNUrocortin. (126 aa)
PDS5ASister chromatid cohesion protein PDS5 homolog A isoform X1. (1338 aa)
ENDOGEndonuclease G. (291 aa)
INO80DNA helicase INO80 isoform X1. (1536 aa)
RFC3Replication factor C subunit 3 isoform X2. (355 aa)
CDAN1Codanin-1 isoform X1. (1231 aa)
USP37Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (978 aa)
ORC5Origin recognition complex subunit 5 isoform X1. (376 aa)
BRCA2Breast cancer type 2 susceptibility protein. (3307 aa)
DBF4BProtein DBF4 homolog B. (589 aa)
NUCKS1Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 isoform X1. (306 aa)
CTC1CST complex subunit CTC1. (1156 aa)
CHTF18Chromosome transmission fidelity protein 18 homolog. (1090 aa)
TIPINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (297 aa)
ATRSerine/threonine-protein kinase ATR isoform X2; Belongs to the PI3/PI4-kinase family. (2623 aa)
SSBP1Single-stranded DNA-binding protein, mitochondrial isoform X2. (148 aa)
JADE3Protein Jade-3 isoform X1. (823 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (331 aa)
NFRKBNuclear factor related to kappa-B-binding protein. (1320 aa)
SMARCAL1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (944 aa)
ORC3Origin recognition complex subunit 3 isoform X3. (714 aa)
ACTL6AActin-like protein 6A; Belongs to the actin family. (429 aa)
POLG2DNA polymerase subunit gamma-2, mitochondrial isoform X2. (482 aa)
RFC2Replication factor C subunit 2. (316 aa)
MEAF6Chromatin modification-related protein MEAF6. (201 aa)
GINS3DNA replication complex GINS protein PSF3. (216 aa)
METTL4Methyltransferase-like protein 4 isoform X1; Belongs to the MT-A70-like family. (468 aa)
JADE1Protein Jade-1 isoform X1. (841 aa)
NPM2Nucleoplasmin-2 isoform X4. (129 aa)
GINS2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
DERPCLOW QUALITY PROTEIN: chromosome transmission fidelity protein 8 homolog. (450 aa)
SMC3Structural maintenance of chromosomes protein. (1215 aa)
INO80EINO80 complex subunit E. (243 aa)
NUGGCNuclear GTPase SLIP-GC. (800 aa)
TICRRTreslin. (1890 aa)
ESCO1N-acetyltransferase ESCO1 isoform X1. (845 aa)
DONSONProtein downstream neighbor of Son isoform X1. (457 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
LIG3DNA ligase. (1000 aa)
ZNF830Zinc finger protein 830. (371 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase family member 7. (442 aa)
CDT1DNA replication factor Cdt1. (372 aa)
ATRXTranscriptional regulator ATRX isoform X3. (2518 aa)
ZRANB3DNA annealing helicase and endonuclease ZRANB3 isoform X1. (1078 aa)
WRNIP1ATPase WRNIP1 isoform X2. (391 aa)
TERF1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (406 aa)
GINS4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (222 aa)
ATAD5ATPase family AAA domain-containing protein 5 isoform X1. (1830 aa)
OBI1RING finger protein 219. (719 aa)
TSPYL2Testis-specific Y-encoded-like protein 2; Belongs to the nucleosome assembly protein (NAP) family. (708 aa)
ESCO2N-acetyltransferase ESCO2. (601 aa)
STN1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (368 aa)
SMARCA5SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5. (983 aa)
LOC101338489Ankyrin repeat and KH domain-containing protein 1 isoform X4. (2600 aa)
RAD17Cell cycle checkpoint protein RAD17. (683 aa)
CHRAC1Chromatin accessibility complex protein 1. (132 aa)
RBBP6E3 ubiquitin-protein ligase RBBP6 isoform X1. (1781 aa)
GMNCGeminin coiled-coil domain-containing protein 1. (335 aa)
EREGProepiregulin isoform X2. (169 aa)
DACH1Dachshund family transcription factor 1. (748 aa)
CCNA2cyclin-A2; Belongs to the cyclin family. (431 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (443 aa)
POLE3DNA polymerase epsilon subunit 3. (147 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (454 aa)
BAZ1ABromodomain adjacent to zinc finger domain protein 1A isoform X2. (1549 aa)
AICDASingle-stranded DNA cytosine deaminase. (182 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
DSCC1Sister chromatid cohesion protein DCC1 isoform X1. (392 aa)
FBXO5F-box only protein 5 isoform X1. (448 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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